망초 에탄올추출물의 항비만 및 항염증활성에 관한 연구

• 영문명: Conyza canadensis (L.) Extract Analysis of ingredients and anti-inflammatory anti-obesity activity
• 발행기관: 한국인체미용예술학회
• 저자명: 송현숙(Hyun Sook Song) 이거룡(Geo Lyong Lee)
• 간행물 정보: 『한국인체미용예술학회지』한국인체미용예술학회지 제18권 제1호, 231~241쪽, 전체 11쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2017.03.20

영문 초록

In this study, I measured the Anti-inflammatory and anti-obesity effect of the wild Conyza Canadensis plants native to Korea extracted from 70% ethanol in order to develop functional foods. I experiments with HEPG2 cells for figure out General ingredient & inhibitory effect of fat, 3T3-L1 cell for Adipogenesis inhibitory effect and anti-inflammatory effect with RAW264 cell, cytotoxicity test with HACAT cells. As a result, the contents of carbohydrates were 46.4%, 30.8% for crude fiber, 26.5% for crude protein, 16.3% for moisture, 9.5% for crude Ash and 1.2% for crude lipid so Carbohydrates content was the highest. In physiological activity, The highest effect is that Raw264.7 cells showed the 40% nitric oxide (NO) inhibitory effect at 25 ppm and 15% fat accumulation inhibitory effect at 50 ppm in HepG2 cells. In the case of 3T3-L1 cells, 25% inhibiting effect of lipid precursor cells was observed at 100 ppm. As shown in the results, the wild Conyza Canadensis extract is expected to have a high potential as a new functional material because it has abundant nutrients, anti-inflammatory activity and inhibitory activity of adipocyte.

목차

Abstract

Ⅰ. 서론

Ⅱ. 연구방법

Ⅲ. 결과 및 고찰

Ⅳ. 요약

참고문헌

키워드

망초 세포 독성 효능 산화 질소 지방 억제축적 안티 비만 horseweed(Conyza canadensis (L)) Cytotoxic efficacy NO(niric oxide) Inhibiting fat accumulation Anti-Obesity