Impact of Metabolic Syndrome on the White Matter Integrity in Alzheimer’s Disease Patients : Tract-Based Spatial Statistics Study under 3-Tesla MRI

• 영문명: Impact of Metabolic Syndrome on the White Matter Integrity in Alzheimer’s Disease Patients : Tract-Based Spatial Statistics Study under 3-Tesla MRI
• 발행기관: 대한노인정신의학회
• 저자명: Hwagyu Suh Kangyoon Lee Young-Min Lee Je-Min Park Byung-Dae Lee Eunsoo Moon Hee-Jeong Jeong Young-In Chung Ji-Hoon Kim Hak-Jin Kim Chi-Woong Mun Tae-Hyung Kim Young-Hoon Kim
• 간행물 정보: 『노인정신의학』노인정신의학 제20권 제2호, 96~101쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2016.10.30

영문 초록

Objective：The aim of this study is to determine whether there is any difference in white matter (WM) integrity between Alzheimer’s disease (AD) with metabolic syndrome (MetS) and without MetS. Methods：Altogether, 30 subjects were finally recruited from the Memory Impairment Clinics of Pusan National University Hospital in Korea. All subjects (AD with MetS : n=15, matched AD without MetS for age, gender and year of education : n=15) were underwent 3-tesla magnetic resonance imaging scans of diffusion tensor imaging. Results：The mean fractional anisotropy of the AD with MetS was lower (p＜0.05) in right posterior corona radiate, right corticospinal tract and right superior longitudinal fasciculus than that of the AD without MetS. Conclusion：Our findings suggest that WM integrity damage.

목차

Introduction

Methods

Results

Discussion

키워드

Alzheimer’s disease Metabolic syndrome White matter integrity Diffusion tensor imaging