고삼 에탄올과 열수추출물의 항산화, 항염증 및 항균효과

• 영문명: Antioxidant, antiinflammatory and antimicrobial activity of Sophora flavescens ethanol and hydrothermal extracts
• 발행기관: 한국인체미용예술학회
• 저자명: 문영주(Moon Young Ju) 김춘득(Kim Chun Dug)
• 간행물 정보: 『한국인체미용예술학회지』한국인체미용예술학회지 제18권 제1호, 91~103쪽, 전체 13쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2017.03.20

영문 초록

This study comparatively reviewed the antioxidant, antiinflammatory and anti-microbial effects of Sophora flavescens extracts. As a results of DPPH free radical, ethanol and hydrothermal extracts were 60.01% and 31.77%, respectively, at 500 μg/mL. Therefore, the former was higher in scavenging activity in a dependent fashion. Total polyphenol and flavonoid contents of the ethanol extract were 71.84 ±14.95 and 42.32 ± 1.05 μg/mL, respectively, while the hydrothermal extract was 61.20 ±2.35 and 35.80 ±4.79 μg/mL, respectively. Toxicity of ethanol extracts on HaCaT cells, no cytotoxicity was found at 10 μg/mL. In addition, concentration-dependent protective effects were verified for the oxidative stress caused by H₂O₂. Antimicrobial activity of ethanol extracts against skin flora such as Staphylococcus epidermidis, Staphylococcus aureus and Propionibacterium acnes were observed. a clear zone was observed in the ethanol strain. In Malassezia furfur, in contrast, antimicrobial inhibitory activity was detected in hydrothermal extracts as well. The said results show that the ethanol extract is greater than the hydrothermal extract in terms of antimicrobial, anti-inflammatory and antioxidant activities.

목차

Abstract

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

참고문헌

키워드

고삼 폴리페놀 플라보노이드 항산화 항균 Sophora flavescens Polypenol Flavonoids Antioxidant Antimicrobial