Comparison of Retinal Nerve Fiber Layer Measurements between NTG and HTG using GDx-VCC

• 발행기관: 대한안과학회
• 저자명: JI Yong Jung Jae-hyung Kim Michael S. Kook
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.20 No.1, 26~32쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.03.30

영문 초록

Purpose: To compare quantitative polarimetric measurements in eyes with NTG and HTG using GDx-VCC. Both groups were matched by age and glaucoma stage based on the Humphrey visual field test. Methods: We retrospectively reviewed the records of 146 patients who underwent Humphrey field analysis(HFA) and GDx-VCC. We compared outcomes of retinal nerve fiber layer (RNFL) parameters among the three groups by ANOVA and between each pair of groups using the Tukey-Kramer Post-Hoc test. We also evaluated the sensitivity and specificity of GDx-VCC in detecting glaucoma in each group. Results: The mean age and HFA mean deviation (MD) were 55.6±9.5 years and -0.8±1.5 dB in 47 control patients, 59.4±9.0 years and -5.77±4.38 dB in 49 NTG patients, and 59.4±11.7 years and -8.09±6.77 dB in 51 HTG patients, respectively. All thickness parameters were lower in HTG patients compared to NTG patients, but there were no significant differences in ratio parameters between age-matched early HTG and NTG patients. The sensitivity of GDx-VCC was significantly higher in both early and total HTG patients compared to the respective groups of NTG patients. Conclusions: Compared to eyes with NTG, eyes with HTG showed reduced RNFL thickness and ratio parameters when patients were age and visual field matched. GDx-VCC appeared to be more sensitive in detecting RNFL damage in HTG patients. Korean Journal of Ophthalmology 20(1):26-32, 2006

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키워드

Normal-tension glaucoma (NTG) High-tension glaucoma (HTG) scanning laser polarimetry with variable corneal compensation (GDx-VCC)