학술논문
Preclinical Pharmacokinetics and Scale-up of Anthracycline Anti-cancer Derivatives Based on Animal Data
이용수 3
- 영문명
- 발행기관
- 대한약학회
- 저자명
- SHIN Dae-Hwan LEE So-Young CHO Byung-Suk CHOI Kyu-Seok LEE Hong-Sub RYU Jung-Su KIM Tae-Yong SONG Suk Gil LEE Chong Kil CHUNG Youn-Bok
- 간행물 정보
- 『춘계총회 및 학술대회』(2008년) vol.1A, 341~341쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2008.04.30
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- Ursodeoxycholic Acid Regulates NF-eB and STAT Pathway of T- and B Cell-lines
- Validation of Analytical Method for Determina-tion of Tilianin in Agastache rugosa by HPLC
- Involvement of Calpain and Cathepsin in the Cleavage of Collapsin Response Mediator Protein-2 and Its Implication in the Neuronal Cell Viability under Ischemic Condition
- Magnolol Isolated from Magnolia obovata Enhances Pentobarbital-induced Sleeping Behaviors
- Allylmethylsulfide Inhibits Activation of NF-kB Signaling Induced by X-ray Irradiation in C57/BL6 Mice Kidney
- Chalcones from A ngelica keikei and their IL(interleukin) - 6 Inhibitory Activity
- Comparative Studies on Anti-inflammatory Effect of Angelica dahurica Root and Fermented A. dahurica Root in Raw264.7 Cell
- Gastroprokinetic Effects of DA-0701 , a New Prokinetic Agent Form ulated with Pharbitis Semen and Corydalis Tiiber
- Discovery of New Antagonists of GSK3b-Axin2 Interaction
- Design, Syntheses and Biological Evaluation of Novel TRPVl Antagonists
- Inhibitory Ability of Thiacremonone on the Activated NF-kB Enhances Susceptibility of Colon Cancer Cells to Docetaxel
- The Anti-inflammatory Effect of Chrysophanol in Mouse Peritoneal Macrophages
- Activation of ERK 1/2 and PI3K-Akt Pathways by CCL2 in the Primary Cultured Rat Cortical Cells
- A Studies on the Instrumental Analysis of Antibiotic Drugs
- The Analysis of Volatile Components of Processed Ginseng
- JNKl-Mediated Phosphorylation of Smac/ DIABLO is Functionally Linked to its Mitochondrial Release during TNF-a-Induced Apoptosis.
- Comparative Effects of Hypochlorite and Hydrogen Peroxide on the Relaxation of Esophageal Smooth Muscle of a Cat
- Improved Synthetic Methods for Pyranose-Annulated Natural Products
- Chemical Constituents Isolated from Polygala japonica Leaves and Their Inhibitory Effect on Nitric Oxide Production in Vitro
- A Facile Methods for the Functionalization of Peri-Position of Heteroaromatics: Utility of Acetates as a Potential Catalyst for Aldol-type Reaction
- Lipid Metabolism and Liver Protection of Vaccinium uliginosum L. in Ethanol Fed Rats
- Acrylamide Induces Apoptosis In Neural Progenitor Cells And Impairs Hippocampal Neurogenesis
- Temperature-dependent Volume Transitions, Cytotoxicities, and Gene IVansfection Efficiencies of Pluronic Decorated-nanogels for in vitro Usages
- Evaluation of Total Oxyradical Scavenging Capacity of Platycodon grandiflorum
- Honokiol Isolated from Magnolia obovata Potentiates Pentobarbital-induced Sleeping Behaviors through GABAΑ Receptors Activation
- The Synthesis and Anticonvulsant Evaluation of 6-amino-1,4-oxazepane-3,5-dione Derivatives
- Postmortem Determination o f Ethylene Glycol and Gycolic Acid by Gas Romatography-M ass Spectrometry in Human Specimens of a Cute Poisoning
- Inhibitory Effects of Obovatol, a Biphenolic Component of Magnolia Obovata, on Rat Arterial Thrombosis and Platelet Aggregation
- Efficacy and Safety Study of PurinoITM
- The Essential Components of Fungal β-1,3-Glucan Dependent Toll Signaling Pathway in the Mealworm, Tenebrio molitor Larvae
- Analysis of Methamphetamine and Amphetamine in Oral Fluid of Twelve Drug Abusers Using Solid-Phase Extraction and GC-MS
- The EfTect of Tanshinone I on Memory Relating ERK Signaling Pathway
- Protective Effects of Paecilomyces tenuipes Against Carbon Tetrachloride-induced Toxicity in Primary Cultured Rat Hepatocytes
- A Cell Based Screening for Wnt/β-catenin Pathway Inhibitors in Non-small-lung Cancer Cell Lines
- Synthesis of Mansonone F 01 Analogues and their Anti-MRSA Activities
- Regulation of Dihydrosphingosine-l-phosphate Release in F9 Mutant Cells by Fumonisin B₁
- Enhancement of Platelet Activation and Thrombus Formation by Silver Nanoparticles
- Anti-inflammatory Activity of an Ethanol Extracts of Saururus chinensis in an Animal Asthmatic Model
- Effects of L-Tetrahydropalmatine on Conditioned Place Preference and Locomotor Sensitization Induced by Methamphetamine
- Microarray Profiling Reveals Calcium-binding Proteins S100A8 and S100A9 as Candidate Markers for Invasive Human Breast Epithelial Cells
- Capsaicin Inhibits EGF-induced Migration and MMP-9 Activity in Lung Cancer Cells through ERK-, JNK and AP-1-dependant Signaling Pathway
- The Supramolecular Assembly of the Tripartite Multidrug Efflux Pump of Gram-negative Bacteria
- Cadmium Induced Gene Expression Changes in Human Lung Fibroblasts
- Protection of MPTP Dopaminergic Toxicity by EGb 761, a Standard Extract of Ginkgo Biloba; Involvements of Anti-inflammatory Action, Inhibition of PAF-Receptor, and Induction of PAF Acetylhydrolase
- Neuroprotective Effects of Sulforaphane Against a- Amyloid-Induced Cell Death and Memory Impairments
- Role of Protein Kinase C-5 as a Regulator of Hypoxia-Induced Angiogenesis
- Analytical Method of Oxidation Dye Components in Hair Dyes
- In vivo Pharm acological Characteristics of a Novel PPARg Modulator, PAM-1616
- The Effect of KH-red Ginseng Mixture Supplementation upon the Immune Response of Mice
- Synthesis and Cytotoxicity and Topoisomerases Inhibition of New Xanthone Analogues
- Inhibition of Diacylglycerol Acyltransferase by Phenylpyropenes Produced from Penicillium griseofulvum F1959
- Effect of Prenatal Administration of Polybrominated Diphenyl Ethers (PBDEs) on the Thyroid Hormone Levels and Neuronal Development in Juvenile and Adult Rats
- Comparison of Different IMAC Techniques for Quantitative Analysis of Sphingoid Base-l-Phosphates
- Polybrominated Diphenyi Ether (PBDE) and Thyroid Hormone Levels in Cord Blood of Infants in Korea
- Genexol-PM, a Polymeric Micellar Paclitaxel Formulation as Monotherapy or in Combination with Gemcitabine in Xenograft Model of Pancreatic ASPC-1 Carcinoma
- Activity Change of Sphingomyelin Catabolic Enzymes during Dimethylnitrosamine-induced Hepatic Fibrosis in Rats
- Compound K Inhibits Intracellular Triglyceride through AMPK Activation in HepG2 Cells
- Effects of Antioxidizing Activity, Anti-Platelet Aggregation Capacity and Stability of Anthocyanins from Blueberry, Cranberry and Red Cabbage.
- Quantitative Determination of Eleutheroside E from Preformulation Products of Acanthopanax Koreanum by HPLC
- Estimating Kidney Function in Children with Growth Retardation through Analysis of Vancomycin Pharmacokinetics
- Quantitative Analysis of Major Active Components from Astragali Radix by HPLC
- Mosquito Repellent Activity of DEET Analogues Determined by a New in vitro Assay
- Enhanced Bioavailability of Etoposide after Oral or Intravenous Administration of Etoposide with Kaempferol in Rats
- Quantitative Analysis of Major Active Components from Ostericum Radix by HPLC
- Effect of Astaxanthin on the Methamphetamine-Induced Neurotoxicity
- Pharmacokinetics and Tissue Distribution Profile of Doxorubicin Given Intratumorally Using Thermosensitive Hydrogel
- The Role of Peroxisome Proliferator Activated Receptor-α and Akt-Mediated 5'AMP-Activated Protein Kinases on the Fatty Liver induced by Orotic Acid
- Method Development for Quantitative Analysis of Isoorientin and Baicalin in UniflavonTM
- Effect of p-Glycoprotein on the Tissue Dstribution of DHP107, Oral Paclitaxel Formulation
- A Quassinoid 6α-Tigloyloxychaparrinone Inhibits Hypoxia-inducible Factor-1 Pathway by Inhibition of Eukaryotic Translation Initiation Factor 4E Phosphorylation
- The Effect of Heat TVeatment on the Phenolic Acid Contents and Antioxidant Activity of Inonotus Obliquus
- Effects of the Korean Pears, ly r u s pyrifolia cv. shingo, on Alcohol Detoxification in Aldh2-/- Mice
- The Effects of Litsea japonica on the Apoptosis Induction in the HL-60 and HL-60/ADR
- Effects of Flower and Stalk from Prunella vulgaris on the Macrophage Functions
- Neuroprotective Constituents of Dictamnus dasycarpus Root Bark
- Novel Piperazinylpropyipyrazole Derivatives as Dopamine D4 Receptor Antagonists with Therapeutic Potential for Schizophrenia
- Anti-obese Activity of Novel Cannabinoid- 1 Receptor Inverse Agonist GCC2680 in Mice
- Suppression of Inducible Nitric Oxide Synthase by Naphthoquinoids from the Bulbs of Eleutherine Americana
- Platelet Anti-aggregatory, Anti-coagulant and Vasorelaxation Effects of Compounds Isolated from Cinnamomi Ramulus.
- D/L-Configuration of Amino Acids in Peptides with Edman Degradation and Circular Dichroism
- Discovery Strategy of SKL11197 for Novel Neuropathic Pain Drug
- Food Consumption Increases the Systemic Exposure of Niflumic Acid Following Oral Administration of Talniflumate
- Patient Self INR Monitoring of Oral Anticoagulation
- The Effect of Dispensing Error Prevention Program on the Incidence of Dispensing Error in Hospital Pharmacy
- Development of an in vitro Test System Measuring Transcriptional Down-regulatory Activities on IL-13
- Anti-diabetic Activity of a Novel Cannabinoid- 1 Receptor Inverse Agonist GCC2680 in Mice
- Antiobesity, Antihyperlipidemic, Hypoglycemic Effect of the Black and Green Tea Supplementation on Hyperlipidemic-induced Diabetic Rats
- Comparative Study on the Regulations of Controlled Substances
- Guideline on Evaluation of Clinical Trials in Korea- Neuropsychological Drug
- Dose-dependent Pharmacokinetics, Hepatic and Gastrointestinal First-pass Effects, and Hepatic CYP Isozymes Responsible for Metabolism of Mirodenafil, a New Erectogenic, in Rats
- Cognitive-Enhancing Activity of Decursin Derivatives
- Evaluation of the Use of HMG -CoA Reductase Inhibitors for the Patients with Renal Insufficiency in a University Hospital
- Bergamottin Suppresses PMA-mediated Matrix Metalloproteinase-9 Activation through Down-regulating Nuclear Factor-kB
- Development and Optimization of a Novel Sustained-release Tablet Formulation for Bupropion Hydrochloride Using Box-Behnken Design
- Anti-Stress Effect of Korean Red Ginseng on Immobilization-Stressed Mice via PADI4, a Stress Marker
- Nucleolin : Another Role as a Receptor of Acharan Sulfate
- Prunus yedoensis Barks Inhibit the Inflammatory Chemokines (MDC & TARC ) in IFN-γ Stimulated HaCaT Keratinocytes
- Apoptosis-inducing Activity of 2 ,4,6-Trihydroxy-2-Geranylacetophen one in Adriamycin -Resistant MCF -7 Breast Cancer Cells
- Biochemical Characterization of the Smallest Class IV Adenylyl Cyclase from Yersinia pestis
- Antiproliferative Effect of Fisetin on Rat Aortic Vascular Smooth Cell by Gl-Cell Cycle Arrest
- Induction of Inflammation Signals by Silica Nanoparticle in Murine Macrophage Cell Line, RAW 264.7
- Antiproliferative Activity of JY0691, a Newly Synthesized Obovatol Derivative, on PDGF-BB-stimulated Rat Aortic Vascular Smooth Muscle Cells
- Surfactin from Bacillus subtilis Acts as a NF-kB Inhibitor in Inflammatory Conditions
- Molecular Control and Antibacterial Activity of Phenoloxidase-Induced Melanin Synthesis in Larvae of the Beetle, Tenebrio Molitor
- study on the Inhibitory Effect of GS Extract on Aβ Oligomer-induced H19-7 Cell Death Model and Drosophila Model of AD
- Sophoricoside Inhibits 2,4-Dinitrochlorobenzeneinduced Contact Dermatitis in Balb/c Mouse
- Shizukaol B Inhibits the Immune Functions of B Cells, but not T cells, Macrophages, and Dendritic Cells
- Effect of Ochnaflavone on Septic Arthritis Due to Candida albicans
- Evaluation of the Adjuvant Activity of CIA07 to Anthrax Protective Antigen
- Antifungal Effect of Glycyrol, a Component of Glycyrrhizae Radix, against Candida albicans
- Abnormalities in Regulation and Interaction of Lymphocytes in the Pristane-Induced Lupus Mice
- Akt Up-regulates Smac Activity by Phosphorylation during Etoposide-induced Apoptosis of HeLa Cells
- Bovine Lactoferrin Inhibits OVA-Specific Allergic Responses
- TP 53 Restoration Using Combined Cisplatin and E6/E7 siRNA Leads to l\im or Regression in Cervical Squamous Cell Carcinoma
- The Crosstalk between Wnt2 and ERK Pathway in Non-small-cell Lung Cancer Cell Lines
- Hyperoside Prevents Oxidative Damage Induced by Hydrogen Peroxide in Lung Fibroblast Cells via an Antioxidant Effect
- Xylocydine Induces Apoptotic Cell Death of Hepatoma Cells by Inhibiting CDK
- Rapamycin, mTOR Inhibitor, a Potent Cell Growth and Proliferation Inhibitor by p21-Dependent Mitotic Arrest in Human Gastric Cancers
- Cloning and Functional Analysis of 5'-flanking Region of Metastasis-Associated 1 Gene
- Triterpenoids from Leaf of Diospyros kaki and their Inhibitory Effect on Protein Tyrosine Phosphatase IB
- Isolation and Antioxidant Ability of Phenolic Compounds from Geranium nepalense var thunbergii
- The Sulindac Derivatives Bind α₁-antitrypsin
- Inhibitory Effects of Chromatographically Fractionated Extracts from Chrysanthemum zawadskii on Tyrosinase Activity and Melanogenesis
- Protective EfTect of Butanol Fraction of Phaleria macrocarpa On Oxidative Stress Associated with Streptozotocin Induced Diabetic Mice
- Action Mechanism of HTIO in Biophysical Perspectives: HTIO Binds to VEGF Strongly and Causes Severe Structural Changes
- Oxaliplatin-induced Peripheral Neuropathy in Patients with Advanced or Metastatic Gastric Cancer
- Pharmacokinetic Interaction between Telithromycin and Metformin in Rat Model of Diabetes Mellitus Induced by Streptozotocin
- Comparative Study on the Regulations of Biological Medicinal Products
- Gai-Mediated LDL-Induced Aortic Smooth Muscle Cell Proliferation
- Salsolinol, an Endogenous Neurotoxin, Enhances Platelet Aggregation and Thrombus Formation
- Cellular Mechanism of the QT-Prolongation Induced by Sulpiride
- Propenone Derivatives Inhibit Vascular Endothelial Growth Factor-induced Agiogenesis in vitro and in vivo
- Apoptosis Inducing by Sesquiterpenes Isolated from Magnoliae obovata
- Co-delivery of Curcumin and Daunorubicin via Liposomes for Synergistic Anticancer Effects
- Identification o f hFAFl Binding Proteins; NPL4 and UFDl are Interacting with hFAFl via VCP
- Strategy for the New Drug Development in Korea
- Rapid and Sensitive Determination of Losartan in Human Plasma by LC-ESI/MS/MS
- Formulation of Cationic Liposome Gel for Amphotericin B
- Effects of Hwang-ryun-hae-dok-tang on the Pharmacokinetics of Phenolsulfonphthalein, a Model Organic Anion Drug
- Renovation of Pharmacy Education in Japan - A Key Role of On-site Pharmacy Training
- Nicotine Attenuates Both iNOS and nNOS Involved Antioxidative Effects and Contributes to Neuroprotection in Spinal Cord Injury
- Immunological Adjuvant Effect of Cudrania tricuspidata on the Immune Responses to Ovalbumin in Mice
- Pre-pharm Courses for PEET and Admission Guideline in Korea
- Study of a Proposed Korean National Biological Standard of Human Anti-Hepatitis B Immunoglobulin for Potency Test
- Neuroprotective Effects of Licochalcone E from Glycyrrhiza Inflata Involves Anti-inflammatory and Anti-Oxidative Activity
- AKT Up-regulates the Interaction of Osterix with Osterix-Binding Partners and Transcriptional Activity
- Sirt2 Acetylation by Acetyltransferase p300 Attenuates Its Deacetylase Activity
- Functional and Structural Studies of Secretagogin,Novel Calcium Binding, Using Proteomic Analysis
- Protective Effects of Paeoniflorin Against LPSinduced Cytotoxicity and Genotoxicity in MTT and Comet Assays
- Effect of Horse Bone Extract on the Osteoporotic Factors in vitro and invivo
- Thl/Th2 Cytokine Modulation in Human PBMC by Acanthopanax divaricatus var. albeofructus
- The Quantitative Analysis of Rutin in Mori Folium by High-Performance Thin-layer Chromatography(HPTLC)
- Quantitative Analysis of Schizandrae Fructus Based on the Origin by HPLC
- The Effect of Herbal Extracts on Osteoclasts
- Down-regulation of the Organic Cation Transporters of Rat Liver and Kidney in Ethynylestradiolinduced Cholestasis
- PCRW Inhibits Catecholamine Secretion from the Isolated Rat Adrenal Medulla
- Effect of Morin, a New Flavonoid, on Liver Damage in Rats with Dimethylnitrosamine-induced Cirrhosis
- Development of an Anti-inflammatory Bio-therapeutic
- Inhibition of NF-kB by Ginsenoside Rg3 Enhances the Susceptibility of Prostate and Colon Cancer Cells to Docetaxel
- Exploring Marine Bacteria Associated with a Marine Ascidian in the East Sea and their Secondary Metabolites Production
- Phospholipase D from Streptomyces Tendae with Hydrolytic and IVansphosphatidylation Activity.
- Inhibition of Dual-Speciflcity Protein Phosphatases (DUSPs) by NSC-87877
- Synthesis, SAR and Evaluation of 4-Substituted Biaryl Pyrazoles as CBl Cannabinoid Receptor Antagonists
- Synthesis and Structural Activity Relationship of Benzoxathiol-4-one Analogues as Inhibitor of NF-kB Activation
- Synthesis and Hypnotic Activities of 7V-Cbz-αaminoglutarimidooxy Carboxylate Derivatives
- Synthesis of o-Carboranylphenols as Potential BNCT Agent
- Synthesis of Terpyridine Bioisosteres and Evaluation of their Antitumor and Anti-inflammatory Activity
- Novel Ligands of Peroxisome Proliferator-Activated Receptor Delta for IVeatraent of Obesity
- Novel HDAC Inhibitor, KBH-A145; Synthesis and Biological Evaluation
- Synthesis of 2-thienyl-4-furyI-6-aryl-pyridinederivatives and Evaluation of their Antitumor Activity
- Isolation of Compounds from Seeds of Plantago asiatica L.
- RCM Application for the Totoal Synthesis of Natural Protoberberine Alkaloids
- Synthesis of 2-Substituted-5,8-Dimethoxy-l,4-Naphthoquinone Analogues and Their Inhibition of ACAT
- Novel Anticancer Substance from The Insect-Flower, Cordyceps militaris
- Effect of Pectolinarin on the Production of Pro-Inflammatory Cytokines
- Isolation and Identification of Antioxidant Compounds from Agrimonia pilosa
- Improved Quality Control Method for Scrophularia spp. by HPLC-DAD and Discriminant Analysis for Classification
- The Chemical Constituents of the Stems and Leaves of Rhus sylvestris
- Phytochemical Constituents from Flowers of Clerodendron Trichotoinum
- Antioxidant and Antiinflammatory Components Isolated from M outan Radicus Cortex
- Novel Dimeric ent-Kauranoids from Isodon excisus
- Study on Antioxidant Constituents of Vietnam Bitter Tea Ilex kudingcha
- Oligostilbenes from the Root of Caragana sinica
- Ginsenoside Rb2 Inhibits Gluconeogenesis in HepG2 CeUs via AMPK Phosphorylation
- Anti-Oxidative and Nitric Oxide Production Inhibitory Effect of Wood Vineger from Korean Red Pine(WVK)
- Hyperlipidemic Inhibitory Activity of Chungkookjang
- Hepatoprotective Effect of Acteoside-1 isolated from Acer termentosum Max on D-galactosamine induced Liver Injured Rats
- Inhibitory Constituents of Aldose Reductase from Glycyrrhizae Radix
- Capillary Electrophoretic Separation of PEGylated Granulocyte-colony Stimulating Factor
- Simultaneous Analysis and Quantification by High Pressure Liquid Chromatography of Preservatives in Commercial Pharmaceuticals
- Proteomic Strategies for Identifying Sumoylated Proteins and Sumoylated Sites.
- Metabolic Profiling Analysis of Fatty Acids in Lipids and Free Fatty Acids as tert-Butyldimethylsilyl Derivatives by Gas Chromatography
- Phorbasins D-F: Three New Diterpenoids from the Marine Sponge Phorbas sp.
- The Anti-oxidative Activities and Separation of Extracts from Galla Rhois
- Removal of Herbicides Using Surface Engineered Carbon
- Combining Several Experimental Data from Coffee as an Effective Discrimination Tool in Metabolomics
- Tanshinone II A Induces S Phase Cell-cycle Arrest and Apoptosis in Activation of R at Hepatic Stellate Cells in vitro
- Stability Study of Megestrol Acetate Oral Suspension by Dispersion Optical Analyser
- Development of Valsartan-loaded Solid Dispersion with Spray Drying Method Using Gelatin and HPMC2910
- Effect of PEGylated Liposomal Cromolyn in Pancreatic Cancer
- Enhanced Solubility and Dissolution of Sibutramine Using Solid Dispersion Prepared with HPMC2910, Poloxamer 407 and Citric Acid
- Electrotransport o f levodopa: Electrorepusion vs Electroosmosis
- Characterization of Sustained Release Tablets Containing Solid Dispersion Granules
- Plasma Pharmacokinetics o f 2'-Benzoyloxycinnamaledhyde, an A ntitum or Drug Candidate, in Rats
- Studies on the Physicochemical Characteriazaiton of Dexibuprofen Loaded Organic Gel Formulation.
- Prevention and Therapeutic Effects of Hydrolyzed Products of Aloe vera for Atopic Dermatitis of NC/Nga mice induced D. pteronyssinus
- Topical Formulation of Pine Bark Extract (Pinexol？？)
- Small Interfering RNA Transfection Using New Cationic Lipid-based Liposomes
- TVansport and Metabolism of JAC106, an NO Donor-containing Tubulin Binding Agent, in Caco-2 Cells
- Effect of M DRl Genetic Polymorphisms and Intrasubject Variabilities on the Pharmacokinetics of Levosulpiride in Multi-occasion Studies
- Bioequivaience Evaluation of Cefprozil 250 mg Tablets in Healthy Male Korean Volunteers
- Dose-independent Pharmacokinetics of Liquiritigenin after Intravenous and Oral Administration to Rats: Contribution o f Hepatic and Gastric First-pass Effect to Low Bioavailability in Rats
- Sensitive Determination of Amoxicillin in Human Plasm a by Liquid Chromatography-Tamdem Mass Spectrometry
- DA-9701, a Herb-based Prokinetic Agent, Provokes Pacemaker Currents in Interstitial Cells of Cajal from Murine Small Intestine
- Inhibitory Effect of Salidroside and Tyrosol from Rhodiola Sachalinensis on Meianogenesis
- Deformable Liposomes for Percutaneous Delivery of Conjugated Linoleic acids
- Arraypedia: A New Integrated Database of Microarray for Virtual Validation of Anti-cancer Target Candidates
- Plasma Pharmacokinetics and Tissue Distribution of Genexol？？-PM in Xenografted H460 Nude Mice
- Activation of the Genomic Estrogen Receptor Pathway by Water Extracts of Cirsium Japonicum
- Protection Against Ethanol-Induced Liver Injury and Impaired Metabolomics of Sulfur-Containing Substances by Betaine Supplementation
- U-shaped Dose Response in Vasomotor Tone: A Mixed Result of Heterogenic Response of Multiple Cells to Xenobiotics
- Pharmacological IVeatment of PPARdelta Agonist Promotes Physical Endurance
- Toxicoproteomics: Identification of Biomarkers by Serum Glycoproteom Analysis in Mercury TVeated Mouse Using Nano UPLC Q-TOF Mass Spectrometry
- Inhibitory Effect on Replication of Enterovirus 71 of Herb Methanol Extract
- Superior Dopaminergic Neuroprotective Effect of Phenidone, a Dual Inhibitor of Cyclooxygenase and Lipoxygenase
- The Effects of Isoquinoline Compounds against APP Metabolism
- Overexpression of Program Death-1 Gene in T cells Prevents Streptozotocin-induced Type 1 Diabetes
- Effect of Cinnamaldehyde on Macrophagemediated Inflammatory Responses
- hARD l235 Supports Cellular Growth through AP-1 Transactivation
- Bioactive Flavonoids on Alcohol Metabolizing Enzymes from Echinosophora koreensis
- Hypoxia Induces Epithelial Cell Proliferation by Downregulation of a T\jmor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal motifs (RECK) through
- Screening and Development of Peroxiredoxin Inhibitors as Anticancer Agents
- Discoidin Domain Receptor 1 Mediates Oxidative Stress-induced Cell Death
- Novel Chalcone JSH 04-4 Inhibits Nuclear FactorkB Activation and Inflammatory Mediator Production in LPS-Activated Macrophages
- High-level Expression and Purification of the Chemokines Fused with Maltose Binding Protein in Escherichiacoli (E, coli)
- In vitro Pharmacological Characteristics of a Novel PPARy Modulator, PAM-1616
- Reduced Anxiety in the Transgenic Mice Expressing Presenilin 2 Mutation
- Study of Novel Mechanism of Tumor Suppressor Gene, SMAD4 in Gastric Carcinoma
- Therapeutic Anti-VCAM-1 Antibody Development
- The Supramolecular Assembly of the Tripartite Multidrug Efflux Pump of Gram-negative Bacteria
- Topical Formulation of a Newly Synthesized Molecule Based on the Preformulation
- Introduction: Overview of Physiology of Oxidative Stress and GPCR-G Protein Signaling
- Phagocytic Removal of Apoptotic Cells in Drosophila: Identification of a Receptor and a Ligand
- Gene Expression and Functional Characterization of a Novel Cation Transporter PMAT in the Rat Blood-Brain Barrier
- The Potential Anti-Gastric Diseases Activities of Gardenia jasminoides Ellis and its Constituents
- Total Synthesis of Glycyrol
- structure Activity Relationship of Anti-Inflammatory 2',4',6'-Tris(mettioxymetfioxy)chalcone Derivatives
- Novel Synthesis of Methylene Bridged Isomeric Nucleoside Analogues with Flexible Conformations
- Antibacterial Butenolides from a Korean Marine Tunicate
- Isolation and Identification of Components from Polygonati odorati Rhizoma
- IViterpenoids Isolated from the Roots of Aucuba japonica and their IL (interleukin) - 6 Inhibitory Activity
- Minor Constituents from Anemarrhena asphodeloides
- Constituents from the Flowers of Lonicera Japonica
- Two New Lupane Glycosides from the Leaves of Acanthopanax Koreanum
- Chemical Constituents from Acer tegmentosum
- Cytotoxicity Activity Constituents from Aceriphyllum rossii
- Anticancer Activity on NCI-N87 Cells of Buthanol Fraction from Picrasma Quassioides (D. Don) Benn.Methanolic Extract
- Guideline for Non-clinical Efficacy Tests of Antihyperlipidemic Herbal Medicinal Products
- Chromatographic Enantiomer Separation of N -Benzyloxycarbonyl Amino Acids and Their Ester Derivatives on Covalently Immobilized and Coated Chiral Stationary Phases Based on Polysaccharide Derivatives
- Measurement of Dopam ine, Their Metabolites and Serotonin by High Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate
- Application of NIR to Quality Control of Plant Extracts
- Enantiomer Resolution and Its Application Using a New Covalently Bonded Chiral Stationary Phase Derived from Cellulose Tris(3,5-chlorophenyIcarbamate) in HPLC
- Development of an Analytical Method for the Determination of Residual Nitrovin in Livestock Products using HPLC/UV
- Development of a Novel Sustained-release Tablet Containing Doxazosin Mesylate
- Development of Self-micro Emulsifying Drug Delivery Systems (SMEDDS) o f Coenzyme Q10 for Functional Food
- Effect of Microneedle on the Pharmacokinetics of Ketoprofen from Its Transdermal Formulations
- Erythrocyte Ghosts for Delivery of Antisense Oligonucleotides
- HPLC Method for the Analysis of Doxorubicin in Mouse Plasma and Tissues with Minimal Sample Size Requirement
- Controlled Release of Cyclosporin A Using Nanostructured Lipid Carriers
- Preparation and Characterization of Polyvinyl alcohol/Chitosan Gel-matrix Based Wound Dressing Systems Containing Minocycline Hydrochloride
- Pharmacokinetic Parameters of Oltipraz in Liver Cirrhotic Rats with Diabetic Mellitus
- Influence of Quercetin on the Pharmacokinetics of Phenolsulfonphthalein in Rats
- Proteomic Analysis of Human Peritoneal Mesothelial Cells Treated with TGF-βl
- NF-kB Activation is Involved in Tetrahydrobiopterin-induced Dopaminergic Cell Death
- Purification and Organic Synthesis of a Novel Neuroprotective Compound (SP-8203) from the Earthworm,Eisenia andrei
- Anticancer Effect of Mcl-l siRNA Against Hepatoma Cells
- Hepatic Toxicity of Perfluorooctanoic Acid in Mice
- Establishment of a GFP-HIF l a Stable Cell Line for Assessment of Carcinogenicity of Chemical Toxins
- Potentiation of Ethanol-Induced Liver Injury and Impairment of Sulfur-Containing Substance Metabolomics in Gpx-1 /Cat Mice
- The Effects of the Seed of Cassia Obtusifoiia on Cerebral Global Ischemia in Mice
- Development of an Assay System for the Screening Anti-Allergy Drugs Through Cytokines of Rat Basophilic Leukemia (RBL)-2H3 Mast cell On Ab-Ag Stimulation.
- Modulation of Age-related Vascular Inflammation by Calorie Restriction and Betaine Treatment
- Identification and Functional Analysis of Meteorin in Zebrafish CNS Development
- α-Tocopheryl Succinate Inhibits Prostaglandin E2 Production and Cyclooxygenase Activity in Macrophage cells
- Regulation of Platelet Aggregation by a Reactive Oxygen Species (ROS)-mediated Signaling Network
- Sulfiredoxin Translocates to Mitochondria and Regulates Reduction of Sulfinic Peroxiredoxin III under Oxidative Stress
- Composition of Proteins Located at Plasma Membrane and Exosome from Kidney Tissue
- Collection of New Marine Microorganisms and Useful Natural Products from Marine-derived Microorganisms
- Anxiolytic-like Effects of Portulaca Oleracea Linne Using the Elevated Plus-maze Test in Mice.
- Development of Image-based Calcium Mobilization Assay in Single Cells Based on High Content Screening Technology
- Antioxidant Potential and Quantitative Analysis by Using LC/MS/MS with Rosmarinic Acid for Perilla Frutescens Extracts
- Bioactive Compounds Isolated from Stem Bark of a Vietnamese Medicinal Plant Gardnia oblongifolia(Clusiaceae)
- Influence of the Delivery Systems Using a Microneedle Array on the Permeation of a Hydrophilic Molecule, Calcein
- Isolation, Structure Elucidation, Antioxidant Evaluation with On-line HPLC-DPPH Method of Radical-Scavenging Hispidin Derivatives from Fruiting Body of Phellinus linteus
- Suppression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Expression by l\issilagone from Farfarae Flos in BV-2 Microglial Cells
- Neuroprotective Effects of SP-8203 in Ischemic Brain Injury
- Hederacolchiside Al-induced Apoptosis in Immortalized Keratinocytes
- Polymeric Nanoparticles with Anticancer and Contrast Imaging for Liver Cancer
- Redox Signaling of G Protein-coupled Receptors
- Regulation of Innate Immunity for Host-Bacteria Symbiosis
- Citrus Grandis Osbeck Leaves Inhibit the Production of NO and IL- 6 by Down Regulationg JNK Activity in LPS-Stimulated RAW 264.7 Cells.
- Actin Cytoskeleton is Responsible for Src Kinase Activation
- cDNA Cloning and Expression of Spatzle Processing Enzyme(SPE) Involved in Lysine-iype Peptidoglycan Recognition Signaling Pathway in Tenebrio Molitor Larvae
- Relationship between Epigenetic Modifications and Activity/Safety of Embryonic Stem cells
- Comparative Analysis of Proteome Profiles of Helicobacter pylori 26695 Cultured under Aerobic and Microaerobic Conditions
- Evaluation of in vitro Stability of Natural and Modified Enkephalins
- Pharmacokinetic Characteristics of Intranasal Levodopa and Carbidopa Form ulation in Rats
- In vitro Absorption and Metabolism Characteristics of 2'-Benzoyloxycinnamaldehyde, an Antitum or Drug Candidate
- Determination of MirodenaHi, and Its Metabolites, SK3541 and SK3544, in Rat Plasma, Urine, and Various Tissue Homogenates by High-performance Liquid Chromatography
- Purification and Physiological Function of a Lectin from Macrophthalmus japonicus
- Preparation and Evaluation of Novel Cationic Solid Lipid Nanoparticles for the Delivery of p53 gene into Lung Cancer Cells
- Effect of Rifampicin on the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone in Rats
- Validation of Analytical Procedures
- Drug Product Quality Assessment and Global Regulatory Harmonization
- Development of Novel A3 Adenosine Receptor Antagonists
- Modulation of P-Glycoprotein-mediated Transport by Naturally Occurring Compounds
- Role of Transporters on Pathophysiological Aspect of the Blood-Placenta Barrier
- Gastroprotective Effect of QGC on Indomethacin-lnduced Gastritis in Rats
- Anti-inflammatory Activity of (Z )-Ligustilide and Senkyunolide A via Inhibition of NF -kB Pathway
- Manassantin A Inhibits Maturation and Immune Functions of Bone Marrow-Derived Dendritic Cells
- Transient Global Ischemia Induces Morphological Changes in the Hippocampal CAl Region and Memory Impairments in Mice
- Regulation of Soluble Amyloid Precursor Protein Alpha and Cell Viability by Amyloid Beta in SH-SY5Y Cells
- Correlations between Quantitative EEG Cordance Evoked by Music Listening and Personality Traits
- Prevention of P-cell Destruction and Inhibitory Roles of Laccase in the Process of p-cell Damage by Its Radical Scavenging Property
- GCC1290, a New Oral Drug Candidate for the Treatment of Parkinson's disease
- Cytotoxic and Anticomplementary Components from Herbal Medicines
- Orphan Nuclear Receptor Nur77 Is Acetylated by p300
- Ursodeoxycholic Acid Decreases Expression of Inflammatory Factors and Co-stimulatory Molecules via Inhibition of NF-kB and STAT I Pathway in RAW264.7 Macrophages
- Characterization of Viable but Nonculturable Condition of Escherichia coli Induced with Copper
- Induction of Differentiation of Human Promyelocytic Leukemia HL-60 Cells by Nargenicin
- Anti-Colon Cancer Effects of Fucoidan Isolated from Fucus vesiculosus
- The Role of LXR in the HBx-induced Hepatic Lipogenesis
- Design and Synthesis of Guanidine Derivatives toward Development of iNOS Inhibitors
- Growth Inhibition and Induction of Autophagy by Yuanhuadine in Human Lung Cancer Cells
- 1624 G>C single Nucleotide Polymorphism in 3'-untranslated Region Influences the Expression of SUV39H2 Histone Methyltransferase
- Enhancement of the Anti-Proliferative Effects on Human Colon Cancer Cell Lines by Bifidobacterium adolescentis SPM0212 Extract
- Synthesis and Anti-inflammatory activity of [I-3',II-7]biflavone Analogs
- Purification of Snail-importin β Protein Complex
- Rapid and Sensitive Determination of Acyclovir in Hum an Plasma by HPLC/UV
- Synthesis and Biological Evaluation of Pregnane Derivatives as 5α-Reductase Inhibitor
- Determination of an Agent for the Inflammatory Liver Disease, Liquiritigenin, in Rat Plasma, Urine, and Various Tissue Homogenates by High-performance Liquid Chromatography
- Cytotoxic Components of Picrasma Quassioides
- Analysis on Perception of Price Managers in Pharmaceutical Companies on Positive List System in Korea
- Anti-Stress Effect of Lactic Acid Bacteria in ICR Mice
- Antiproliferative Effect of Fermented Ginseng, BST-204, on HT-29 Human Colon Cancer Cell
- Comparative Changes in the Metabolomics of Sulfur-Containing Substances in Liver of Rats TVeated with L-Buthionine-(S,R)-Sulfoximine (BSO) and Phorone (PHO)
- Blockade of Atopic Dermatitis-Like Skin Lesions by DA -9102, a Natural Medicine Isolated from Actinidia arguta, in the Mg-deficiency Induced Dermatitis Model of Hairless Rats
- Combinatory Mechanisms of TetraA s？？ in Combination with Cytotoxic Anti-cancer Agents against Human Cancer Cells
- Bioactive Constituents from Marine Organisms Inhabiting in Vietnamese Sea
- Regulation of Ceramide-induced p27kip1 Expression by PP2A Activation in PC-3 Prostate Cancer Cells.
- ERK 1/2 Signaling Pathway is Involved in Verproside-Mediated Anti-inflammation in a Mouse Model of Allergic Asthma
- Methylmercury Content of Animal-origin Natural Medicine Determined by Gas Chromatography Electron Capture Detection
- Effect of Xanthohumol on Chronic Oxazolone Induced Dermatitis in Mouse
- The Effect of Natural Products on Collagen Biosynthesis
- The Naturally Occurring Flavolignan, Deoxypodophyllotoxin, Inhibits Lipopolysaccharide-induced iNOS Expression Require Inhibition of NF-kB Activation in RAW264.7 Macrophage Cells
- Pharmaceutical Promotion, Prior Authorization and the Use of Erectile Dysfunction Medications in the Medicaid Population
- Differential Proteomic Analysis of Kidney Toxicity Induced by Cisplatin
- Free-radical Scavenging Activity of Gentiana scabra var. buergeri
- Antiinflammatory Activity of Angelica Dahurica and Rapid Identification of Active Constituent by LC-NMR/MS
- Quality Diagnosis of National Statistics in Healthcare
- Metallothionein-III Protects against 6 -Hydroxydopamine-induced Oxidative Stress by Increasing Expression of Heme Oxygenase-1 in a PI3K and ERK/Nrf2-Dependent Manner
- Nanocrystalline-Silver Impregnated Activated Carbon Matrix with High Activity Antibacterial
- The Association of Internet Addiction with Excessive Daytime Sleepiness in Korean Adolescents
- Determination of Norfloxacin in Human Plasma by High Performance Liquid Chromatography with Fluorescence Detectio
- Electrochemiluninesce-based DNA Detection Using Microelectrode Array
- Construction of Knowledge Based Drug-disease Contraindication Database for Drugs Approved in Korea
- Factors Related to Weight and Album in Affecting Neuropenia in Korea Solid Cancer Patients
- Total Synthesis of (-)-Macrosphelide K
- Evidence of P-glycoprotein (P-gp) Expression In Human Nasal Epithelial (HNE) Cell Monolayers Cultured by Air-liquid Interface (ALI) Method
- Electronically Modified Polymer-Supported Cinchona Phase-lVansfer Catalysts for Asymmetric Synthesis of α-Alkyl-a-Amino Acid Derivatives
- 3-Hydroxymorphinan, the Parent Molecule of GCC1290, Provides Neuroprotection against Glutamateinduced Toxicity
- Protein lyrosine Phosphatase IB Inhibitory Activity of Antimycins Isolated from Actinomycete AN070088
- New Approach to Chiral Oxazolidin-2-one from Oxirane with Use of Chlorosulfonyl Isocyanate and Its A pplication to the Synthesis o f a -(-)-conhydrine
- Inhibitory Effect of THphlorethol-A on MMP-1 Induced by the Oxidative Stress in Human Keratinocytes via ERK and AP-1
- Constituents from the Vines of Lonicera Japonica
- Pyrroloiminoquinones Isolated from a Deep-Water Alaskan Sponge of the Genus Latrunculia
- Total Synthesis of Fhivirucinine Bl
- Characterization of Recombinant a-GIucosidase of Bifidobacterium H-1
- Protective Effect of Nelumbo Nucifera on a Radiation-induced Oxidative Damage in a RAW 264.7 Macrophages Cell and a Quantitative Analysis with Isoquercitrin
- Simultaneous Determination of Flavonoids from Extracts of Nelumbo nucifera Leaves by High-performance Liquid Chromatography
- Genomic Analysis of Statin Treated Rat Skeletal Muscle Cells
- Preparation and Characterization of PLGA Microspheres Containing PEGylated Exendin-4
- Identification of Diarylheptanoid Derivatives from Alnus Hirsuta
- The Standard Protocols for Bioequivalence Test
- Synthesis of Quinazoline Derivatives as Protein Kinase Inhibitors
- Protective Role of Sulfiredoxin in Apoptosis under Oxidative Stress
- Simultaneous Determination of Paeoniflorin,trans-cinnamic acid, Schisandrin and Glycyrrhizin in So-Cheong-Ryong-Tang by HPLC-DAD and HPLC-ESI-MS
- Patent Linkage System in Korea
- Effects of a Novel Propofol Microemulsion on Microbial Growth
- Absorption, Metabolism, Distribution, and Excretion of [14C]BR-A-657 Following Oral or Intravenous Administration to Rats
- 3D QSAR Studies of CK2 Inhibitors Using CoMFA and CoMSIA
- Re-Activation of Insulin Signaling by Adiponectin in Insulin-resistant Cells
- Improvement of Memory Impairment by Ltheanine through its Anti-oxidant and Neuroprotective Effect
- Involvement of the Nrf2 -antioxidant System in Chemoresistance of Cancer Cells
- Protective Effect of Fermented Ginseng (FG) and Cortex cinamomi Extract on Streptozotocin-induced Damage in Rat Pancreas β-cell
- Quantitative Targeted Proteomics as a New Strategy for the Blood-Brain Barrier Research
- Transcriptomic Analysis in the High and Low-Dose Epigallocatechin-3-gallate and Propyl Gallate-treated HepG2 Cells
- Effect of Hinokitiol, a Tropolone Derivative, on TNF-α Production in LPS-activated Macrophages
- Cloning of the Novel Glycoprotein DNA from Erimacrus Isenbeckii
- Involvement of Matrix Metalloproteinase-9 (MMP-9) in ATP-induced Microglial Migration
- Preparation and Characterization of Solid Dispersion of Coenzyme QIO
- Novel Hyaluronan Nanoparticles for Tumor Targeting
- Antioxidant Activities of Different Extracts from Aralia elata Seeds
- Current Status and Future Prospect of Chuncheon Biocluster
- Corynoxeine Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation through the Inhibition of ERKl/2 Activation
- Effects of Tanshinone IIA on the Hepatotoxicity and Gene Expression Involved in Alcoholic Liver Disease
- Separation of Ceramide 1 -Phosphate by Hexane-Ethanol Extraction and Quantification by High Performance Liquid Chromatography
- The Expression of Kainate Receptors and Microtubule-Associated Protein 2 in the Hippocampus of Maternal Separation Rat Pups
- Calorie Restriction Modulates Visceral Lipid Accumulation and Inflammation in Ob/ob Mice
- A Chemoselective Deprotection of Bulky IVialkylsilyl Acetylene by Silver Fluoride
- Anti-proliferative Activities of Benzamide Derivatives
- study on the Risk Assessm ent of the Menstrual Pads and Tampons
- lontophoretic Delivery of Donepezil hydrochloride
- Cimiside E, a Potential Antitumor Natural Product, Induces Cell A poptosis via Fas Sign aling Pathway
- Pharmacokinetic Parameters of Oltipraz in Liver Cirrhotic Rats with Diabetic Mellitus
- Role and Relevance of Membrane Transporters in Pharmacokinetics, Pharmacological Activity, Toxicity and Diseases
- Screening for SNPs and Haplotypes of CYP1A2 Gene in a Healthy Korean Population
- An Analytical Method to Quantify Phytoceramides by High Performance Liquid Chromatography after SCDase Release of Sphingoid Base
- New Isolate of Streptomyces olivochromogenes Producing Extracellular Proteases.
- Isolation, Identification and Quantification of Anti-Oxidative Compounds from Diospyros kaki calyces
- Glycyrol, an Acyl-coenzyme A: Cholesterol Acyltransferase Inhibitor from Licorice Roots
- HlF-l Inhibitors from Morus Species
- Protection of Kainate Neurotoxicity by Ginsenosides: Attenuations in the Convulsive Behaviour, Mitochondrial Dysfunction and Oxidative Stress
- Progress for Standardization of Traditional Medicine, Angelica tenuissima by Isolation and Various Analysis Techniques
- Doxorubicin Nano-micelles Targeted for Epidermal Growth Factor Receptor Overexpressing Tumor Cells
- The Meianogenesis Inhibitory Effect on B16F10 by Periostracum cicadae
- Inhibitory Effects of Stress Factors by Oligonol Supplementation in the Male Subjects
- Clean, Safe, Secure and Efficient Cleanroom Engineering in Pharmaceutical Production
- The Pharmacokinetics of Gabapentin, Levosulpiride, and Risperidone According to the Genetic Polymorphisms of M DRl Gene
- In silico Study of Aurora Kinase Inhibitors Using 3D QSAR and Molecular
- Effect of Administration Routes on the Mucosal and Systemic Immune Responses against Subunit Vaccine in Mice
- Acquired Butyrate Resistance in Human HCT116 Colon Cancer Cells Induces Resistane to Other Anti-cancer Drugs
- Optimization of the Generation Methods for Cytokine-lnduced Killer Cells from Mouse Spleen Cells
- ATR, a S-Phase Checkpoint Kinase Upregulates Chromatin Binding of Cdc6 in Synchronized HeLa Cells
- Meteorin Regulates Neuro-Glial Fate Decision through Induction of BMPs
- The Modulatory Effects of Paeonia Suffruticosa Andrews on the LPS-induced Activation of BV2 Microglial Cells
- The Effect of Siegesbeckia Glabrescens Makino in Nitric Oxide Production on Human Umbilical Vein Endothelial Cells
- Crystal Structure of C12H14O3N2S3
- Quantitative Analysis of Rabeprazole in Human Plasma by LC-MS/MS Using Rapid and Simple Sample Preparation
- Lectin from the Mushroom Cordyceps militaris
- Chungsim-Yeunja-Tang Inhibits the LPS -induced IL-32 Production via Inhibition of NF-kB and Caspase-1 Activation in Peripheral Blood Mononuclear Cells
- The Development of the Doctor of Pharmacy Program in the United States
- Potential Anticancer Agents from Marine Invertebrates
- Discovery and Early Development of SKL11197,a Novel Neuropathic Pain Drug
- Role of the Nrf2 Pathway in Cell Survival
- Distribution of Polymethoxyflavonoid Contents in Jeju Native Citrus Plants and their Physiological Activities
- Analyzing on the Functional Material Studies in Jeju Citrus Industry
- Anti-ulcer Activity of Hydnocarpi Semen Extract on a Traum atic Wound in Streptozotocin Induced Diabetic Mice.
- Synergistic Decrease in Blood Pressure of Candesartan Combined with Lacidipine in Spontaneous Hypertensive Rats
- Anti-inflammatory Effects of Extracts from Jeju Dangyuja(Citrus grandis Osbeck)
- Protective Effects of Citrus Pectin against TCDD Toxicity
- A High-Yield Approach to the Selective Synthesis of D-arabino-, D-lyxo-, and D-xy/o-Phytosphingosiiies from Inexpensive D-ribo-Phytosphingosine
- Tyrosinase Inhibition Study of Bromophenoxyphenylether Analogues
- Analysis of Ginsenoside Composition of Ginseng Flos
- Simultaneous Analysis of Parabens in Cosmetics
- Development of Quantitation Analysis Method of Bamboo Leaf Using Alternative Standards
- Real Time Analysis o f Dihydro-A2E: An Intermediate in the A2E Biosynthesis
- Immune-enhancing effect of Drynariae Rhizoma(DR)
- Efficient Delivery of siRNA Using Hyaluronic acid and Polyethyleneimine Derivatives
- Carbphydrate Analysis on the Glycoproteins Using High-performance Anion-exchange Chromatography with a Pulsed Amperometric Detection
- Studies on the Preparation of Nanoemulsion of a Newly Synthesized Quinazoline for Developing as Skin Whitening Agent
- The Effect of Dibucaine-HCI on Rotational Mobility of n-(9-Anthroyloxy)stearic Acid in Neuronal and Model Membranes
- Measuring Utility Weights for Severe Stomach Cancer
- Oral Exposure to Mercuric Sulfide Alters T Lymphocyte Phenotypes in Mice
- Environmental Toxic Metabolites and Structure Relationship in CNS Neurotoxicity
- Effect of Cotreatment of Pidotimod and Red Ginseng Acidic Polysaccharides on Peritoneal Macrophage Function in Immunosuppressed Mice
- Efficient Method to Enrich Phosphopeptides and Map the Phosphorylation Sites in Phosphoproteins Using Proteomics Technology
- Protective Effect of Caffeic Acid Phenethyl Ester against Carbon Tetrachloride-induced Hepatotoxicity in Mice
- Curry Curcumin Inhibits Mast cell-mediated Allergic Response at the Level of Syk Kinase
- Analysis of KCNEl genes for the SNPs in Korean Genome
- Manassantin A Inhibits cAMP-dependent Melanin Production in Melanoma B16 Cells
- Silencing of Tumor Suppressor RUNX3 by Histone Modification in Hypoxic state Stimulates Angiogenesis in Gastric Cancer
- Induction of Apoptosis by Sulforaphane Analogues in Human Colon Cancer Cells
- Targeting the Ras Oncoprotein for Anti-cancer Drug Discovery and Treatment
- Pharmaceutical Patent Strategy from Litigation Cases
- Mass Spectrometry Based Metabolomic Approach for Biomarker Discovery
- Achiral and Chiral Separation of Chiral Acids, Amines and Amino Acids by Gas Chromatography and Capillary Electrophoresis
- Asymmetric Synthesis of Aminocyclitols as New Glycosidase Inhibitors
- Combined Treatment with Coenzyme QIO and Statin in Hyperlipidemic Rats.
- Analysis of Gliclazide and Nabumetone Related Compounds with HPLC
- Anxiolytic-like Effects of Sanjoinine A Isolated from Zizyphi spinosi Semen
- Anti-inflammatory Activities of Panax ginseng Head BuOH Fraction in Mice
- Eupatilin Protects Gastric Epithelial Cells from Oxidative Damage and Down-regulates Genes Responsible for the Cellular Oxidative Stress.
- Contents of Heavy Metals in Commercial Herbal Medicines in Seoul (2007)
- Synthesis of Benzo[b|oxepine Derivatives, Constrained Form of 3-ArylisoquinoUnes, as Potential Antitumor Agents
- Identification of Genes Differentially Expressed in the MCF-7 Cells Treated with Mitogenic Estrogens
- Isolation of Chemical Constituents from Polyporus
- Anti-inflammatory Effect and HPLC Analysis of Extract from Edible Cirsium setidens Nakai and Its Isolated Compound
- Comparison of the Effects of Bile Components and Total Bile Acids on Cell Viability
- Study on Sell-by-Date of Health Functional Foods;UniBEX™ and Univestin-K
- Parallel Applications of Integrated Circuit Bipolar Semiconductor Microchip as a Miniaturized Sample Platform and a Two-dimensional Photodetector for Optical Detection of Biomolecules
- Protective Effect of glycyrrhiza inflata against High Glucose-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells
- The Estrogenic and Antiestrogenic Action of Epimedii herba in Ovariectomized Rats
- Development and Validation of a LC-MS/MS Method for Determination of Goserelin in Rat Plasma
- P54nrb is a Key Regulator of Tijmor Cell Invasion
- Determination of lndirubin-5-nitro-3'-monoxime in Rat Plasma by Liquid Chrom atography/Electrostray Ionization Tandem Mass Spectrometry
- Target Specific Intracellular Delivery of siRNA/PEI-HA Polyplex
- Strategies for Preserving the Solubility and Activity of T\imor Necrosis Factor-related Apoptosis Ligand Following Freeze-Drying
- Three-layered Tablet with Poly(Ethylene Oxide) Core M atrix Capped by Carbopol: Solid State Characterization and Dissolution
- Pharmacokinetic Characteristics of lontophoretic Levodopa and Carbidopa Formulation in Rats
- Block Inomer Complexes as Prospective Nanocarriers Nanocarriers for Drug Delivery
- Preparation and Evaluation of Solid Lipid Nanoparticles Using a Newly Synthesized Quinazoline
- Cationic Liposome-mediated Delivery of Therapeutic Genes
- Dioleoyiphosphatidic Acid Induces Morphologic Change in an Endogenous LPA Receptor-dependent Manner in C6 Glioma Cells
- Genetic Toxicity Test of Tetrachloroethylene by Ames, Micronucleus, Comet Assays and Microarray Analysis.
- Screening of Small Molecule Inhibitors of XIAP/Caspase-3 Interaction Using Protein Chip (Cl-chipver1.0)
- The G12 Family Proteins Upregulate MMP-2 Leading to Human Breast Cell Invasion
- Identification of Differentially Expressed Genes in Mouse During Hypoxia Using Annealing Control Primer System
- Isolation and Biochemical Characterization of Bioactive Lysine-iype Peptidoglycan Fragments from Staphylococcus aureus Cell Wall Components
- Syk is Responsible Kinase for Regulating Early Phosphorylation of IkBα
- Molecular Cloning and Heterologous Expression of Novel Channel-like Protein, TMEM16D
- Development of in vitro Toxicity Methods, which Alternate in vivo Assay at an Early Stage of Drug Discovery
- Physiological Functions of Src-Family Kinase Isoforms,Lyn, Fyn, Fgr, and c-Src on Degranulation in Mast Cells
- Novel Quinazoline JSH-18 Inhibits Melanin Production in B16 Melanoma Cells
- Inhibitory Effect of Chalcone JSH-1144 on Interleukin-3-dependent Proliferation of Pro-B BaF/B03 Cells
- Eckol Protects V79-4 Cells Against G-Ray Radiation-Induced Apoptosis via the Scavenging of Reactive Oxygen Species and Inhibiting of the C-Jun NH₂-Terminal Kinase Pathway
- The Change of Ginsenoside Composition in Ginseng Extract by The Ascorbic Acid Process
- Isolation of Compounds from Cnidii Fructus
- Lipopolysaccharide Modulates Tissue Plasminogen Activity through the Regulation of Plasminogen Activator lnhibitor-1 in Rat Astrocyte
- In Vitro Anti-inflammatory Activity of 3-0-methyl-flavones Isolated from Siegesbeckia Glabrescens
- Non-viral Gene Therapy Carrier Employing Poly (ethylene imine)-poly(ethylene glycol) grafted Chitosan
- First Asymmetric Synthesis of Optically Active H₁Receptor Antagonist Clemastine
- Antioxidant Compounds from Ilex cornuta L.
- Synthesis and Antioxidant Activity of 3,4,5-TVihydroxy-N-(2-hydn)xyphen}iethyI)benzainides(TH-HPEBA)
- Vascular Smooth Muscle Dysfunction Induced by Ginsenoside Rg3, a Bioactive Component of Ginseng
- Development of Atopic Dermatitis-Like Skin Lesion with Dermatophagoides Farinae Extracts in Immune-imbalanced BALB/c Mice
- Discovery of Novel Nuclear Factor (NF)-kB Inhibitors Using Chroman Carboxamide Derivatives
- Approaches Needed for Toxicity Testing of Nanoparticles
- Development of CG100649, a Next Generation NSAID
- Studies on the Preventive Effects of Fruit of Broussonetia papyrifera(L.) Vent on Osteoporosis.
- Application of Toxicogenomic Technology for the Improvement of Risk Assessment
- Protective Effects of the Water Extracts of Hovenia Dulcis Thunb against Ethanol-induced Toxicity in Primary Cultured Rat Hepatocytes
- In hibition of Transforming Growth Factor-β1 induced Hepatic Fibrosis by Gα12 / Gα13 Deficiency
- First Synthesis and Unusual Conformation of 4"-Selenonucleosides
- Review on the Clinical Pharmacy Education in the U.S.A.
- Current Situation and Issues on the Pharmacist in Japan
- Statistical Analysis and Safe Use of Drug Following by Adverse Drug Reaction
- Analysis of Polypharmacy and Related Factors
- Sialylated Oligosaccharide Analysis on the Glycoproteins Using a High-performance Liquid Chromatography with a Fluorescence Detection
- Determination of Aceclofenac in Human Plasma by HPLC/UV
- Analysis of Prescriptions for the Elderly at Primary Health Care Using National Health Insurance Database
- Review : Characteristics of Various Pharmacokinetic/Pharmacodynamic Models
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