수면다원검사를 통해 분석한 소아 뇌전증환자의 수면장애

• 영문명: Polysomnographic Analysis of Sleep Problems in Children with Epilepsy: Influencing Factors in Sleep and Seizure Related Conditions
• 발행기관: 대한소아신경학회
• 저자명: 김애리(Aeree Kim) 이지원(Jiwon Lee) 주은연(Eun Yeon Joo) 이지훈(Jeehun Lee) 이문향(Munhyang Lee)
• 간행물 정보: 『Annals of Child Neurology(구 대한소아신경학회지)』대한소아신경학회지 제24권 제1호, 8~14쪽, 전체 7쪽
• 주제분류: 의약학 > 소아과학
• 파일형태: PDF
• 발행일자: 2016.03.30

영문 초록

Purpose: The objectives of this study were to identify the characteristics of sleep disorders in children with epilepsy complaining of sleep problems, and to find out sleep-related factors that influence on the prognosis of epilepsy. Methods: We retrospectively reviewed medical records and polysomnographic data of 94 children (mean age 13.7±3.8 years), who visited our hospital for epilepsy between March 2001 and December 2014. The patients were evaluated with polysomnography and a questionnaire about sleepiness. We compared clinical characteristics between patients with and without sleep disorders. We analyzed the differences of sleep parameters between the prognostic groups of epilepsy. Results: The patients enrolled in this study complained of various sleep problems, such as snoring, apnea, mouth-breathing, excessive daytime sleepiness, and insomnia. Sleep disorders were diagnosed in 46 patients (48.9%). Obstructive sleep apnea was the most common sleep disorder (n=26), followed by narcolepsy (n=8) and periodic limb movement disorder (n=8). Patients with poor prognosis showed decrease of stage 3-4 sleep (P=0.010). There was no significant correlation between the presence of sleep disorders and seizure control (P=0.053). Conclusion: Various sleep complaints and sleep disorders are commonly found in children with epilepsy. Polysomnographic analysis of patients with uncontrolled seizure indicates a decline in sleep quality. Screening sleep problems and performing diagnostic test with polysomnography in patients with sleep problems is recommended in pediatric patients with epilepsy.

키워드

Epilepsy Sleep disorder Polysomnography Prognosis Obstructive sleep apnea Narcolepsy