학술논문
A novel PPAR pan agonist MHY2013 improves insulin-resistance and dyslipidemia in db/db mice
이용수 8
- 영문명
- 발행기관
- 대한약학회
- 저자명
- AN Hye Jin PARK Min Hi LEE Bong Gi JEONG Hyoung Oh KIM Dae Hyun LEE Eun Kyeong CHUNG Ki Wung MOON Kyoung Mi KIM Ye Ra JEONG Ji Won PARK June Whan MOON Hyung Ryoung CHUNG Hae Young
- 간행물 정보
- 『춘계총회 및 학술대회』(2015년), 540~540쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2015.04.24
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- Identification of in vitro noninvasive biomarkers for nephrotoxicity by proteomic analysis
- Molecular modeling & synthesis of b-raf inhibitor
- Affirmative impact of herbal medicine for various respiratory symptoms
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- PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice
- Identification and Characterization of Aroma Compounds in Cudrania tricuspidata (Carr.) Burea
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- Enhanced biovailability and lymphatic delivery of paclitaxel-loaded lipid nanocapsules
- Synthesis, characterization and biological evaluation of oxadiazole derivatives bearing 5-phenyl-tetrazole as osteoclast differentiation inhibitors
- Toxicity assessment of elemol from Chamaecyparis obtusa essential oil
- Effect of a Herbal Preparation (HemoHIM) on the Maturation of Bone Marrow Derived Dendritic Cells
- Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome for steatohepatitis
- Globular Adiponectin Causes Tolerance to LPS-induced TNF-α expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of ROS/FoxO3A Axis
- PTP1B inhibitory constituents from the aerial parts of Tradescantia spathacea Sw
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- Evaluation of gastric motility activity of the extracts and isolates from traditional medicinal herbs
- Synthesis and biological activity of tricyclic derivatives containing a phenyl ring
- Population pharmacogenetic pharmacokinetic modeling for flip-flop phenomenon of entericcoated mycophenolate sodium in kidney transplant recipients
- Metabolomic profiling of valproic acid-induced rat model of autism spectrum disorders using 1H NMR spectral analysis
- Coumarins from Angelica decursiva inhibit lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells
- (-)-Menthol and related compounds in peppermint as testosterone 5α-reductase inhibitors
- Secondary metabolites of the aerial parts of Eclipta prostrata
- Two new compounds from the grains of Echinochloa utilis (Barnyard Millet)
- Pomolic acid inhibits invasion of breast cancer cells through the suppression of CXC chemokine receptor type 4 expression
- Green gold nanoparticles synthesized using earthworm extracts and the reinforcing effect on anticoagulant activities of heparin
- Effect of snail extract extract on chondrotin sulfate administration on growth increment, blood IGF-1, IGFBP-3 concentration in growing and old rats
- Chemical constituents from the leaves of Dryopteris erythrosora
- Development of physiologically based pharmacokinetic model of benzyl butyl phthalate and its active metabolite mono benzyl phthalate in rats
- A study on cardioprotective activity of ginsenoside-Re in ischemic damage
- Protective effect of Rhei Rhizoma on reflux esophagitis in rats through suppressing oxidative stress and inflammation
- Picroside II extracted from Pseudolysimachion longifolium suppresses MUC5AC expression via downregulating p38/ERK MAPKs and modulating transcription factors in NCI-H292 human lung mucoepidermoid cells
- Glucocorticoid- and long-term stress-induced aberrant synaptic plasticity are mediated by activation of the glucocorticoid receptor
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- Hepatoprotective Effect of Limonium tetragonum Extract Following Acute Alcohol Intoxicity in Rats
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- Phenolic compounds from Salicornia herbacea
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- Promising anti-diabetic potential of capillin and capillinol isolated from Artemisia capillaris
- Antiapoptotic effect of ginsenoside Rb1 against homosysteine on endothelial progenitor cells
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- A polymeric colon-specific prodrug releasing 5-ASA and benzocaine ameliorates TNBS-induced rat colitis
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- Synthesis of novel 4′ α -trifluoromethyl-2′ β -C-methyl-carbodine analogs as anti-hepatitis C virus agents
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- Antioxidant effect of Selenigella tamariscina methanol extract on impairments induced by scopolamine in rats
- In vitro simulation of food effect on dissolution of BCS class III drug: The correlation of in vitro dissolution and in vivo absorption
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
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- De novo design of doubly-stapled helicalpeptides as antimicrobial agents
- Anoctamin1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia
- Effects of scolopendrasin I, a novel peptide on atopic dermatitis in NC/Nga mice model
- Inhibitory effect of a sesquiterpine from Schisandra chinensis on an ovalbumin-induced asthma model
- Potentiation of ΔF508- and G551D-CFTR-mediated Cl- current by novel hydroxy pyrazolines
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- Genetic Inhibition of Tyrosine Hydroxylase Potentiates Methamphetamine-Induced Neurotoxicity
- Shear stress enhances Ca2+ spark occurrence in rat ventricular myocytes via the activation of NADPH oxidase
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- Intramuscular administration of novel SLNs-loaded dual-reverse thermosensitive nanomicelle with sustained release and reduced toxicity
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- Korean red ginseng inhibits myocardial toxicity by doxorubicin
- Molecular modeling & synthesis of 11β-hydroxysteroid dehydrogenase type 1 inhibitor
- Drug repositioning: from anti-malarial drug to anti-obesity drug
- Catalase protects high-fat diet-induced early liver injury
- Antitumor activity of myriocin, a sphingolipid biosynthesis inhibitor, and its mechanism in melanoma mice
- Exogenous 8-oxo-dG prevents high fat-induced liver injury through enhancing mitochondrial biogenesis
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- Comparison on tooth stain prevention effect of SAPP-contained mouthwash and others
- The inhibitory effect of SMB-6 on Rotenone induced endoplasmic reticulum stress and cell death in SH-SY5Y cells
- Signal transduction underlying the inhibitory mechanism of Fluoxetine on Electrical field stimulation response in rat ileal smooth muscle
- IL-4 mediated suppression of tumor development via activation of STAT6 in melanoma model
- Activation of NOX2 induces invasive phenotype in colon cancer cells through overexpression of MMP-7
- Delayed treatment with fenofibrate protects against high-fat diet-induced kidney injury via the AMPK-autophagy axis
- Prognostic gene signatures in pediatric medulloblastoma
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- Species difference elucidation of 11β-hydroxysteroid dehydrogenase 1 through ensemble and induced fit docking studies
- Effect of the Conformational Restrictor in Benzamidochromenone derivatives for the inhibition of Interleukin-5
- Identification of inhibition modality of novel inhibitors for pim kinases using a fluorescence polarization assasy
- AME is a Mammalian Target of Rapamycin kinase inhibitor on EGF-induced neoplastic cell transformation
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- Chemical stability of bis-retinamido methylpentane, a novel hybrid retinoid derivative, and its in vitro and clinical efficacy
- Nitric oxide-releasing chitosan films for enhanced antibacterial activity and in vivo wound healing efficacy
- Quantitation of Biflorin in rat plasma by liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies
- In vitro skin permeation of disodium phenyl dibenzimidazole tetrasulfonate using Franz diffusion cell method
- Tacrolimus-encapsulated porous poly(lactic-co-glycolic acid) microspheres for treating bleomycin-induced pulmonary fibrosis
- Synthesis of Antifungal Evaluation of 2H-[1,2,3]Triazolo[4,5-g]isoquinoline-4,9-diones
- Pathogenesis-related proteins (PRP) from a dropwort play a role in regulating toll-like receptor-dependent downstream signal pathway
- Improved pharmacokinetics and brain delivery of resveratrol from N-Trimethyl chitosan-g-palmitic acid surface modified solid lipid nanoparticles
- Potentiated toxicity of multiple exposure to phthalates
- Inhibition of iNOS and cytokine induction by specific oligopeptides in fermented soybean extract from Glycine max
- Development and Evaluation of New Immediate-Release Dosage Form for Complex Migraine
- Chemical evaluation of marine sponge extract
- Strengthening immunity against influenza H1N1 virus by Morusalba L. fruit
- Chemotherapeutic potential of Hsp90 and biological evaluation of a novel Hsp90 inhibitor
- Requirements to be considered in the LIMS optimization process
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- The Patents of material, the beginning of a new opportunity
- Process control strategy in biopharmaceutical manufacturing
- New alkaloids from roots and rhizomes of Veratrum nigrum L.
- Dual characterization of electroosmotic volume flow through skin and the modulation of ketoprofen flux using polyethyleneimine
- Dose-independent ADME properties and tentative identification of metabolites of a-mangostin from Garcinia mangostana in mice by automated microsampling and UPLC-MS/MS method
- Discovery of microRNA as a potential biomarker for colorectal cancer metastasis
- Visible light-induced perfluoroalkylations
- Steroid sulfatase induces epithelial mesenchymal transition (EMT) through HIF1a induction in human prostate cancer cells
- Dapoxetine decreased the excitability of small dorsal root ganglion neurons
- Optimization of oligonucleotide synthesis using DOE Study
- Oxazolone as a useful synthetic tool for amidation of aminoisobutyric acid
- Facile and simple functionalization of gold and silver nanoparticles with ampicillin
- Flavonoid constituents from n-butanol fraction of the aerial parts of Agrimonia pilosa Ladeb
- Interspecies pharmacokinetic scaling of FL-05 based on animal data
- Connecting the present and the future, Hanmi's R&D strategy
- Efficient siRNA delivery system using dendritic gold nanoparticle
- Design and synthesis of 1,2,3,4-Tetrahydroquinoline-2-carboxylic acid N-(substituted) phenylamide derivatives as potential NF-kB inhibitor
- Studies on the mehanism of inhibition of serum and glucocorticoid-inducible kinases (SGKs) by a pyrrolopyridine derivative
- Injectable biomaterials for the treatment of vocal fold disease
- The role of tauroursodeoxycholic acid on stem cells for bone tissue regeneration
- Methionyl-tRNA synthetase (MRS) controls CDK4 stabiltiy in p16INK4a negative cancer
- Understanding and utilization plan of the product approval and patent linkage system – in the product patent viewpoint
- Alzheimer disease and treatment
- Pharm-retail on healthmarket, O2O methodology with Retail 3.0
- Advancement of pharmacy management and case
- Stability of glutamate carboxypeptidase II, a glutamate synthesizing enzyme, is regulated by acetylation
- Promotion criteria for clinical faculty in US pharmacy schools
- Biological effects of phenolic compounds isloated from marine algae
- State-of-the art characterization of biopharmaceuticals for QC/QA using advanced mass spectrometry
- Analysis of the mission and goal of pharmacy education
- Pharmaceutical care service, a crucial sector in national healthcare system
- The Impact of Pharmacist-Initiated Interventions ImprovingAcute Coronary Syndrome Secondary Prevention
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- MFDS biopharmaceutical quality and pharmacovigilance policies
- Bidirectional actions of hippocampal Zn2+ signaling in cognition: its involvement in amyloid-β-induced cognitive decline
- Glutathione peroxidase 1 deficiency attenuates Concanavalin A-induced hepatic injury by modulation of T-cell activation
- Development of laboratory monitoring alert system of hyperkalemia related to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
- Modified delivery of axitinib that are nanohybrid liposomal nanoparticles effects on hypoxic tumor growth
- Resveratrol-mediated green-synthesis of gold and silver nanoparticles and their in vitro antibacterial activity
- Chromatographic enantiomer separation and determination of chemical and optical purity of α-amino acids and methyl esters as fluorenylmethoxycarbonyl derivatives with fluorescence detection
- Pharmacokinetic study in disease animal model
- A pharmacokinetics study of drug-drug interaction between 5-fluorouracil, irinotecan and BST204, a purified ginseng dry extract, after interavenous and intraperitoneal injection administration to rats
- Effects of scutellarein, a flavonoid of Scutellaria lateriflora, on inflammatory responses
- Involvement of mTOR signaling pathways in the neuroprotective effect of Eleutherin against the glutamate-induced hippocampal cell damage, mimicking severe Alzheimer’s disease brain condition
- siRNA-ligand conjugate system for targeted delivery
- Effect of 18:1 lysophosphatidylethanolamine on intracellular Ca2+ concentration through GPCR in neuronal cells
- Duel function of a novel compound E on platelet-derived growth factor-induced vascular smooth muscle cells
- Prenatal toll-like receptor-2 activation induces social and cognitive problems in female mice
- Enrichment of cells with high-level protein expression by destabilization of selection marker
- Protective effect of 8-oxo-2'-deoxyguanosine in high fat-fed mice kidney
- Chrysin enhanced the therapeutic efficacy of docetaxel in non-small cell lung cancer
- Preclinical assessment of toxicity and toxicokinetics of piroxicam after intra-articular injection in normal rats
- Genetic mechanisms for association between tobacco smoking and allergy
- Rdiation induced cancer risk assessment via dietary exposure
- Inhibitory effect of Hinokitiol on adipogenesis in 3T3-L1 preadipocytes
- Kaaempferol suppresses collagen-induced platelet activation through inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation
- Flexibility of β-arms of HU from Staphylococcus arueus dictates the DNA binding and recognition mechanism
- Role of Adiponectin in the pathogenesis of Alzheimer’s disease
- The prolyl isomerase pin1 interacts with a 90kDa ribosomal protein S6 kinase 2 to enhance TPA-induced cell transformation
- Role of moesin in HMGB1-stimulated severe inflammatory responses
- Autophagic dysregulation by altered expression of novel autophagy regulators in Parkinson’s disease model
- The interaction between Notch-1 and HIF-1α promotes ischemic neuronal death
- YP754 inhibits adipocyte differentiation via downregulation of PPAR-gamma in adipocytes
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- A novel PPAR pan agonist MHY2013 improves insulin-resistance and dyslipidemia in db/db mice
- Anti-osteoclastogenic activity of p38 inhibitor doramapimod via inhibiting migration of pre-osteoclasts and NFATc1 activity
- Repositioning potential of PAK4 to osteoclastic bone resorption
- Eukaryotic translation initiation factor, eIF2S2, promotes cell growth and migration in human cervix carcinoma cells
- Methanol extracts of Xanthium Sibiricum roots inhibit the inflammatory responses via the inhibition of NF-κB and STAT3 activation in murine macrophages
- Phaseollin inhibits endotoxin-induced inflammation in murine macrophages
- Solanum tuberosum L. cv Hongyoung extract inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice
- Increase of CCR7-dependent dendritic cell migration to lymph node by glucans
- Animal models for preclinical efficacy evaluation of stem cell therapy
- Rosmarinic acid inhibition of HIF-prolyl hydroxylase is potentiated by lipophilic modification of the natural product
- Target identification of thienopyrimidine derivatives by a chemical biology approach
- Studies on Phytochemical Constituents from Nandina domestica
- Heat-processing of Corni Fructus enhances renoprotecive effect on cisplatin-induced acute kidney injury in mice
- Attenuant Effects of Hydroponic-cultured Ginseng leaf extract on inflammatory collagen-induced arthritis in Rats
- Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced beta-cell damage and the development of type 1 diabetes
- Metabolism of evogliptin in human hepatic preparation
- Determination of the free thiol-containing antitumor agent, mertansine, in rat plasma by LC-MS/MS and its application to pharmacokinetic study
- Multiresidue method for the quantitation of 20 pesticides in aquatic products
- Role of cytochrome P450 and UDP-glucuronosyltransferases in metabolic pathway of homoegonol in human liver microsomes
- Method Development of NBOMes in Oral Fluid by Solid Supported Liquid Extraction and Gas Chromatography Mass Spectrometry
- Formulation,characterization and physicochemical evaluation of Melissa officinalis L. leaves tablets
- Sustained release Melt Extruded formulations using Eudragit RSPO and RLPO and content uniformity by FT-IR chemical imaging
- Pharmacokinetic comparison of a microgranule formulation with a tablet formulation of Desmopressin in Healthy Korean Subjects: A randomized, open-label, single-dose, 2-period crossover study
- Continuous twin screw granulation and powder rheological characterization of dry granules containing levetiracetam
- Development and evaluation of orally disintegrating tablet by inclusion complex
- In vitro and in vivo characterization of novel anti-AMF human monoclonal antibody for cancer therapy
- Particle design and in vivo evaluation of Eudragit E nanoparticle containing dutasteride
- Preparation of taste-masked solid dispersion containing palonosetron hydrochloride and evaluation of taste-masking efficiency using E-tongue
- The degradation profile and pH stability of Tenofovir Disoproxil
- Application of physiologically based pharmacokinetic (PBPK) modeling in prediction of pediatric pharmacokinetics
- Population pharmacokinetic modeling of midazolam in healthy volunteers : evaluation for drug-drug interaction
- Application of Advanced Compartmental Absorption and Transit model for prediction of human pharmacokinetic(PK) profile uisng preclinical in-vitro and in-vivo studies
- Effects of regulatory nuclear receptor (CAR, HNF4α and PXR) genetic polymorphisms on stable warfarin doses in patients with mechanical cardiac valves
- Oxidative C7-Acylation of Indolines with Aldehydes or Alcohols under Palladium Catalysis
- Two new lignans from the Fruits of Schisandra chinesis(Turcz.)Baill
- The Improving effect of Cucumis melo on atopic dermatitis in vivo
- Eriobotryae Folium improved inflammatory response through an oxidative stress and advanced glycation endproduct-meidated pathway in the liver of type 2 diabetic db/db mice
- New cytotoxic sesquiterpenoids from siegesbeckia glabrescens
- Taming the chemical reactivity and selectivity : Known and unknown paths (and somewhere between)
- Effects of AGS to stress caused by climate change
- Protective effects of Phosphatidylcholine on Oxaliplatin-induced neuropathy in rats
- Evaluation of questions from Cybercondriacs related to drug information and suggestion of providing evidence-based answer
- In-vitro study of Novel Active Ingredient for Dentin Hypersensitivity Toothpaste
- PEGylation effect of poly(amidoamine) dendrimers on cytotoxicity in hippocampal neuronal cells
- Synthesis and Biological Evaluation of Chemical Probes Targeting Hypoxia-Inducible Factor (HIF)-1α/ Malate Dehydrogenase 2
- Effects of geniposide on hepatocytes undergoing epithelial-mesenchymal transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways
- Society’ s eyes looking at the pharmacist community and The need for talent of consilience type
- Metabolomic application for MS based flavonoid research
- Cellular regulation of polyphenols compounds in cancer
- A friendly health communicator with professional qualification
- Prospectives of the clinical pharmacy education
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- A large-scale synthesis of self-assembled DNA nanostructures by rolling circle amplification for delivery of siRNA conjugates
- Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl) phenol Isolated from Butanol Fraction of Cordyceps bassiana
- Para-methoxymethamphetamine (PMMA) induces neurotoxicity and memory impairments in mice
- Characterization of the auditory electrophysiological responses in rat with salicylate-induced tinnitus
- P47phox plays a critical role in the apoptosis and reactive microgliosis induced by methamphetamine
- IRAK4 as a therapeutic target of innate immunity-imbalanced acute liver injury by chlorogenic acid
- Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter via nuclear receptor ERRγ in SH-SY5Y cells
- Anti-inflammatory Activities of Gouania leptostachya Methanol Extract and its Constituent Resveratrol
- Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice
- CYP2D6 genetic polymorphism significantly affects pharmacokinetics of Tolterodine
- The stereoisomers of crizotinib differentially induce change in the morphology of cancer cells
- Development of reactive metabolite screening system using human liver microsomes and LC-MS/MS
- Radiation human exposure and cancer risk assessment in cosmetics
- Evaluation of chemosensitivity using patient-derived xenograft model
- Ginseng total saponins induces the cardioprotection against ischemia/reperfusion injury
- Induction of integrin signaling by steroid sulfatase metabolism in HeLa cells
- A ring-truncated deguelin analogue induces apoptosis and anti-angiogenesis in non-small cell lung carcinoma cells
- Effects of apigenin and synthetic flavones on senescence-associated secretory phenotype in bleomycin-induced senescence in BJ fibroblasts and in vivo aged rats
- Cristacarpin inhibits endotoxin-induced inflammation in murine macrophages
- Anti-inflammatory effects of Crataeva nurvala Buch. Ham. Are mediated via inactivation of ERK but not NF-κB
- Contribution of the CD24 polymorphism to autoimmune disease: A meta-analysis
- Apatinib in HSA-PEG inhibits VEGF-induced retinal vascular permeability
- Selective C–H Cyanation of Indolines and Indoles with Easily Accessible Cyano Source under Rhodium Catalysis
- Selective C–H Allylations of Indolines and Indoles with 4-Vinyl-1,3-Dioxolan-2-One under Rhodium Catalysis
- Chiral separation of evodiamine in the biological sample by HPLC
- Pharmacokinetics and therapeutic efficacy of piroxicam, a long acting non-steroidal anti-inflammatory drug, after intra-articular injection in osteoarthritis-induced rats
- Structure ensemble based virtual screening discovered new inhibitors of tyrosinase
- Preparation and evaluation of oral disintegrating film containing local anesthetic agent, Lidocaine
- Determination of drometrizole trisiloxane by LC-MS/MS and application to an in vitro dermal absorption study
- The Misuse or Abuse of Stimulant Medications for Attention-Deficit/Hyperactivity Disorder (ADHD) in Adolescents and Adults
- Acerogenin A, a natural compound isolated from Japanese folk medicine Acer nikoense Maxim, prevents oxidative stress-induced neuronal cell death through Nrf2-mediated heme oxygenase-1 expression
- The potent medicinal plants, species of Lycopodiopsida, as a therapeutic agent for non-alcoholic fatty liver disease
- 4-Isopropyl-2,6-bis(1-phenylethyl)aniline 1 originated from Cordyceps bassiana has anti-inflammatory activities in macrophages
- Development of standard criteria for the quality evaluation of The Gentianae Macrophyllae Radix by TLC and HPLC
- Influence of MRP2 C24T genetic variant on the pharmacokinetics of Valsartan
- Alleviation of ischemia and reperfusion-induced liver injury by SPA0355
- Increased neural stem cell proliferation by quercetin-3-O-glucuronide
- Preparation and physicochemical characterization of cocrystal comprising celecoxib and tramadol hydrochloride for improved intrinsic dissolution rate
- Stereoselective total synthesis of 1-deoxygalactonojirimycin and research on total synthesis of 1-deoxyidonojirimycin via chiral 1,3-Oxazine
- Repositioning of Prickly Pears grown in Jeju Island for treatment of perimenopausal symptoms
- Drug development targeting Pin1-catalyzed conformational changes in cancer and Alzheimer’s Disease
- Beneficial effects of Humulus japonicus extract on hyperlipidemia and fatty liver induced by high-fat diet obesity
- Anti-cancer effect of (E)-4-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol on colon cancer cell growth by activation of DRs and inhibition of STAT3/NF-κB pathways
- Genetic inhibition of ceruloplasmin potentiates neurotoxicity induced by kainate
- Mitochondrial alteration and AMPK activation in NRF2-silenced human cancer cells
- Distribution of CYP2C19*10 allele in a Korean population
- Neuroprotective effects of WSY against lipopolysaccharide-induced neuronal damage
- 15-deoxy-Δ12,14-prostaglandin J2-induced cell apoptosis through ROS-mediated mechanism in gastric cancer cells
- In vitro activity of (-)-deoxypergularinine against Mycobacterium tuberculosis strains
- Potent and selective inhibition of sarpogrelate and its active metabolite, M-1, on the Human UDP-glucuronoslytransferase 1A4 activity
- Hydroquinone suppresses expression of IFN- β via AKT regulation
- Citrus unshiu peel extract protects cultured rat cortical neurons from beta amyloid-induced neurotoxicity
- Neuroprotective effects of labm99 on ischemia/reperfusion injury through inhibiting ASK1-JNK-p38 signal pathway
- Cordyceps pruinosa Buthanol fraction exhibit anti-inflammatory effect by suppressing of NF-kB activation
- 5-Aminosalicylic acid activates AMPK: an implication in anti-colitic activity of the anti-inflammatory drug
- Sphingosine-1-phosphate induces c-reactive protein via C/EBPβ and potentiates breast cancer progression
- Studied on inducing hair restoration of synthetic Oleanolic acid derivatives
- The comparison of health behavior by taking antihypertensive drugs in community pharmacy care service
- Organic anion transporter 3-mediated transport of verproside
- A multi-class analytical method for screening and confirmation of veterinary drug residues in fishery products based on liquid chromatography coupled to tandem mass spectrometry
- Preparation of chitosan coated alginate-Bee Venom nanoparticles
- Facile and Inexpensive microfluidic array chips for the detection of DNA/RNA pathogens
- Quantitative analysis of sphingomyelin by high-performance liquid chromatography after enzymatic hydrolysis
- Anti-inflammatory effects of fisetin by inhibition of Src and syk kinase activity
- In vivo gastroprotective effect along with pharmacokinetics, tissue distribution and metabolism of isoliquiritigenin in mice
- Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25-35 neurotoxicity
- Inhibitory effects on gstric lesions of Genipin
- Nrf2 regulates AhR activity, which contributes to cell survival
- Trp250-hK2 is defective in intracellular trafficking and actives the unfolded protein
- Ameliorative effect of caffeic acid cyloheylamide on protein kinase IKK-β- dependent immune-mediated early sepsis and liver injury
- Wound healing effect of the butanol fraction from Hydnocarpi Semen crude extract in ulcer injury of mice
- Two acidic amino acids, E143 and E705, contributes to calcium-dependent gating of Anoctamin 1
- Aminopyridinol derivatives inhibit serotonin- and MDA-MB-231 human breast cancer-induced angiogenesis
- In-silico search for putative drug candidates against melioidosis based on the crystal structure of sedoheptulose-7-phosphate isomerase
- Idebenone, an ANO1/CaCC inhibitor found by High-throughput screening, has potential for use in cancer therapy
- Directions in convergent and creative pharmacy human resource development in terms of academia - focused on neuropharmacology
- Eco-friendly synthesis and catalytic activity of catechin-capped gold nanoparticles
- Oxidative Allylation of Aromatic and α,β-Unsaturated Carboxamides with Allylic Carbonates under Ruthenium Catalysis
- Inhibitors of Transcription Factor NF-κB: Structure-Activity Relationship studies on the Benzimidazole analogs
- The change of ginsenoside composition in the Red ginseng by the ultrasonication process
- A novel series of 3,5-disubstituted indole derivatives and their Pim kinase inhibitory activity
- Decarboxylative Acylation of Indolines with α-Keto Acids under Palladium Catalysis
- Design and synthesis of heat shock protein 90 inhibitors to impair the growth of non-small cell lung cancer (NSCLC)
- Instrumental analysis and quantification of beta-lactam antibiotic resistance in veterinary bacterial isolates
- Reversal of breast cancer using an innovating nano-vehicle based on biocompatible polymers
- Simultaneous profiling analysis of aliphatic, hydroxy and methyl-branched fatty acids by gas chromatography-mass spectrometry
- Quantitative analysis of trans-Anethole in Fennel seed by GC/MS
- Graphene oxide functionalized with poly(2-dimethylaminoethyl methacrylate) for efficient siRNA cellular delivery
- Highly sensitive electromembrane extraction for the determination of volatile organic compound metabolites in dried urine spot
- HPLC-UV analysis of the ortho-phthaldehyde in disinfectant for quality control
- Lipid-Enveloped ‘Smart’ Polyelectrolyte Complex Nanoparticles for Highly Effective Combination Chemotherapy
- Anisotropic biodegradable nanoparticles with enhanced capacity of surface ligand conjugation
- Dysfunctioned Tau by direct interaction with SOD1 G93A disrupts microtubule structure in axon
- Overview of polmacoxib (AcelexⓇ): Newly approved drug for osteoarthritis
- Evaluation of antioxidants in protein formulation against oxidative degradation using various biophysical analysis methods
- Reprogramming of human fibroblasts to neuronal precursor cells with plant stem cell-derived Molecule
- Effect of sarpogrelate on high-fat diet-induced nephropathy
- Melatonin effectively enhances aging indices by activating helper T cell signaling
- Mode Of Inhibition Of AXL Tyrosine Receptor Kinase by a heteroaryl Substituted Triazole Compound
- Roles of community pharmacists for pharmaceutical safety management
- Efficient DNA vaccination using chemoattractant loaded microsphere/polyplex releasing multi-layered microneedle
- Understanding of visible particulates and foreign insoluble matter test in biopharmaceutical product for international regulatory harmonization
- The critical role of negative feedback regulators in inflammation and host defense
- Development of Hot-Melt Extruded formulations with pressurized carbon dioxide
- A brief review on the establishment process of newly implemented 6-year pharmacy education program in Korea
- A rapid, sensitive and validated UPLC-MS/MS method for leuprolide analysis in rat plasma and its application to pharmacokinetic study
- Concise Synthetic Approach to Brazilin
- Effect of isoflavones on the lysosome and TFEB activity
- Connecting the present and the future, Hanmi’ s R&D strategy
- The March first independence movement of Chosun Pharmacy School students
- Discovery of active phytochemicals againts non-alcoholic fatty liver disease from Selaginella tamariscina based on dereplication using UPLC-DAD-QTOFMS
- Enhancement of Pharmacokinetic Profile and Antitumor Activity of Irinotecan using Polypeptide-based Block Ionomer Complex Micelles
- Inhaler Generic Development case - Fluterol Inhalation powder
- Identification and development of NamPT inhibitors as a synthetic lethal agent for NAPRT1-deficient lung cancers
- Inhibitory effects of Palmultang on inflammatory mediator production related to suppression of NF-kappaB and MAPK pathways and induction of HO-1 expression in macrophages
- A Novel compound from Antartic lichen restores cognition via suppression of inflammasome and BACE1 expression in Alzheimer’s disease mice
- Compound-14 isolated from Acanthopanax Root Bark inhibits inflammation by modulate the expressions of inflammatory marker via inactivation of MAPK pathway in murine macrophages
- Therapeutic effects of silibinin on the MPTP-induced Parkinson's disease model
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- Comparative study between different kinds of membrane for in vitro permeation test with Franz' diffusion cells using minoxidil topical solution
- Inhibition of advanced glycation endproducts formation by Korean thistle, Cirsium maackii
- Zingerone, an active ingredient of ginger, prevents carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats
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