본드흡입 환자에서의 사건관련전위 P300의 특성

• 영문명: Characteristics of Event-related Potentials in Glue-Sniffing Patients
• 발행기관: 한국중독정신의학회
• 저자명: 김종균(Chong-Kyun Kim) 최상섭(Sang-Sub Choi):노현송(Heyon-Song Noh) 박진운(Jin-Woon Park) 임홍식(Hong-Sik Lim)
• 간행물 정보: 『중독정신의학』Vol.5, No.1, 53~58쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2001.04.30

영문 초록

Objective：The purpose of this study is to determine whether glue-sniffing patients do have characteristics and brain dysfunction by event related potential P300. Methods：Subjects were composed of patients with substance abuse (glue-sniffing) (N=30) and normal controls (N=30). P300 was determined by standard methods, “oddball paradigm”. Results：In normal controls, P300 latency was from 264 msec to 384 msec (mean =306.00±28.71 msec). In patients with glue-sniffing, P300 latency was from 308 msec to 368 msec (mean=337.87± 15.38 msec). In patients with glue-sniffing P300 latency were more prolonged (p<0.001). In normal controls, P300 amplitude was from 1.56 uV to 13.54 uV (mean=5.82±3.12 uV). In patients with glue-sniffing, P300 amplitude was from 2.00 uV to 12.27 uV (mean=6.71±3.04 uV). There were no significant differences between the two groups. Conclusion：It is suggested that patients with glue-sniffing have different characteristics of P300 latency and brain dysfunction in some neurophysiological aspects.

키워드

Glue-sniffing Event related potential P300