학술논문
Identification of a Novel Orally Active c-MET and RON Tyrosine Kinase Inhibitor for the Treatment of c-MET-or RON-Activated Solid Tumors
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- PARK Sook-Kyung LEE Eunyoung KI So-Young SHIN Hyun-Woo JUNG Won-Hyuk KIM Seung-Chan JUNG Soo Yeon JI Seung-Hee KIM SeungIn SONG Seog-Beom KO Dong-Hyun PARK Chi-Hye KIM Tae Won HONG Seung-Woo MOON Jai-Hee SHIN Jae-Sik JIN Dong-Hoon BAIK Taegon
- 간행물 정보
- 『추계총회 및 학술대회』(2014년), 227~227쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2014.10.24
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- Chemical Constituent of Pteris multifida
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- Establishment and Evaluation of Institutional Pharmacy Experimental Education
- Regulation of Angiogenesis and Vascular Function by miRNAs
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- Discovery of Novel Hsp90 Inhibitors and Evaluation of Their Antitumor Activities
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- Design and Synthesis of Isoquinolinoquinazolinones as Inhibitors of PPAR Gamma
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- Synthesis of a New Derivative of Xanthen-9-one-acetic Acid
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- Evaluation of 3-week Repeated Dose Oral Toxicity on Amomum tsao-ko Extract in Balb/c Mice
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- Concise Synthesis of (+)-Hyacinthacine A2
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- Isolation of Astrogorgin and Calicoferol Analogs Isolated from the Korean Gorgonian Astrogorgia rubra
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- The Hae-ae-tang, a Herbal Medicinal Prescription, Enhances Hair Growthin an Alopecia Animal Model of C57BL/6 Mice
- Inhibitory Effects of Polygala tenuifolia Willdenow on HCl·ethanol-Induced Gastritis in Rats
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- The Protective Role of Peroxiredoxin I in the Kidney of Cisplatin-injected Mice
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- New Anti-inflammatory Constituents from the Grains of Sorghum bicolor
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- Determination of a Novel Diacylglycerol Acyltransferase 1 Inhibitor, in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry and its Application to a Pharmacokinetic Study
- Strategy for the Configuration of Research Topics and Contents
- Anti-arthritis Effects of (E)-2-Methoxy-4-(3-(4 Methoxyphenyl) Prop-1-en-1-yl) Phenol Through Inhibition of STAT3 Pathway
- Pharmacometrics Applied to Translational Researches : Case Studies
- Salternamides A-D from Streptomyces sp. from a Korea Saltern
- Chemical Constitutents from Pinus thunbergii
- Effect of C-Phycocanin Isolated from Spirulina Extract on Modulation of Trans-Differentiation of Fibroblast to Myofibroblast
- Biotransformation of Testosterone by Resting Nocardioform Bacteria Rhodococcus equi
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- Efficacy Study of Remsima and Remicadeon Collagen-Induce Arthritis in DBA/1J Mice
- SC1 Suppresses Osteoclast Formation via Down-Regulating NFATc1
- Effect of Rutagraveolens L. on Osteoclast Differentiation and Bone Resorption
- Synthesis, Biological Evaluation and Structure-Activity Relationship of Quinazolinone Derivatives as Hedgehog Pathway Inhibitors
- In Silico Discovery of Novel Ligands for Helicobacter pylori KDO8P Synthase
- AlphaScreen-Based High-Throughput Screening Assay for Identification of IRAK-4 Inhibitors
- Acetyl- and Butyryl-cholinesterase Inhibitory Activities of the Edible Brown Alga Eisenia bicyclis
- Investigation on a Novel JNK Peptidomimetic Regulator
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- Anticancer Activity of Yuanhuacine in Non-Small Cell Lung Cells by Regulating AMPK/mTOR signaling and Actin Cytoskeleton
- Effects of Natural Products on Airway Mucin Secretion In Vivo and TNF-α-induced Activation of NF-κB Signaling Pathway Involved in the Gene Expression and Production of Airway Mucin In Vitro
- Plk1 Inhibitors Have Different Cellular Effects, Depending on the Targeting Domains of Plk1
- Beneficial Effect of Humulus Japonicus Extract on Hyperlipidemia and Fatty Liver Induced by High Fat Diet Obesity
- Relative Extent of Bioavailability Evaluation by Simultaneous Determination of Valsartan/Hydrochlorothiazide Complex Tablets : a Randomized, Single-Dose, Two-Period Crossover Study
- Gastroprotective Effect of the Traditional Herbal Medicine, Sipjeondaebo-tang Water Extract, Against Ethanol-Induced Gastric Mucosal Injury
- Effects of (-)-Sesamin on Chronic Stress Model in Mice
- Down-Regulation of MiR-96 May Mediate Multicellular Resistance to 5-FU in Tumor Spheroids Model
- CP2 Exhibits Potent Antitumor Effect in Non-Small Cell Lung Cancer Through Regulation of the LKB/AMPK/mTOR Pathway
- Modulation of Neurotoxicity Induced by L-DOPA Through the ERK-cJun in PC12 Cells
- Pharmacokinetic Profiles of Trifolirhizin, (-)-Maackiain, (-)-Sophoranone, and 2-(2,4-Dihydroxyphenyl)-5,6-Methylenedioxybenzofuran After Oral Administration of Sophora Tonkinensis Extract in Rats
- In Vitro effects of the Isolated Natural Compound, KJB-2, on the High Affinity IgE Receptor-mediated Mast Cell Activation
- New Triterpenoid Compounds Derived from Astilbe rivularis Enhance Glucose Uptake in C2C12 Myotubes via Akt and Erk1/2 Activation
- Anti-Atopic Dermatitis Effect of ScolopendrasinⅠin BALB/c Mouse Models
- Determination of Desmopressin in Human Plasma by LC-MS/MS: Application of Desmopressin ODF Formulation to a Pharmacokinetic Study in Healthy Male Korean Subjects
- An Aptide-Based Strategy for the Extension of Half-Life of Therapeutic Peptides
- Positive Effects of Danshensu on Pentobarbital-induced Sleep in Mice
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- Revision of NIER Test Guideline for Chemical Assessment: In Vivo Mammalian Erythrocyte Micronucleus Test
- Revision of NIER Test Guideline for Chemical Assessment: Carcinogenicity Studies
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- Comparison of Pharmacological Properties of Artemisia Annua L. with Different Extraction Processes
- The Role of Sestrin2 on TLR-mediated Acute Hepatitis
- The Biocompatibility of Nano-anticancer Drugs In Vitro
- Hyperphosphorylation of Tau in Brain in DAB-Treated Mice is Associated with Cognitive Impairment
- In vitro Carcinogenic Potential of Several Known Lung Carcinogens Using Balb/c 3T3 A31-1-1 Cell Transformation Assay
- RORα Activates the PGC1α-TFAM Axis that Causes Mitochondrial Biogenesis in Liver
- The Identification of Effect of Tyrosine Phosphorylated STAT3 Using Phosphorylation Specific Site Intrabody in Liver
- Cloning of Novel MicroRNAs from Human Mesenchymal Stem Cells
- Effects of Flavonoids on Senescence-Associated Secretory Phenotype Formation in Bleomycin-Treated BJ Fibroblasts
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- COT Activates Prolyl-Isomerase Pin1 to Enhance Breast Tumorigenesis
- Role of Flightless-I (Drosophila) Homolog in the Transcription Activation of Type I Collagen Gene Mediated by TGFb
- The role of SHP on Osteoclast formation
- Anti-inflammatory Effect of 1,7-substituted Methylxanthine Derivatives on Raw 264.7 and HK-2 Cells
- SUMO2 overexpression Enhances Generation and Function of IL-17-producing CD8+ T Cells
- Inhibitory Activity of a Novel Antibacterial Peptide Purified from Bacillus sp. YD1, Isolated from a Fermented Food
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- Prohibitin is a Host Partner of RtxA1 Toxin in Vibrio vulnificus Cytotoxicity
- CD8+ T Cells and Dendritic Cells Have Compensatory Role to Maintain Gut Immune Regulation in Functional Defect of CD4+Treg
- Euphorbia kansui Roots Inhibit the Differentiation of Naïve CD4+ T cells into Th17 T cells
- Molecular Design of Novel Agonists for Free Fatty Acid Receptors GPR40 as Antidiabetic Candidates
- Modification of 3-Arylisoquinolines into 3,4-Diarylisoquinolines and Assessment of Their Cytotoxicity and Topoisomerase Inhibition
- CCR5 Deficiency Increased Susceptibility to Lipopolysaccharide-induced Acute Renal Injury in Aged Mice
- Saponarin from Barley Sprouts Inhibits Adipogenesis of 3T3-L1 Cells by Peroxisome Proliferator-Activated Receptor γ
- Neuraminidase Inhibitory Activity and Inhibition Properties of Isolated Polyphenols from Korean Red Waxy Sorghum (Sorghum bicolor L. cv. Hwanggeum chalsusu)
- Design, Synthesis, and Evaluation of Topoisomerase Inhibitory Activity and Cytotoxicity of 2, 4-Diaryl-indenopyridine Derivatives
- Cytotoxic Activity of Neillia uyekii against Human Tumar cell Lines and Its Phytochemical Constituents
- The Methanol Extract from Tripterygium regelii Inhibits GPAT1 Enzymatic Activity and Suppresses de novo Triacylglycerol Biosynthesis through AMPK Activation
- Atractylochromene is a Repressor of Wnt/β-catenin Signaling in Colon Cancer Cells
- Pentacyclic Triterpenoids Isolated from Astilbe rivularis
- Quantification of Major Components from Cnidium officinale by HPLC-DAD
- Intracellular Killing Activity of Thymoquinone in Mycobacterium tuberculosis Infected Macrophages
- Simultaneous Chiral Separation of Several β-Blockers Using a Novel Combination of Dual Chiral Selectors in Capillary Electrophoresis
- Chalcones from Angelica keiskei Attenuate the Inflammatory Responses by suppressing Nuclear Translocation of NF-κB
- Structure Elucidation of the New Flavanone from Pentarhizidium orientale Roots
- N-in-1 PAMPA Assay for Membrane Permeability Screening
- Relation between a Partition Coefficient and Solvent System Composition: Separation of Triterpenoid Saponins from the Roots of the Bupleurum falcatum by Countercurrent Chromatography
- Determination of Plasma Omega Fatty Acids in Asthma Patients and its Correlation
- Fundamental Study for the Generating High Efficiency Slightly Acidic Electrolyzed Water(SAEW) inNon-Membrane Electrolytic Cell
- Development of Quantitative and Qualitative Method for the QualityControl of Cassiae Semen by HPLC
- Quantitative and Qualitative Analysis of KJ001 by HPLC-UV and LC-ESI-Mass Spectrometry
- Determination and Validation of Hyaluronic Acid in Dietary Supplement by HPLC-UV
- Preparation and Physicochemical Characterization of Mouthwash Granules Containing Mentol, Thymol, Eucalyptol and Methyl salicylate
- A Development of Histone H1-specific Aptide as a Novel Apoptotic Imaging Probe
- Characteristics and Preformulation of Extracts Obtained from Aesculus hippocastanum L.
- Preparation and Characterization of Taste-masked Microspheres Containing Azithromycin by the Solvent Diffusion Method
- LC-ESI-MS/MS assay for the Determination of Benzyl Butyl Phthalate and Its Major Metabolites, Monobenzyl Phthalate and Monobutyl Phthalate, in Rat Plasma
- Pharmacokinetic Study of Enzalutamide in Rat by Liquid Chromatography – Tandem Mass Spectrometry
- An Exploratory Study on Firm's Drug Production Behavior and Financial Profits in South Korea
- Pharmacokinetic Comparison Study of a Combination Containing 500 mg of Naproxen And 20 mg of Esomeprazole: a Randomized, Single Dose, 2-way Crossover, Open Label Study in Healthy Male Korean Subjects
- Utility of Breakthrough Therapy Designation Pathway and Its Applicability to Korean Pharmaceutical Environments
- The Impact of Vancomycin Minimum Inhibitory Concentrations on the Clinical Outcomes in Obese Patients with Methicillin-Resistant Staphylococcus aureus Isolates from a Pulmonary Site
- Evaluation of Preceptor and Students for Community Pharmacy Practice
- An Analysis of APIs Purchasing Pattern Before and After Price Cutting of Drugs - Focusing on Policy of Overall Price Cutting of Current Drugs dated April 1, 2012 -
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- The Impact of a Strong CYP2D6 Inhibitor on the Pharmacokinetics of Tolperisone in CYP2C19 Poor Metabolizers
- The inhibitory Effect of Gooseberry on Atopic Dermatitis in Vivo and in Vitro
- Pancreatic Lipase Inhibitory Phthalide Derivatives from the Rhizomes of Cnidium officinale
- Drug-Interaction of Herbal Medicine; Toxicological review
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- Drug-Herb Interaction in the Aspect of Clinical Pharmacology
- Targeting Sphingolipid Biosynthesis by Myriocin Arrests G2/M Phase in Melanoma Cells
- Tobacco Carcinogen-Induced RTK Signaling is Regulated via GPCR Signaling
- Pharmacokinetics of YJC-10592, a New Chemokine Receptor 2 (CCR-2) Antagonist, in Rats
- High-Throughput Screening of Cytochrome P450 Induction Using luminogenic Assay
- Prolyl Isomerase Pin1 Regulates Adipocyte Differentiation through PPAR Gamma Regulation
- Quercetin-3-O-Glucuronide Increases Neural Stem Cell Proliferation
- The Impact of a Moderate CYP2C9 Inhibitor on the Pharmacokinetics of Meloxicam
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- Inhibition of TNF-α-Induced Adhesion Molecule Expression by Lobastin in Mouse Vascular Smooth Muscle Cells via Downregulation of p38, ERK and NF-κB Signaling Pathways
- Morin Potentiates the Effect of a β-Lactam Antibiotic Against Methicillin-Resistant Staphylococcus Aureus
- Inhibitory effect of Tricyclic Antidepressant (Amitriptyline) on Electrical Field Stimulation (EFS) Induced Colon Muscle Contraction
- Dietary Supplementation with a Fermented Barley and Soybean Mixture Attenuates UVB-Induced Skin Aging and Dehydration in Hairless Mouse Skin
- AMP-Activated Protein Kinase Inhibitor Compound C Inhibits Adipocyte-Mediated Macrophage Chemotaxis Through Targeting AKT-FAK Pathway
- Effects of Ginkgo Biloba Extract on Steroid Sulfatase in Various Cells
- The Cardiac Safety and Antitumor Profiles of Aurora Kinase Inhibitor ZM447439
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- Block of Nav1.7 Sodium Current by Chlorpromazine
- Selective Inhibition of HDAC6 Regulates Preferential Cytotoxicity in Cancer Cells by Modulating p53 and Hsp90 Stability
- Comparative Proteomic Analysis of Kidney from Adult Cloned Pig Using LC-MS/MS
- Inhibitory Effect of D-chiro-inositol against Human Breast Cancer
- Hydroxylated 2, 4-Diphenyl Indenopyridine Derivatives as a Selective Non-intercalative Topoisomerase II Catalytic Inhibitor
- Antiviral Activity of Manassantin B against Human Enteroviruses
- Total Synthesis of Broussonone A
- New Polycyclic Antibiotics from a Wetland-derived Marine Actinomycete
- Antifibrotic Constituents of Liriodendron tulipifera Attenuating HSC-T6 Proliferation and TNF-a Production from RAW264.7 Macrophages
- Natural Product-derived Polyacetylenes Regulate the Adipogenesis and Inflammation
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- Isolation and Characterization of Quercetin Glycosides from Dendropanax morbifera
- Analysis of Ginsenosides in Different Types of Ginseng by using HPLC with Charged Aerosol Detector (CAD)
- Initial Preclinical Safety of Non-Replicating Human Endogenous Retrovirus Envelope Protein-Coated Baculovirus Vector-Based Vaccines
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- Formulation, Characterization and Physicochemical Evaluation of Melissa officinalis L. leaves Tablets
- Hyaluronic Acid-Coated Solid Lipid Nanoparticles for Targeted Delivery of Vorinostat to CD44 Overexpressing Cancer Cells
- Preparation and Evaluation of Supercritical Ffluid-mediated Liposomes Containing Cyclosporin A for Dry Eye Syndrome
- Application of Quality by Design(QBD) to the Optimization and Preparation of Telmisartan Self-Microemulsifying Drug Delivery System(SMEDDS) Formulation
- CurrentIssues of Pharmaceutical Serialization and Traceability in the Korean Medicine and Medical Supplies
- Evaluation of Using Pattern of the Topical Drugs Including Steroid in Community of Korean
- Comparison of Satisfaction Levels on the Provision of Medication Education between Patients and Pharmacists
- The Machanism of Torilin in Antimelanogenesis
- Simultaneous Determination of Sarpogrelate and Its Active Metabolite, M-1, in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Pharmacokinetic Study
- The Influence of a CYP2C19 Inhibitor on the Pharmacokinetics of Tolperisone in Relation to CYP2D6 Genotype
- The Current Status of KCB Chemical Library and DB
- Inhibition of E2F3 by miR-199a-5p in Mesenchymal Liver Tumor: Anti-tumor Effect of Potoporphyrin Ⅸ
- New Inhibitors as Potential Anticancer Agents in Human Breast Cancer Cell
- Challenge and Opportunity of Drug Development in Diabetes and Obesity
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- A Lithium Naphthalocyanine Derivative as an Oxygen Sensor in the Isolated Beating Heart and its Potential in Vivo Use
- Emergent Strategy for Academy-Industry Cooperation
- IP-R&D Strategy for Creating a Strong Intellectual Property
- Establishment and Evaluation of Pharmaceutical Industrial Pharmacy Education
- Dong Hwa Pharm, One Hundred Years Dedication to Pharmaceutical Industry in Korea
- Establishment and Evaluation of Pharmacy Administration Practice
- Neuroprotective Effect of SK95, a Proteasome Activator, against MPP+-Induced Cell Death
- History of Pharmacy Education Eligibility Test (PEET)
- A Study on Neurotoxicity and Psychological Dependence of Synthetic Cannabinoids
- Inhibitory Effect of a Novel Carbazol Derivative (EJCa15) on Platelet-Derived Growth Factor-Induced Migration and Proliferation of Vascular Smooth Muscle Cell
- Anti Pruritic Effects of Belamcanda chinensis in ICR Mice
- Cytotoxic Effects of Salvia miltiorrhiza BUNGE Extracts on Human Cancer Cell Lines
- Effects of Berchemia Berchemiaefoliae (Mak.) KOIDZ Roots on Immobile Behavior and Anti-Depressive State in the Forced Swimming Test
- Mitochondrial DNA Copy Number Alterations in Gatric Cancer Tissues and Cell Lines
- Design and Synthesis of Azaisoflavone Analogs as Phytoestrogen Mimetics
- Divergent Synthesis of Jatamanins
- Carbazole and Their Derivatives; Synthesis and Evaluation as Inhibitor of the Platelet Aggregation
- Neuroprotective Effects of Spinosin, a C-glucosylflavone from Zizyphus jujuba var. spinosa, on Aβ1-42 Oligomer-induced Mouse Model of Alzheimer’s Disease
- Introduction of MFDS Herbal Reference Standards(HRS) and Its Re-test System
- EGFR-Targeting Immunoliposomes with Fisetin for Colon Cancer
- Green Synthesis of Gold Nanoparticles by Caffeic Acid and Their Role as a Catalyst toward 4-Nitrophenol Reduction
- Comparative Dissolution Test of Poorly Water-Soluble Fenofibrate Solid Dispersion
- Good pharmaceutical Care Practice Beyond Good Pharmacy Practice
- Basic Requirements of Patentability & Patent Examination Process
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