50세 이상 한국 여성들에게서 혈청 암배아항원 농도와 대사증후군의 관련성

• 영문명: Association between Serum Carcinoembryonic Antigen Levels within Normal Range and Metabolic Syndrome in Korean Women Aged ≥50 Years Old
• 발행기관: 대한임상노인의학회
• 저자명: 박혜민(Hye Min Park) 권유진(Yu Jin Kwon) 박혜윤(Hea Yoon Park) 이용제(Yong Jae Lee)
• 간행물 정보: 『대한임상노인의학회지』대한임상노인의학회지 제19권 제1호, 49~54쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2018.06.30

영문 초록

Background: The objective of this study was to investigate the relationship between serum carcinoembryonic antigen (CEA) levels and metabolic syndrome in Korean women aged ≥50 years old. Methods: This cross-sectional study included a total of 3,479 individuals who underwent health check-ups between November 2006 and July 2010 at the Health Promotion Center of Gangnam Severance Hospital in Seoul. Serum CEA levels were categorized into quartiles: Q1 (≤1.0 g/L), Q2 (1.1~1.4 g/L), Q3 (1.5~2.1 g/L), and Q4 (≥2.2 g/L). The odds ratio (OR) and 95% confidence interval (CI) for metabolic syndrome were calculated using multiple logistic regression analysis after adjusting for confounding factors across CEA quartiles. Results: The mean CEA levels were increased in people with obesity, high blood pressure, and high plasma glucose. Compared with the lowest CEA quartile, the OR (95% CI) for metabolic syndrome in the highest CEA quartile was 1.34 (1.03 to 1.73) after adjusting for age, cigarette smoking, alcohol intake, regular exercise, and leukocyte count. Conclusion: CEA was significantly related with metabolic syndrome in middle aged and elderly Korean females, and elevated CEA levels may be a surrogate marker for metabolic syndrome.

목차

Abstract

서론

대상 및 방법

결과

고찰

CONFLICTS OF INTEREST

REFERENCES

키워드

Carcinoembryonic antigen Metabolic syndrome Inflammation Elderly