애착의 관점에서 본 중독

• 영문명: Addiction in the Aspect of Attachment
• 발행기관: 한국중독정신의학회
• 저자명: 이계성(Kye-Seong Lee) 김대진(Dai-Jin Kim) 신정호(Jong-Ho Shin) 신상은(Sang-Eun Shin) 이명지(Myung-Ji Lee)
• 간행물 정보: 『중독정신의학』Vol.11, No.1, 3~9쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2007.04.30

영문 초록

Studies of addiction or substance abuse gave us much information about the neurobiology of reward and reward circuit. This review showed the possibility that the mesocorticolimbic pathway was primarily evolved to mediated ethologically relevant cues, such as a social attachment appeared important in maternal behavior in rats and pair bonding in monogamous voles. Specifically in the mesocorticolimbic pathway, activation of D2 receptor seemed to mediate drug addiction and the hedonic properties of social bond formation. A circuit linking the anterior hypothalamus (medial preoptic area) to the ventral tegmental area and the nucleus accumbens shell might be especially im-portant in mediating motivation and the rewarding properties of social interaction. The neuropeptides oxytocin and vasopressin released by social attachment & pair bonding appear to be critical linking social signals to the mesocorticolimbic circuit. In the aspect of attachment, returning the role of reward circuit that have been hijacked by addiction to where it bleongs is important part of being treat patients with drug addition. It could be the one way to help patient to feel happiness and security through reconnecting human relationships, by developing new trustworthy bonding to rely on and by restoring relationship among family to intimacy and closeness.

목차

서 론

뇌 보상 회로와 도파민

어미와 새끼 사이의 애착

짝형성과 애착-들쥐(Prairie vole；Microtus Ochrogaster) 중심으로

신경단백질(Neuropeptide)과 보상회로

결론과 의미

키워드

Addiction Reward Dopamine Attachment Oxytocin Vasopressin 중독 보상회로 도파민 애착 신경단백질.