학술논문
First-in-man study investigating safety, tolerability, and pharmacokinetics of BST204 after single and multiple ascending doses and the effect of food in healthy male volunteers
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- MIN Jee Sun BAE Soo Hyeon PARK Jung Bae KIM Doyun JANG Min Jung KIM Sun Ok KIM Jeom Yong YOO Young Hyo BAE Soo Kyung
- 간행물 정보
- 『춘계총회 및 학술대회』(2015년), 285~285쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2015.04.24
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- Molecular modeling & synthesis of b-raf inhibitor
- Affirmative impact of herbal medicine for various respiratory symptoms
- Hyaluronic acid-decorated poly(lactic-co-glycolic acid) nanoparticles for delivery systems of docetaxel and tanespimycin
- PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice
- Identification and Characterization of Aroma Compounds in Cudrania tricuspidata (Carr.) Burea
- Bone resorptive activity of zinc ion-sustained releasing ZnO chips
- Enhanced biovailability and lymphatic delivery of paclitaxel-loaded lipid nanocapsules
- Synthesis, characterization and biological evaluation of oxadiazole derivatives bearing 5-phenyl-tetrazole as osteoclast differentiation inhibitors
- Toxicity assessment of elemol from Chamaecyparis obtusa essential oil
- Effect of a Herbal Preparation (HemoHIM) on the Maturation of Bone Marrow Derived Dendritic Cells
- Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome for steatohepatitis
- Globular Adiponectin Causes Tolerance to LPS-induced TNF-α expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of ROS/FoxO3A Axis
- PTP1B inhibitory constituents from the aerial parts of Tradescantia spathacea Sw
- Young persimmon ameliorates obesity in leptin-resistant (db/db) genetically obese mice and affects adipose gene expression implicated in lipid metabolism and adipogenesis
- Evaluation of gastric motility activity of the extracts and isolates from traditional medicinal herbs
- Synthesis and biological activity of tricyclic derivatives containing a phenyl ring
- Population pharmacogenetic pharmacokinetic modeling for flip-flop phenomenon of entericcoated mycophenolate sodium in kidney transplant recipients
- Metabolomic profiling of valproic acid-induced rat model of autism spectrum disorders using 1H NMR spectral analysis
- Coumarins from Angelica decursiva inhibit lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells
- (-)-Menthol and related compounds in peppermint as testosterone 5α-reductase inhibitors
- Secondary metabolites of the aerial parts of Eclipta prostrata
- Two new compounds from the grains of Echinochloa utilis (Barnyard Millet)
- Pomolic acid inhibits invasion of breast cancer cells through the suppression of CXC chemokine receptor type 4 expression
- Green gold nanoparticles synthesized using earthworm extracts and the reinforcing effect on anticoagulant activities of heparin
- Effect of snail extract extract on chondrotin sulfate administration on growth increment, blood IGF-1, IGFBP-3 concentration in growing and old rats
- Chemical constituents from the leaves of Dryopteris erythrosora
- Development of physiologically based pharmacokinetic model of benzyl butyl phthalate and its active metabolite mono benzyl phthalate in rats
- A study on cardioprotective activity of ginsenoside-Re in ischemic damage
- Protective effect of Rhei Rhizoma on reflux esophagitis in rats through suppressing oxidative stress and inflammation
- Picroside II extracted from Pseudolysimachion longifolium suppresses MUC5AC expression via downregulating p38/ERK MAPKs and modulating transcription factors in NCI-H292 human lung mucoepidermoid cells
- Glucocorticoid- and long-term stress-induced aberrant synaptic plasticity are mediated by activation of the glucocorticoid receptor
- Hyperphosphorylation of tau in hippocampus in dab-treated mice might be associated with cognitive impairment
- Hepatoprotective Effect of Limonium tetragonum Extract Following Acute Alcohol Intoxicity in Rats
- Ginkgetin inhibits the growth of DU-145 prostate cancer cells through inhibition of STAT3 activity
- Phenolic compounds from Salicornia herbacea
- Resveratrol-mediated green-synthesis of gold and silver nanoparticles and their in vitro antibacterial activity
- Promising anti-diabetic potential of capillin and capillinol isolated from Artemisia capillaris
- Antiapoptotic effect of ginsenoside Rb1 against homosysteine on endothelial progenitor cells
- Four New Bakuchiol Dimer Analogues from the Seeds of Psoralea corylifolia
- A polymeric colon-specific prodrug releasing 5-ASA and benzocaine ameliorates TNBS-induced rat colitis
- Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathway
- Synthesis of novel 4′ α -trifluoromethyl-2′ β -C-methyl-carbodine analogs as anti-hepatitis C virus agents
- Role of IL-32alpha as an anti-inflammatory cytokine in MOG-induced experimental autoimmune encephalomyelitis
- Antioxidant effect of Selenigella tamariscina methanol extract on impairments induced by scopolamine in rats
- In vitro simulation of food effect on dissolution of BCS class III drug: The correlation of in vitro dissolution and in vivo absorption
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
- Persicarin isolated from the Oenanthe javanica protects against diabetes-induced oxidative stress and inflammation in the liver of streptozotocin-induced type 1 diabetic mice
- De novo design of doubly-stapled helicalpeptides as antimicrobial agents
- Anoctamin1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia
- Effects of scolopendrasin I, a novel peptide on atopic dermatitis in NC/Nga mice model
- Inhibitory effect of a sesquiterpine from Schisandra chinensis on an ovalbumin-induced asthma model
- Potentiation of ΔF508- and G551D-CFTR-mediated Cl- current by novel hydroxy pyrazolines
- Aqueous extract of Phyllostachyos Caulis in Taenian stimulates longitudinal bone growth in adolescent rats
- A new flavonoid and renoprotective activity of constituents from Sphagnum palustre
- Structural mechanism of ergosterol regulation and antifungal resistance by fungal sterol transcription factor Upc2
- Genetic Inhibition of Tyrosine Hydroxylase Potentiates Methamphetamine-Induced Neurotoxicity
- Shear stress enhances Ca2+ spark occurrence in rat ventricular myocytes via the activation of NADPH oxidase
- Ilex paraguariensis increases capability to resist starvation stress in Drosophila
- Intramuscular administration of novel SLNs-loaded dual-reverse thermosensitive nanomicelle with sustained release and reduced toxicity
- Synthesis and biological activity of imide derivatives
- An LC–MS/MS method for the determination of imperatorin in human plasma
- Korean red ginseng inhibits myocardial toxicity by doxorubicin
- Molecular modeling & synthesis of 11β-hydroxysteroid dehydrogenase type 1 inhibitor
- Drug repositioning: from anti-malarial drug to anti-obesity drug
- Catalase protects high-fat diet-induced early liver injury
- Antitumor activity of myriocin, a sphingolipid biosynthesis inhibitor, and its mechanism in melanoma mice
- Exogenous 8-oxo-dG prevents high fat-induced liver injury through enhancing mitochondrial biogenesis
- Attenuation of dbcAMP-induced Bad phospholylation in PC12 cells
- The influence of a CYP2C9 inhibitor on the pharmacokinetics of Meloxicam
- Comparison on tooth stain prevention effect of SAPP-contained mouthwash and others
- The inhibitory effect of SMB-6 on Rotenone induced endoplasmic reticulum stress and cell death in SH-SY5Y cells
- Signal transduction underlying the inhibitory mechanism of Fluoxetine on Electrical field stimulation response in rat ileal smooth muscle
- IL-4 mediated suppression of tumor development via activation of STAT6 in melanoma model
- Activation of NOX2 induces invasive phenotype in colon cancer cells through overexpression of MMP-7
- Delayed treatment with fenofibrate protects against high-fat diet-induced kidney injury via the AMPK-autophagy axis
- Prognostic gene signatures in pediatric medulloblastoma
- A Aovel [3+3] Annulation Approach to Indolizines from the MBH Allyl Bromides
- Species difference elucidation of 11β-hydroxysteroid dehydrogenase 1 through ensemble and induced fit docking studies
- Effect of the Conformational Restrictor in Benzamidochromenone derivatives for the inhibition of Interleukin-5
- Identification of inhibition modality of novel inhibitors for pim kinases using a fluorescence polarization assasy
- AME is a Mammalian Target of Rapamycin kinase inhibitor on EGF-induced neoplastic cell transformation
- Concentrations of benzodiazepines, hypnotics and sedatives in urine or blood forensic specimens related drug-facilitated crimes(DFC) in Korea
- Liquid chromatographic determination of creatine, dicyandiamide and dihydrotriazine in dietary supplements
- Nitric oxide-releasing poly(lactic-co-glycolic acid)-polyethylenimine nanoparticles for prolonged nitric oxide release, antibacterial efficacy and in vivo wound healing activity
- Chemical stability of bis-retinamido methylpentane, a novel hybrid retinoid derivative, and its in vitro and clinical efficacy
- Nitric oxide-releasing chitosan films for enhanced antibacterial activity and in vivo wound healing efficacy
- Quantitation of Biflorin in rat plasma by liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies
- In vitro skin permeation of disodium phenyl dibenzimidazole tetrasulfonate using Franz diffusion cell method
- Tacrolimus-encapsulated porous poly(lactic-co-glycolic acid) microspheres for treating bleomycin-induced pulmonary fibrosis
- Synthesis of Antifungal Evaluation of 2H-[1,2,3]Triazolo[4,5-g]isoquinoline-4,9-diones
- Pathogenesis-related proteins (PRP) from a dropwort play a role in regulating toll-like receptor-dependent downstream signal pathway
- Improved pharmacokinetics and brain delivery of resveratrol from N-Trimethyl chitosan-g-palmitic acid surface modified solid lipid nanoparticles
- Potentiated toxicity of multiple exposure to phthalates
- Inhibition of iNOS and cytokine induction by specific oligopeptides in fermented soybean extract from Glycine max
- Development and Evaluation of New Immediate-Release Dosage Form for Complex Migraine
- Chemical evaluation of marine sponge extract
- Strengthening immunity against influenza H1N1 virus by Morusalba L. fruit
- Chemotherapeutic potential of Hsp90 and biological evaluation of a novel Hsp90 inhibitor
- Requirements to be considered in the LIMS optimization process
- EGFR inhibitors for lung cancer therapy
- The Patents of material, the beginning of a new opportunity
- Process control strategy in biopharmaceutical manufacturing
- New alkaloids from roots and rhizomes of Veratrum nigrum L.
- Dual characterization of electroosmotic volume flow through skin and the modulation of ketoprofen flux using polyethyleneimine
- Dose-independent ADME properties and tentative identification of metabolites of a-mangostin from Garcinia mangostana in mice by automated microsampling and UPLC-MS/MS method
- Discovery of microRNA as a potential biomarker for colorectal cancer metastasis
- Visible light-induced perfluoroalkylations
- Steroid sulfatase induces epithelial mesenchymal transition (EMT) through HIF1a induction in human prostate cancer cells
- Dapoxetine decreased the excitability of small dorsal root ganglion neurons
- Optimization of oligonucleotide synthesis using DOE Study
- Oxazolone as a useful synthetic tool for amidation of aminoisobutyric acid
- Facile and simple functionalization of gold and silver nanoparticles with ampicillin
- Flavonoid constituents from n-butanol fraction of the aerial parts of Agrimonia pilosa Ladeb
- Interspecies pharmacokinetic scaling of FL-05 based on animal data
- Connecting the present and the future, Hanmi's R&D strategy
- Efficient siRNA delivery system using dendritic gold nanoparticle
- Design and synthesis of 1,2,3,4-Tetrahydroquinoline-2-carboxylic acid N-(substituted) phenylamide derivatives as potential NF-kB inhibitor
- Studies on the mehanism of inhibition of serum and glucocorticoid-inducible kinases (SGKs) by a pyrrolopyridine derivative
- Injectable biomaterials for the treatment of vocal fold disease
- The role of tauroursodeoxycholic acid on stem cells for bone tissue regeneration
- Methionyl-tRNA synthetase (MRS) controls CDK4 stabiltiy in p16INK4a negative cancer
- Understanding and utilization plan of the product approval and patent linkage system – in the product patent viewpoint
- Alzheimer disease and treatment
- Pharm-retail on healthmarket, O2O methodology with Retail 3.0
- Advancement of pharmacy management and case
- Stability of glutamate carboxypeptidase II, a glutamate synthesizing enzyme, is regulated by acetylation
- Promotion criteria for clinical faculty in US pharmacy schools
- Biological effects of phenolic compounds isloated from marine algae
- State-of-the art characterization of biopharmaceuticals for QC/QA using advanced mass spectrometry
- Analysis of the mission and goal of pharmacy education
- Pharmaceutical care service, a crucial sector in national healthcare system
- The Impact of Pharmacist-Initiated Interventions ImprovingAcute Coronary Syndrome Secondary Prevention
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- MFDS biopharmaceutical quality and pharmacovigilance policies
- Bidirectional actions of hippocampal Zn2+ signaling in cognition: its involvement in amyloid-β-induced cognitive decline
- Glutathione peroxidase 1 deficiency attenuates Concanavalin A-induced hepatic injury by modulation of T-cell activation
- Development of laboratory monitoring alert system of hyperkalemia related to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
- Modified delivery of axitinib that are nanohybrid liposomal nanoparticles effects on hypoxic tumor growth
- Resveratrol-mediated green-synthesis of gold and silver nanoparticles and their in vitro antibacterial activity
- Chromatographic enantiomer separation and determination of chemical and optical purity of α-amino acids and methyl esters as fluorenylmethoxycarbonyl derivatives with fluorescence detection
- Pharmacokinetic study in disease animal model
- A pharmacokinetics study of drug-drug interaction between 5-fluorouracil, irinotecan and BST204, a purified ginseng dry extract, after interavenous and intraperitoneal injection administration to rats
- Effects of scutellarein, a flavonoid of Scutellaria lateriflora, on inflammatory responses
- Involvement of mTOR signaling pathways in the neuroprotective effect of Eleutherin against the glutamate-induced hippocampal cell damage, mimicking severe Alzheimer’s disease brain condition
- siRNA-ligand conjugate system for targeted delivery
- Effect of 18:1 lysophosphatidylethanolamine on intracellular Ca2+ concentration through GPCR in neuronal cells
- Duel function of a novel compound E on platelet-derived growth factor-induced vascular smooth muscle cells
- Prenatal toll-like receptor-2 activation induces social and cognitive problems in female mice
- Enrichment of cells with high-level protein expression by destabilization of selection marker
- Protective effect of 8-oxo-2'-deoxyguanosine in high fat-fed mice kidney
- Chrysin enhanced the therapeutic efficacy of docetaxel in non-small cell lung cancer
- Preclinical assessment of toxicity and toxicokinetics of piroxicam after intra-articular injection in normal rats
- Genetic mechanisms for association between tobacco smoking and allergy
- Rdiation induced cancer risk assessment via dietary exposure
- Inhibitory effect of Hinokitiol on adipogenesis in 3T3-L1 preadipocytes
- Kaaempferol suppresses collagen-induced platelet activation through inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation
- Flexibility of β-arms of HU from Staphylococcus arueus dictates the DNA binding and recognition mechanism
- Role of Adiponectin in the pathogenesis of Alzheimer’s disease
- The prolyl isomerase pin1 interacts with a 90kDa ribosomal protein S6 kinase 2 to enhance TPA-induced cell transformation
- Role of moesin in HMGB1-stimulated severe inflammatory responses
- Autophagic dysregulation by altered expression of novel autophagy regulators in Parkinson’s disease model
- The interaction between Notch-1 and HIF-1α promotes ischemic neuronal death
- YP754 inhibits adipocyte differentiation via downregulation of PPAR-gamma in adipocytes
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- A novel PPAR pan agonist MHY2013 improves insulin-resistance and dyslipidemia in db/db mice
- Anti-osteoclastogenic activity of p38 inhibitor doramapimod via inhibiting migration of pre-osteoclasts and NFATc1 activity
- Repositioning potential of PAK4 to osteoclastic bone resorption
- Eukaryotic translation initiation factor, eIF2S2, promotes cell growth and migration in human cervix carcinoma cells
- Methanol extracts of Xanthium Sibiricum roots inhibit the inflammatory responses via the inhibition of NF-κB and STAT3 activation in murine macrophages
- Phaseollin inhibits endotoxin-induced inflammation in murine macrophages
- Solanum tuberosum L. cv Hongyoung extract inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice
- Increase of CCR7-dependent dendritic cell migration to lymph node by glucans
- Animal models for preclinical efficacy evaluation of stem cell therapy
- Rosmarinic acid inhibition of HIF-prolyl hydroxylase is potentiated by lipophilic modification of the natural product
- Target identification of thienopyrimidine derivatives by a chemical biology approach
- Studies on Phytochemical Constituents from Nandina domestica
- Heat-processing of Corni Fructus enhances renoprotecive effect on cisplatin-induced acute kidney injury in mice
- Attenuant Effects of Hydroponic-cultured Ginseng leaf extract on inflammatory collagen-induced arthritis in Rats
- Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced beta-cell damage and the development of type 1 diabetes
- Metabolism of evogliptin in human hepatic preparation
- Determination of the free thiol-containing antitumor agent, mertansine, in rat plasma by LC-MS/MS and its application to pharmacokinetic study
- Multiresidue method for the quantitation of 20 pesticides in aquatic products
- Role of cytochrome P450 and UDP-glucuronosyltransferases in metabolic pathway of homoegonol in human liver microsomes
- Method Development of NBOMes in Oral Fluid by Solid Supported Liquid Extraction and Gas Chromatography Mass Spectrometry
- Formulation,characterization and physicochemical evaluation of Melissa officinalis L. leaves tablets
- Sustained release Melt Extruded formulations using Eudragit RSPO and RLPO and content uniformity by FT-IR chemical imaging
- Pharmacokinetic comparison of a microgranule formulation with a tablet formulation of Desmopressin in Healthy Korean Subjects: A randomized, open-label, single-dose, 2-period crossover study
- Continuous twin screw granulation and powder rheological characterization of dry granules containing levetiracetam
- Development and evaluation of orally disintegrating tablet by inclusion complex
- In vitro and in vivo characterization of novel anti-AMF human monoclonal antibody for cancer therapy
- Particle design and in vivo evaluation of Eudragit E nanoparticle containing dutasteride
- Preparation of taste-masked solid dispersion containing palonosetron hydrochloride and evaluation of taste-masking efficiency using E-tongue
- The degradation profile and pH stability of Tenofovir Disoproxil
- Application of physiologically based pharmacokinetic (PBPK) modeling in prediction of pediatric pharmacokinetics
- Population pharmacokinetic modeling of midazolam in healthy volunteers : evaluation for drug-drug interaction
- Application of Advanced Compartmental Absorption and Transit model for prediction of human pharmacokinetic(PK) profile uisng preclinical in-vitro and in-vivo studies
- Effects of regulatory nuclear receptor (CAR, HNF4α and PXR) genetic polymorphisms on stable warfarin doses in patients with mechanical cardiac valves
- Oxidative C7-Acylation of Indolines with Aldehydes or Alcohols under Palladium Catalysis
- Two new lignans from the Fruits of Schisandra chinesis(Turcz.)Baill
- The Improving effect of Cucumis melo on atopic dermatitis in vivo
- Eriobotryae Folium improved inflammatory response through an oxidative stress and advanced glycation endproduct-meidated pathway in the liver of type 2 diabetic db/db mice
- New cytotoxic sesquiterpenoids from siegesbeckia glabrescens
- Taming the chemical reactivity and selectivity : Known and unknown paths (and somewhere between)
- Effects of AGS to stress caused by climate change
- Protective effects of Phosphatidylcholine on Oxaliplatin-induced neuropathy in rats
- Evaluation of questions from Cybercondriacs related to drug information and suggestion of providing evidence-based answer
- In-vitro study of Novel Active Ingredient for Dentin Hypersensitivity Toothpaste
- PEGylation effect of poly(amidoamine) dendrimers on cytotoxicity in hippocampal neuronal cells
- Synthesis and Biological Evaluation of Chemical Probes Targeting Hypoxia-Inducible Factor (HIF)-1α/ Malate Dehydrogenase 2
- Effects of geniposide on hepatocytes undergoing epithelial-mesenchymal transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways
- Society’ s eyes looking at the pharmacist community and The need for talent of consilience type
- Metabolomic application for MS based flavonoid research
- Cellular regulation of polyphenols compounds in cancer
- A friendly health communicator with professional qualification
- Prospectives of the clinical pharmacy education
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- A large-scale synthesis of self-assembled DNA nanostructures by rolling circle amplification for delivery of siRNA conjugates
- Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl) phenol Isolated from Butanol Fraction of Cordyceps bassiana
- Para-methoxymethamphetamine (PMMA) induces neurotoxicity and memory impairments in mice
- Characterization of the auditory electrophysiological responses in rat with salicylate-induced tinnitus
- P47phox plays a critical role in the apoptosis and reactive microgliosis induced by methamphetamine
- IRAK4 as a therapeutic target of innate immunity-imbalanced acute liver injury by chlorogenic acid
- Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter via nuclear receptor ERRγ in SH-SY5Y cells
- Anti-inflammatory Activities of Gouania leptostachya Methanol Extract and its Constituent Resveratrol
- Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice
- CYP2D6 genetic polymorphism significantly affects pharmacokinetics of Tolterodine
- The stereoisomers of crizotinib differentially induce change in the morphology of cancer cells
- Development of reactive metabolite screening system using human liver microsomes and LC-MS/MS
- Radiation human exposure and cancer risk assessment in cosmetics
- Evaluation of chemosensitivity using patient-derived xenograft model
- Ginseng total saponins induces the cardioprotection against ischemia/reperfusion injury
- Induction of integrin signaling by steroid sulfatase metabolism in HeLa cells
- A ring-truncated deguelin analogue induces apoptosis and anti-angiogenesis in non-small cell lung carcinoma cells
- Effects of apigenin and synthetic flavones on senescence-associated secretory phenotype in bleomycin-induced senescence in BJ fibroblasts and in vivo aged rats
- Cristacarpin inhibits endotoxin-induced inflammation in murine macrophages
- Anti-inflammatory effects of Crataeva nurvala Buch. Ham. Are mediated via inactivation of ERK but not NF-κB
- Contribution of the CD24 polymorphism to autoimmune disease: A meta-analysis
- Apatinib in HSA-PEG inhibits VEGF-induced retinal vascular permeability
- Selective C–H Cyanation of Indolines and Indoles with Easily Accessible Cyano Source under Rhodium Catalysis
- Selective C–H Allylations of Indolines and Indoles with 4-Vinyl-1,3-Dioxolan-2-One under Rhodium Catalysis
- Chiral separation of evodiamine in the biological sample by HPLC
- Pharmacokinetics and therapeutic efficacy of piroxicam, a long acting non-steroidal anti-inflammatory drug, after intra-articular injection in osteoarthritis-induced rats
- Structure ensemble based virtual screening discovered new inhibitors of tyrosinase
- Preparation and evaluation of oral disintegrating film containing local anesthetic agent, Lidocaine
- Determination of drometrizole trisiloxane by LC-MS/MS and application to an in vitro dermal absorption study
- The Misuse or Abuse of Stimulant Medications for Attention-Deficit/Hyperactivity Disorder (ADHD) in Adolescents and Adults
- Acerogenin A, a natural compound isolated from Japanese folk medicine Acer nikoense Maxim, prevents oxidative stress-induced neuronal cell death through Nrf2-mediated heme oxygenase-1 expression
- The potent medicinal plants, species of Lycopodiopsida, as a therapeutic agent for non-alcoholic fatty liver disease
- 4-Isopropyl-2,6-bis(1-phenylethyl)aniline 1 originated from Cordyceps bassiana has anti-inflammatory activities in macrophages
- Development of standard criteria for the quality evaluation of The Gentianae Macrophyllae Radix by TLC and HPLC
- Influence of MRP2 C24T genetic variant on the pharmacokinetics of Valsartan
- Alleviation of ischemia and reperfusion-induced liver injury by SPA0355
- Increased neural stem cell proliferation by quercetin-3-O-glucuronide
- Preparation and physicochemical characterization of cocrystal comprising celecoxib and tramadol hydrochloride for improved intrinsic dissolution rate
- Stereoselective total synthesis of 1-deoxygalactonojirimycin and research on total synthesis of 1-deoxyidonojirimycin via chiral 1,3-Oxazine
- Repositioning of Prickly Pears grown in Jeju Island for treatment of perimenopausal symptoms
- Drug development targeting Pin1-catalyzed conformational changes in cancer and Alzheimer’s Disease
- Beneficial effects of Humulus japonicus extract on hyperlipidemia and fatty liver induced by high-fat diet obesity
- Anti-cancer effect of (E)-4-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol on colon cancer cell growth by activation of DRs and inhibition of STAT3/NF-κB pathways
- Genetic inhibition of ceruloplasmin potentiates neurotoxicity induced by kainate
- Mitochondrial alteration and AMPK activation in NRF2-silenced human cancer cells
- Distribution of CYP2C19*10 allele in a Korean population
- Neuroprotective effects of WSY against lipopolysaccharide-induced neuronal damage
- 15-deoxy-Δ12,14-prostaglandin J2-induced cell apoptosis through ROS-mediated mechanism in gastric cancer cells
- In vitro activity of (-)-deoxypergularinine against Mycobacterium tuberculosis strains
- Potent and selective inhibition of sarpogrelate and its active metabolite, M-1, on the Human UDP-glucuronoslytransferase 1A4 activity
- Hydroquinone suppresses expression of IFN- β via AKT regulation
- Citrus unshiu peel extract protects cultured rat cortical neurons from beta amyloid-induced neurotoxicity
- Neuroprotective effects of labm99 on ischemia/reperfusion injury through inhibiting ASK1-JNK-p38 signal pathway
- Cordyceps pruinosa Buthanol fraction exhibit anti-inflammatory effect by suppressing of NF-kB activation
- 5-Aminosalicylic acid activates AMPK: an implication in anti-colitic activity of the anti-inflammatory drug
- Sphingosine-1-phosphate induces c-reactive protein via C/EBPβ and potentiates breast cancer progression
- Studied on inducing hair restoration of synthetic Oleanolic acid derivatives
- The comparison of health behavior by taking antihypertensive drugs in community pharmacy care service
- Organic anion transporter 3-mediated transport of verproside
- A multi-class analytical method for screening and confirmation of veterinary drug residues in fishery products based on liquid chromatography coupled to tandem mass spectrometry
- Preparation of chitosan coated alginate-Bee Venom nanoparticles
- Facile and Inexpensive microfluidic array chips for the detection of DNA/RNA pathogens
- Quantitative analysis of sphingomyelin by high-performance liquid chromatography after enzymatic hydrolysis
- Anti-inflammatory effects of fisetin by inhibition of Src and syk kinase activity
- In vivo gastroprotective effect along with pharmacokinetics, tissue distribution and metabolism of isoliquiritigenin in mice
- Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25-35 neurotoxicity
- Inhibitory effects on gstric lesions of Genipin
- Nrf2 regulates AhR activity, which contributes to cell survival
- Trp250-hK2 is defective in intracellular trafficking and actives the unfolded protein
- Ameliorative effect of caffeic acid cyloheylamide on protein kinase IKK-β- dependent immune-mediated early sepsis and liver injury
- Wound healing effect of the butanol fraction from Hydnocarpi Semen crude extract in ulcer injury of mice
- Two acidic amino acids, E143 and E705, contributes to calcium-dependent gating of Anoctamin 1
- Aminopyridinol derivatives inhibit serotonin- and MDA-MB-231 human breast cancer-induced angiogenesis
- In-silico search for putative drug candidates against melioidosis based on the crystal structure of sedoheptulose-7-phosphate isomerase
- Idebenone, an ANO1/CaCC inhibitor found by High-throughput screening, has potential for use in cancer therapy
- Directions in convergent and creative pharmacy human resource development in terms of academia - focused on neuropharmacology
- Eco-friendly synthesis and catalytic activity of catechin-capped gold nanoparticles
- Oxidative Allylation of Aromatic and α,β-Unsaturated Carboxamides with Allylic Carbonates under Ruthenium Catalysis
- Inhibitors of Transcription Factor NF-κB: Structure-Activity Relationship studies on the Benzimidazole analogs
- The change of ginsenoside composition in the Red ginseng by the ultrasonication process
- A novel series of 3,5-disubstituted indole derivatives and their Pim kinase inhibitory activity
- Decarboxylative Acylation of Indolines with α-Keto Acids under Palladium Catalysis
- Design and synthesis of heat shock protein 90 inhibitors to impair the growth of non-small cell lung cancer (NSCLC)
- Instrumental analysis and quantification of beta-lactam antibiotic resistance in veterinary bacterial isolates
- Reversal of breast cancer using an innovating nano-vehicle based on biocompatible polymers
- Simultaneous profiling analysis of aliphatic, hydroxy and methyl-branched fatty acids by gas chromatography-mass spectrometry
- Quantitative analysis of trans-Anethole in Fennel seed by GC/MS
- Graphene oxide functionalized with poly(2-dimethylaminoethyl methacrylate) for efficient siRNA cellular delivery
- Highly sensitive electromembrane extraction for the determination of volatile organic compound metabolites in dried urine spot
- HPLC-UV analysis of the ortho-phthaldehyde in disinfectant for quality control
- Lipid-Enveloped ‘Smart’ Polyelectrolyte Complex Nanoparticles for Highly Effective Combination Chemotherapy
- Anisotropic biodegradable nanoparticles with enhanced capacity of surface ligand conjugation
- Dysfunctioned Tau by direct interaction with SOD1 G93A disrupts microtubule structure in axon
- Overview of polmacoxib (AcelexⓇ): Newly approved drug for osteoarthritis
- Evaluation of antioxidants in protein formulation against oxidative degradation using various biophysical analysis methods
- Reprogramming of human fibroblasts to neuronal precursor cells with plant stem cell-derived Molecule
- Effect of sarpogrelate on high-fat diet-induced nephropathy
- Melatonin effectively enhances aging indices by activating helper T cell signaling
- Mode Of Inhibition Of AXL Tyrosine Receptor Kinase by a heteroaryl Substituted Triazole Compound
- Roles of community pharmacists for pharmaceutical safety management
- Efficient DNA vaccination using chemoattractant loaded microsphere/polyplex releasing multi-layered microneedle
- Understanding of visible particulates and foreign insoluble matter test in biopharmaceutical product for international regulatory harmonization
- The critical role of negative feedback regulators in inflammation and host defense
- Development of Hot-Melt Extruded formulations with pressurized carbon dioxide
- A brief review on the establishment process of newly implemented 6-year pharmacy education program in Korea
- A rapid, sensitive and validated UPLC-MS/MS method for leuprolide analysis in rat plasma and its application to pharmacokinetic study
- Concise Synthetic Approach to Brazilin
- Effect of isoflavones on the lysosome and TFEB activity
- Connecting the present and the future, Hanmi’ s R&D strategy
- The March first independence movement of Chosun Pharmacy School students
- Discovery of active phytochemicals againts non-alcoholic fatty liver disease from Selaginella tamariscina based on dereplication using UPLC-DAD-QTOFMS
- Enhancement of Pharmacokinetic Profile and Antitumor Activity of Irinotecan using Polypeptide-based Block Ionomer Complex Micelles
- Inhaler Generic Development case - Fluterol Inhalation powder
- Identification and development of NamPT inhibitors as a synthetic lethal agent for NAPRT1-deficient lung cancers
- Inhibitory effects of Palmultang on inflammatory mediator production related to suppression of NF-kappaB and MAPK pathways and induction of HO-1 expression in macrophages
- A Novel compound from Antartic lichen restores cognition via suppression of inflammasome and BACE1 expression in Alzheimer’s disease mice
- Compound-14 isolated from Acanthopanax Root Bark inhibits inflammation by modulate the expressions of inflammatory marker via inactivation of MAPK pathway in murine macrophages
- Therapeutic effects of silibinin on the MPTP-induced Parkinson's disease model
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- Comparative study between different kinds of membrane for in vitro permeation test with Franz' diffusion cells using minoxidil topical solution
- Inhibition of advanced glycation endproducts formation by Korean thistle, Cirsium maackii
- Zingerone, an active ingredient of ginger, prevents carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats
- Chromatographic enantiomer separation and determination of chemical and optical purity of α-amino acids and methyl esters as fluorenylmethoxycarbonyl derivatives with fluorescence detection
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