학술논문
Discovery Strategy of SKL11197 for Novel Neuropathic Pain Drug
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- CHAE Eun Hee KWAK Byong Sung CHO Jeong Woo YI Han Ju CHAE Sang Mi SHIN Hye Won LEE Sung Hak KOO Tae- Sung CHO Hyeon JUNG Ji Young LEE Ju Young KANG Young Soon HONG Seok Cheon KIM Sung Hong KOH Hye Jin BAEK Myoung Ki NAM Hyun Sik PARK Jung Shin KANG Chang Gyun IM Dae Joong RHO Tai Kyun KIM Min W oo KIM Hong Wook MELNICK Susan LEE SJames MOON Hong Sik
- 간행물 정보
- 『춘계총회 및 학술대회』(2008년) vol.1A, 221~221쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2008.04.30
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- Isolation of Five Compounds from Asiasari Radix
- Antioxidant Activity of Fractions from Sonchus oleraceus L. 70% Methanolic Extract
- Biochemical Characterization of Novel Three Serine Protease Inhibitors (Serpins) Involved in Toll Signaling Pathway of Tenebrio molitor Larvae
- Ursodeoxycholic Acid Regulates NF-eB and STAT Pathway of T- and B Cell-lines
- Validation of Analytical Method for Determina-tion of Tilianin in Agastache rugosa by HPLC
- Involvement of Calpain and Cathepsin in the Cleavage of Collapsin Response Mediator Protein-2 and Its Implication in the Neuronal Cell Viability under Ischemic Condition
- Magnolol Isolated from Magnolia obovata Enhances Pentobarbital-induced Sleeping Behaviors
- Allylmethylsulfide Inhibits Activation of NF-kB Signaling Induced by X-ray Irradiation in C57/BL6 Mice Kidney
- Chalcones from A ngelica keikei and their IL(interleukin) - 6 Inhibitory Activity
- Comparative Studies on Anti-inflammatory Effect of Angelica dahurica Root and Fermented A. dahurica Root in Raw264.7 Cell
- Gastroprokinetic Effects of DA-0701 , a New Prokinetic Agent Form ulated with Pharbitis Semen and Corydalis Tiiber
- Discovery of New Antagonists of GSK3b-Axin2 Interaction
- Design, Syntheses and Biological Evaluation of Novel TRPVl Antagonists
- Inhibitory Ability of Thiacremonone on the Activated NF-kB Enhances Susceptibility of Colon Cancer Cells to Docetaxel
- The Anti-inflammatory Effect of Chrysophanol in Mouse Peritoneal Macrophages
- Activation of ERK 1/2 and PI3K-Akt Pathways by CCL2 in the Primary Cultured Rat Cortical Cells
- A Studies on the Instrumental Analysis of Antibiotic Drugs
- The Analysis of Volatile Components of Processed Ginseng
- JNKl-Mediated Phosphorylation of Smac/ DIABLO is Functionally Linked to its Mitochondrial Release during TNF-a-Induced Apoptosis.
- Comparative Effects of Hypochlorite and Hydrogen Peroxide on the Relaxation of Esophageal Smooth Muscle of a Cat
- Improved Synthetic Methods for Pyranose-Annulated Natural Products
- Chemical Constituents Isolated from Polygala japonica Leaves and Their Inhibitory Effect on Nitric Oxide Production in Vitro
- A Facile Methods for the Functionalization of Peri-Position of Heteroaromatics: Utility of Acetates as a Potential Catalyst for Aldol-type Reaction
- Lipid Metabolism and Liver Protection of Vaccinium uliginosum L. in Ethanol Fed Rats
- Acrylamide Induces Apoptosis In Neural Progenitor Cells And Impairs Hippocampal Neurogenesis
- Temperature-dependent Volume Transitions, Cytotoxicities, and Gene IVansfection Efficiencies of Pluronic Decorated-nanogels for in vitro Usages
- Evaluation of Total Oxyradical Scavenging Capacity of Platycodon grandiflorum
- Honokiol Isolated from Magnolia obovata Potentiates Pentobarbital-induced Sleeping Behaviors through GABAΑ Receptors Activation
- The Synthesis and Anticonvulsant Evaluation of 6-amino-1,4-oxazepane-3,5-dione Derivatives
- Postmortem Determination o f Ethylene Glycol and Gycolic Acid by Gas Romatography-M ass Spectrometry in Human Specimens of a Cute Poisoning
- Inhibitory Effects of Obovatol, a Biphenolic Component of Magnolia Obovata, on Rat Arterial Thrombosis and Platelet Aggregation
- Efficacy and Safety Study of PurinoITM
- The Essential Components of Fungal β-1,3-Glucan Dependent Toll Signaling Pathway in the Mealworm, Tenebrio molitor Larvae
- Analysis of Methamphetamine and Amphetamine in Oral Fluid of Twelve Drug Abusers Using Solid-Phase Extraction and GC-MS
- The EfTect of Tanshinone I on Memory Relating ERK Signaling Pathway
- Protective Effects of Paecilomyces tenuipes Against Carbon Tetrachloride-induced Toxicity in Primary Cultured Rat Hepatocytes
- A Cell Based Screening for Wnt/β-catenin Pathway Inhibitors in Non-small-lung Cancer Cell Lines
- Synthesis of Mansonone F 01 Analogues and their Anti-MRSA Activities
- Regulation of Dihydrosphingosine-l-phosphate Release in F9 Mutant Cells by Fumonisin B₁
- Enhancement of Platelet Activation and Thrombus Formation by Silver Nanoparticles
- Anti-inflammatory Activity of an Ethanol Extracts of Saururus chinensis in an Animal Asthmatic Model
- Effects of L-Tetrahydropalmatine on Conditioned Place Preference and Locomotor Sensitization Induced by Methamphetamine
- Microarray Profiling Reveals Calcium-binding Proteins S100A8 and S100A9 as Candidate Markers for Invasive Human Breast Epithelial Cells
- Capsaicin Inhibits EGF-induced Migration and MMP-9 Activity in Lung Cancer Cells through ERK-, JNK and AP-1-dependant Signaling Pathway
- The Supramolecular Assembly of the Tripartite Multidrug Efflux Pump of Gram-negative Bacteria
- Cadmium Induced Gene Expression Changes in Human Lung Fibroblasts
- Protection of MPTP Dopaminergic Toxicity by EGb 761, a Standard Extract of Ginkgo Biloba; Involvements of Anti-inflammatory Action, Inhibition of PAF-Receptor, and Induction of PAF Acetylhydrolase
- Neuroprotective Effects of Sulforaphane Against a- Amyloid-Induced Cell Death and Memory Impairments
- Role of Protein Kinase C-5 as a Regulator of Hypoxia-Induced Angiogenesis
- Analytical Method of Oxidation Dye Components in Hair Dyes
- In vivo Pharm acological Characteristics of a Novel PPARg Modulator, PAM-1616
- The Effect of KH-red Ginseng Mixture Supplementation upon the Immune Response of Mice
- Synthesis and Cytotoxicity and Topoisomerases Inhibition of New Xanthone Analogues
- Inhibition of Diacylglycerol Acyltransferase by Phenylpyropenes Produced from Penicillium griseofulvum F1959
- Effect of Prenatal Administration of Polybrominated Diphenyl Ethers (PBDEs) on the Thyroid Hormone Levels and Neuronal Development in Juvenile and Adult Rats
- Comparison of Different IMAC Techniques for Quantitative Analysis of Sphingoid Base-l-Phosphates
- Polybrominated Diphenyi Ether (PBDE) and Thyroid Hormone Levels in Cord Blood of Infants in Korea
- Genexol-PM, a Polymeric Micellar Paclitaxel Formulation as Monotherapy or in Combination with Gemcitabine in Xenograft Model of Pancreatic ASPC-1 Carcinoma
- Activity Change of Sphingomyelin Catabolic Enzymes during Dimethylnitrosamine-induced Hepatic Fibrosis in Rats
- Compound K Inhibits Intracellular Triglyceride through AMPK Activation in HepG2 Cells
- Effects of Antioxidizing Activity, Anti-Platelet Aggregation Capacity and Stability of Anthocyanins from Blueberry, Cranberry and Red Cabbage.
- Quantitative Determination of Eleutheroside E from Preformulation Products of Acanthopanax Koreanum by HPLC
- Estimating Kidney Function in Children with Growth Retardation through Analysis of Vancomycin Pharmacokinetics
- Quantitative Analysis of Major Active Components from Astragali Radix by HPLC
- Mosquito Repellent Activity of DEET Analogues Determined by a New in vitro Assay
- Enhanced Bioavailability of Etoposide after Oral or Intravenous Administration of Etoposide with Kaempferol in Rats
- Quantitative Analysis of Major Active Components from Ostericum Radix by HPLC
- Effect of Astaxanthin on the Methamphetamine-Induced Neurotoxicity
- Pharmacokinetics and Tissue Distribution Profile of Doxorubicin Given Intratumorally Using Thermosensitive Hydrogel
- The Role of Peroxisome Proliferator Activated Receptor-α and Akt-Mediated 5'AMP-Activated Protein Kinases on the Fatty Liver induced by Orotic Acid
- Method Development for Quantitative Analysis of Isoorientin and Baicalin in UniflavonTM
- Effect of p-Glycoprotein on the Tissue Dstribution of DHP107, Oral Paclitaxel Formulation
- A Quassinoid 6α-Tigloyloxychaparrinone Inhibits Hypoxia-inducible Factor-1 Pathway by Inhibition of Eukaryotic Translation Initiation Factor 4E Phosphorylation
- The Effect of Heat TVeatment on the Phenolic Acid Contents and Antioxidant Activity of Inonotus Obliquus
- Effects of the Korean Pears, ly r u s pyrifolia cv. shingo, on Alcohol Detoxification in Aldh2-/- Mice
- The Effects of Litsea japonica on the Apoptosis Induction in the HL-60 and HL-60/ADR
- Effects of Flower and Stalk from Prunella vulgaris on the Macrophage Functions
- Neuroprotective Constituents of Dictamnus dasycarpus Root Bark
- Novel Piperazinylpropyipyrazole Derivatives as Dopamine D4 Receptor Antagonists with Therapeutic Potential for Schizophrenia
- Anti-obese Activity of Novel Cannabinoid- 1 Receptor Inverse Agonist GCC2680 in Mice
- Suppression of Inducible Nitric Oxide Synthase by Naphthoquinoids from the Bulbs of Eleutherine Americana
- Platelet Anti-aggregatory, Anti-coagulant and Vasorelaxation Effects of Compounds Isolated from Cinnamomi Ramulus.
- D/L-Configuration of Amino Acids in Peptides with Edman Degradation and Circular Dichroism
- Discovery Strategy of SKL11197 for Novel Neuropathic Pain Drug
- Food Consumption Increases the Systemic Exposure of Niflumic Acid Following Oral Administration of Talniflumate
- Patient Self INR Monitoring of Oral Anticoagulation
- The Effect of Dispensing Error Prevention Program on the Incidence of Dispensing Error in Hospital Pharmacy
- Development of an in vitro Test System Measuring Transcriptional Down-regulatory Activities on IL-13
- Anti-diabetic Activity of a Novel Cannabinoid- 1 Receptor Inverse Agonist GCC2680 in Mice
- Antiobesity, Antihyperlipidemic, Hypoglycemic Effect of the Black and Green Tea Supplementation on Hyperlipidemic-induced Diabetic Rats
- Comparative Study on the Regulations of Controlled Substances
- Guideline on Evaluation of Clinical Trials in Korea- Neuropsychological Drug
- Dose-dependent Pharmacokinetics, Hepatic and Gastrointestinal First-pass Effects, and Hepatic CYP Isozymes Responsible for Metabolism of Mirodenafil, a New Erectogenic, in Rats
- Cognitive-Enhancing Activity of Decursin Derivatives
- Evaluation of the Use of HMG -CoA Reductase Inhibitors for the Patients with Renal Insufficiency in a University Hospital
- Bergamottin Suppresses PMA-mediated Matrix Metalloproteinase-9 Activation through Down-regulating Nuclear Factor-kB
- Development and Optimization of a Novel Sustained-release Tablet Formulation for Bupropion Hydrochloride Using Box-Behnken Design
- Anti-Stress Effect of Korean Red Ginseng on Immobilization-Stressed Mice via PADI4, a Stress Marker
- Nucleolin : Another Role as a Receptor of Acharan Sulfate
- Prunus yedoensis Barks Inhibit the Inflammatory Chemokines (MDC & TARC ) in IFN-γ Stimulated HaCaT Keratinocytes
- Apoptosis-inducing Activity of 2 ,4,6-Trihydroxy-2-Geranylacetophen one in Adriamycin -Resistant MCF -7 Breast Cancer Cells
- Biochemical Characterization of the Smallest Class IV Adenylyl Cyclase from Yersinia pestis
- Antiproliferative Effect of Fisetin on Rat Aortic Vascular Smooth Cell by Gl-Cell Cycle Arrest
- Induction of Inflammation Signals by Silica Nanoparticle in Murine Macrophage Cell Line, RAW 264.7
- Antiproliferative Activity of JY0691, a Newly Synthesized Obovatol Derivative, on PDGF-BB-stimulated Rat Aortic Vascular Smooth Muscle Cells
- Surfactin from Bacillus subtilis Acts as a NF-kB Inhibitor in Inflammatory Conditions
- Molecular Control and Antibacterial Activity of Phenoloxidase-Induced Melanin Synthesis in Larvae of the Beetle, Tenebrio Molitor
- study on the Inhibitory Effect of GS Extract on Aβ Oligomer-induced H19-7 Cell Death Model and Drosophila Model of AD
- Sophoricoside Inhibits 2,4-Dinitrochlorobenzeneinduced Contact Dermatitis in Balb/c Mouse
- Shizukaol B Inhibits the Immune Functions of B Cells, but not T cells, Macrophages, and Dendritic Cells
- Effect of Ochnaflavone on Septic Arthritis Due to Candida albicans
- Evaluation of the Adjuvant Activity of CIA07 to Anthrax Protective Antigen
- Antifungal Effect of Glycyrol, a Component of Glycyrrhizae Radix, against Candida albicans
- Abnormalities in Regulation and Interaction of Lymphocytes in the Pristane-Induced Lupus Mice
- Akt Up-regulates Smac Activity by Phosphorylation during Etoposide-induced Apoptosis of HeLa Cells
- Bovine Lactoferrin Inhibits OVA-Specific Allergic Responses
- TP 53 Restoration Using Combined Cisplatin and E6/E7 siRNA Leads to l\im or Regression in Cervical Squamous Cell Carcinoma
- The Crosstalk between Wnt2 and ERK Pathway in Non-small-cell Lung Cancer Cell Lines
- Hyperoside Prevents Oxidative Damage Induced by Hydrogen Peroxide in Lung Fibroblast Cells via an Antioxidant Effect
- Xylocydine Induces Apoptotic Cell Death of Hepatoma Cells by Inhibiting CDK
- Rapamycin, mTOR Inhibitor, a Potent Cell Growth and Proliferation Inhibitor by p21-Dependent Mitotic Arrest in Human Gastric Cancers
- Cloning and Functional Analysis of 5'-flanking Region of Metastasis-Associated 1 Gene
- Triterpenoids from Leaf of Diospyros kaki and their Inhibitory Effect on Protein Tyrosine Phosphatase IB
- Isolation and Antioxidant Ability of Phenolic Compounds from Geranium nepalense var thunbergii
- The Sulindac Derivatives Bind α₁-antitrypsin
- Inhibitory Effects of Chromatographically Fractionated Extracts from Chrysanthemum zawadskii on Tyrosinase Activity and Melanogenesis
- Protective EfTect of Butanol Fraction of Phaleria macrocarpa On Oxidative Stress Associated with Streptozotocin Induced Diabetic Mice
- Action Mechanism of HTIO in Biophysical Perspectives: HTIO Binds to VEGF Strongly and Causes Severe Structural Changes
- Oxaliplatin-induced Peripheral Neuropathy in Patients with Advanced or Metastatic Gastric Cancer
- Pharmacokinetic Interaction between Telithromycin and Metformin in Rat Model of Diabetes Mellitus Induced by Streptozotocin
- Comparative Study on the Regulations of Biological Medicinal Products
- Gai-Mediated LDL-Induced Aortic Smooth Muscle Cell Proliferation
- Salsolinol, an Endogenous Neurotoxin, Enhances Platelet Aggregation and Thrombus Formation
- Cellular Mechanism of the QT-Prolongation Induced by Sulpiride
- Propenone Derivatives Inhibit Vascular Endothelial Growth Factor-induced Agiogenesis in vitro and in vivo
- Apoptosis Inducing by Sesquiterpenes Isolated from Magnoliae obovata
- Co-delivery of Curcumin and Daunorubicin via Liposomes for Synergistic Anticancer Effects
- Identification o f hFAFl Binding Proteins; NPL4 and UFDl are Interacting with hFAFl via VCP
- Strategy for the New Drug Development in Korea
- Rapid and Sensitive Determination of Losartan in Human Plasma by LC-ESI/MS/MS
- Formulation of Cationic Liposome Gel for Amphotericin B
- Effects of Hwang-ryun-hae-dok-tang on the Pharmacokinetics of Phenolsulfonphthalein, a Model Organic Anion Drug
- Renovation of Pharmacy Education in Japan - A Key Role of On-site Pharmacy Training
- Nicotine Attenuates Both iNOS and nNOS Involved Antioxidative Effects and Contributes to Neuroprotection in Spinal Cord Injury
- Immunological Adjuvant Effect of Cudrania tricuspidata on the Immune Responses to Ovalbumin in Mice
- Pre-pharm Courses for PEET and Admission Guideline in Korea
- Study of a Proposed Korean National Biological Standard of Human Anti-Hepatitis B Immunoglobulin for Potency Test
- Neuroprotective Effects of Licochalcone E from Glycyrrhiza Inflata Involves Anti-inflammatory and Anti-Oxidative Activity
- AKT Up-regulates the Interaction of Osterix with Osterix-Binding Partners and Transcriptional Activity
- Sirt2 Acetylation by Acetyltransferase p300 Attenuates Its Deacetylase Activity
- Functional and Structural Studies of Secretagogin,Novel Calcium Binding, Using Proteomic Analysis
- Protective Effects of Paeoniflorin Against LPSinduced Cytotoxicity and Genotoxicity in MTT and Comet Assays
- Effect of Horse Bone Extract on the Osteoporotic Factors in vitro and invivo
- Thl/Th2 Cytokine Modulation in Human PBMC by Acanthopanax divaricatus var. albeofructus
- The Quantitative Analysis of Rutin in Mori Folium by High-Performance Thin-layer Chromatography(HPTLC)
- Quantitative Analysis of Schizandrae Fructus Based on the Origin by HPLC
- The Effect of Herbal Extracts on Osteoclasts
- Down-regulation of the Organic Cation Transporters of Rat Liver and Kidney in Ethynylestradiolinduced Cholestasis
- PCRW Inhibits Catecholamine Secretion from the Isolated Rat Adrenal Medulla
- Effect of Morin, a New Flavonoid, on Liver Damage in Rats with Dimethylnitrosamine-induced Cirrhosis
- Development of an Anti-inflammatory Bio-therapeutic
- Inhibition of NF-kB by Ginsenoside Rg3 Enhances the Susceptibility of Prostate and Colon Cancer Cells to Docetaxel
- Exploring Marine Bacteria Associated with a Marine Ascidian in the East Sea and their Secondary Metabolites Production
- Phospholipase D from Streptomyces Tendae with Hydrolytic and IVansphosphatidylation Activity.
- Inhibition of Dual-Speciflcity Protein Phosphatases (DUSPs) by NSC-87877
- Synthesis, SAR and Evaluation of 4-Substituted Biaryl Pyrazoles as CBl Cannabinoid Receptor Antagonists
- Synthesis and Structural Activity Relationship of Benzoxathiol-4-one Analogues as Inhibitor of NF-kB Activation
- Synthesis and Hypnotic Activities of 7V-Cbz-αaminoglutarimidooxy Carboxylate Derivatives
- Synthesis of o-Carboranylphenols as Potential BNCT Agent
- Synthesis of Terpyridine Bioisosteres and Evaluation of their Antitumor and Anti-inflammatory Activity
- Novel Ligands of Peroxisome Proliferator-Activated Receptor Delta for IVeatraent of Obesity
- Novel HDAC Inhibitor, KBH-A145; Synthesis and Biological Evaluation
- Synthesis of 2-thienyl-4-furyI-6-aryl-pyridinederivatives and Evaluation of their Antitumor Activity
- Isolation of Compounds from Seeds of Plantago asiatica L.
- RCM Application for the Totoal Synthesis of Natural Protoberberine Alkaloids
- Synthesis of 2-Substituted-5,8-Dimethoxy-l,4-Naphthoquinone Analogues and Their Inhibition of ACAT
- Novel Anticancer Substance from The Insect-Flower, Cordyceps militaris
- Effect of Pectolinarin on the Production of Pro-Inflammatory Cytokines
- Isolation and Identification of Antioxidant Compounds from Agrimonia pilosa
- Improved Quality Control Method for Scrophularia spp. by HPLC-DAD and Discriminant Analysis for Classification
- The Chemical Constituents of the Stems and Leaves of Rhus sylvestris
- Phytochemical Constituents from Flowers of Clerodendron Trichotoinum
- Antioxidant and Antiinflammatory Components Isolated from M outan Radicus Cortex
- Novel Dimeric ent-Kauranoids from Isodon excisus
- Study on Antioxidant Constituents of Vietnam Bitter Tea Ilex kudingcha
- Oligostilbenes from the Root of Caragana sinica
- Ginsenoside Rb2 Inhibits Gluconeogenesis in HepG2 CeUs via AMPK Phosphorylation
- Anti-Oxidative and Nitric Oxide Production Inhibitory Effect of Wood Vineger from Korean Red Pine(WVK)
- Hyperlipidemic Inhibitory Activity of Chungkookjang
- Hepatoprotective Effect of Acteoside-1 isolated from Acer termentosum Max on D-galactosamine induced Liver Injured Rats
- Inhibitory Constituents of Aldose Reductase from Glycyrrhizae Radix
- Capillary Electrophoretic Separation of PEGylated Granulocyte-colony Stimulating Factor
- Simultaneous Analysis and Quantification by High Pressure Liquid Chromatography of Preservatives in Commercial Pharmaceuticals
- Proteomic Strategies for Identifying Sumoylated Proteins and Sumoylated Sites.
- Metabolic Profiling Analysis of Fatty Acids in Lipids and Free Fatty Acids as tert-Butyldimethylsilyl Derivatives by Gas Chromatography
- Phorbasins D-F: Three New Diterpenoids from the Marine Sponge Phorbas sp.
- The Anti-oxidative Activities and Separation of Extracts from Galla Rhois
- Removal of Herbicides Using Surface Engineered Carbon
- Combining Several Experimental Data from Coffee as an Effective Discrimination Tool in Metabolomics
- Tanshinone II A Induces S Phase Cell-cycle Arrest and Apoptosis in Activation of R at Hepatic Stellate Cells in vitro
- Stability Study of Megestrol Acetate Oral Suspension by Dispersion Optical Analyser
- Development of Valsartan-loaded Solid Dispersion with Spray Drying Method Using Gelatin and HPMC2910
- Effect of PEGylated Liposomal Cromolyn in Pancreatic Cancer
- Enhanced Solubility and Dissolution of Sibutramine Using Solid Dispersion Prepared with HPMC2910, Poloxamer 407 and Citric Acid
- Electrotransport o f levodopa: Electrorepusion vs Electroosmosis
- Characterization of Sustained Release Tablets Containing Solid Dispersion Granules
- Plasma Pharmacokinetics o f 2'-Benzoyloxycinnamaledhyde, an A ntitum or Drug Candidate, in Rats
- Studies on the Physicochemical Characteriazaiton of Dexibuprofen Loaded Organic Gel Formulation.
- Prevention and Therapeutic Effects of Hydrolyzed Products of Aloe vera for Atopic Dermatitis of NC/Nga mice induced D. pteronyssinus
- Topical Formulation of Pine Bark Extract (Pinexol？？)
- Small Interfering RNA Transfection Using New Cationic Lipid-based Liposomes
- TVansport and Metabolism of JAC106, an NO Donor-containing Tubulin Binding Agent, in Caco-2 Cells
- Effect of M DRl Genetic Polymorphisms and Intrasubject Variabilities on the Pharmacokinetics of Levosulpiride in Multi-occasion Studies
- Bioequivaience Evaluation of Cefprozil 250 mg Tablets in Healthy Male Korean Volunteers
- Dose-independent Pharmacokinetics of Liquiritigenin after Intravenous and Oral Administration to Rats: Contribution o f Hepatic and Gastric First-pass Effect to Low Bioavailability in Rats
- Sensitive Determination of Amoxicillin in Human Plasm a by Liquid Chromatography-Tamdem Mass Spectrometry
- DA-9701, a Herb-based Prokinetic Agent, Provokes Pacemaker Currents in Interstitial Cells of Cajal from Murine Small Intestine
- Inhibitory Effect of Salidroside and Tyrosol from Rhodiola Sachalinensis on Meianogenesis
- Deformable Liposomes for Percutaneous Delivery of Conjugated Linoleic acids
- Arraypedia: A New Integrated Database of Microarray for Virtual Validation of Anti-cancer Target Candidates
- Plasma Pharmacokinetics and Tissue Distribution of Genexol？？-PM in Xenografted H460 Nude Mice
- Activation of the Genomic Estrogen Receptor Pathway by Water Extracts of Cirsium Japonicum
- Protection Against Ethanol-Induced Liver Injury and Impaired Metabolomics of Sulfur-Containing Substances by Betaine Supplementation
- U-shaped Dose Response in Vasomotor Tone: A Mixed Result of Heterogenic Response of Multiple Cells to Xenobiotics
- Pharmacological IVeatment of PPARdelta Agonist Promotes Physical Endurance
- Toxicoproteomics: Identification of Biomarkers by Serum Glycoproteom Analysis in Mercury TVeated Mouse Using Nano UPLC Q-TOF Mass Spectrometry
- Inhibitory Effect on Replication of Enterovirus 71 of Herb Methanol Extract
- Superior Dopaminergic Neuroprotective Effect of Phenidone, a Dual Inhibitor of Cyclooxygenase and Lipoxygenase
- The Effects of Isoquinoline Compounds against APP Metabolism
- Overexpression of Program Death-1 Gene in T cells Prevents Streptozotocin-induced Type 1 Diabetes
- Effect of Cinnamaldehyde on Macrophagemediated Inflammatory Responses
- hARD l235 Supports Cellular Growth through AP-1 Transactivation
- Bioactive Flavonoids on Alcohol Metabolizing Enzymes from Echinosophora koreensis
- Hypoxia Induces Epithelial Cell Proliferation by Downregulation of a T\jmor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal motifs (RECK) through
- Screening and Development of Peroxiredoxin Inhibitors as Anticancer Agents
- Discoidin Domain Receptor 1 Mediates Oxidative Stress-induced Cell Death
- Novel Chalcone JSH 04-4 Inhibits Nuclear FactorkB Activation and Inflammatory Mediator Production in LPS-Activated Macrophages
- High-level Expression and Purification of the Chemokines Fused with Maltose Binding Protein in Escherichiacoli (E, coli)
- In vitro Pharmacological Characteristics of a Novel PPARy Modulator, PAM-1616
- Reduced Anxiety in the Transgenic Mice Expressing Presenilin 2 Mutation
- Study of Novel Mechanism of Tumor Suppressor Gene, SMAD4 in Gastric Carcinoma
- Therapeutic Anti-VCAM-1 Antibody Development
- The Supramolecular Assembly of the Tripartite Multidrug Efflux Pump of Gram-negative Bacteria
- Topical Formulation of a Newly Synthesized Molecule Based on the Preformulation
- Introduction: Overview of Physiology of Oxidative Stress and GPCR-G Protein Signaling
- Phagocytic Removal of Apoptotic Cells in Drosophila: Identification of a Receptor and a Ligand
- Gene Expression and Functional Characterization of a Novel Cation Transporter PMAT in the Rat Blood-Brain Barrier
- The Potential Anti-Gastric Diseases Activities of Gardenia jasminoides Ellis and its Constituents
- Total Synthesis of Glycyrol
- structure Activity Relationship of Anti-Inflammatory 2',4',6'-Tris(mettioxymetfioxy)chalcone Derivatives
- Novel Synthesis of Methylene Bridged Isomeric Nucleoside Analogues with Flexible Conformations
- Antibacterial Butenolides from a Korean Marine Tunicate
- Isolation and Identification of Components from Polygonati odorati Rhizoma
- IViterpenoids Isolated from the Roots of Aucuba japonica and their IL (interleukin) - 6 Inhibitory Activity
- Minor Constituents from Anemarrhena asphodeloides
- Constituents from the Flowers of Lonicera Japonica
- Two New Lupane Glycosides from the Leaves of Acanthopanax Koreanum
- Chemical Constituents from Acer tegmentosum
- Cytotoxicity Activity Constituents from Aceriphyllum rossii
- Anticancer Activity on NCI-N87 Cells of Buthanol Fraction from Picrasma Quassioides (D. Don) Benn.Methanolic Extract
- Guideline for Non-clinical Efficacy Tests of Antihyperlipidemic Herbal Medicinal Products
- Chromatographic Enantiomer Separation of N -Benzyloxycarbonyl Amino Acids and Their Ester Derivatives on Covalently Immobilized and Coated Chiral Stationary Phases Based on Polysaccharide Derivatives
- Measurement of Dopam ine, Their Metabolites and Serotonin by High Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate
- Application of NIR to Quality Control of Plant Extracts
- Enantiomer Resolution and Its Application Using a New Covalently Bonded Chiral Stationary Phase Derived from Cellulose Tris(3,5-chlorophenyIcarbamate) in HPLC
- Development of an Analytical Method for the Determination of Residual Nitrovin in Livestock Products using HPLC/UV
- Development of a Novel Sustained-release Tablet Containing Doxazosin Mesylate
- Development of Self-micro Emulsifying Drug Delivery Systems (SMEDDS) o f Coenzyme Q10 for Functional Food
- Effect of Microneedle on the Pharmacokinetics of Ketoprofen from Its Transdermal Formulations
- Erythrocyte Ghosts for Delivery of Antisense Oligonucleotides
- HPLC Method for the Analysis of Doxorubicin in Mouse Plasma and Tissues with Minimal Sample Size Requirement
- Controlled Release of Cyclosporin A Using Nanostructured Lipid Carriers
- Preparation and Characterization of Polyvinyl alcohol/Chitosan Gel-matrix Based Wound Dressing Systems Containing Minocycline Hydrochloride
- Pharmacokinetic Parameters of Oltipraz in Liver Cirrhotic Rats with Diabetic Mellitus
- Influence of Quercetin on the Pharmacokinetics of Phenolsulfonphthalein in Rats
- Proteomic Analysis of Human Peritoneal Mesothelial Cells Treated with TGF-βl
- NF-kB Activation is Involved in Tetrahydrobiopterin-induced Dopaminergic Cell Death
- Purification and Organic Synthesis of a Novel Neuroprotective Compound (SP-8203) from the Earthworm,Eisenia andrei
- Anticancer Effect of Mcl-l siRNA Against Hepatoma Cells
- Hepatic Toxicity of Perfluorooctanoic Acid in Mice
- Establishment of a GFP-HIF l a Stable Cell Line for Assessment of Carcinogenicity of Chemical Toxins
- Potentiation of Ethanol-Induced Liver Injury and Impairment of Sulfur-Containing Substance Metabolomics in Gpx-1 /Cat Mice
- The Effects of the Seed of Cassia Obtusifoiia on Cerebral Global Ischemia in Mice
- Development of an Assay System for the Screening Anti-Allergy Drugs Through Cytokines of Rat Basophilic Leukemia (RBL)-2H3 Mast cell On Ab-Ag Stimulation.
- Modulation of Age-related Vascular Inflammation by Calorie Restriction and Betaine Treatment
- Identification and Functional Analysis of Meteorin in Zebrafish CNS Development
- α-Tocopheryl Succinate Inhibits Prostaglandin E2 Production and Cyclooxygenase Activity in Macrophage cells
- Regulation of Platelet Aggregation by a Reactive Oxygen Species (ROS)-mediated Signaling Network
- Sulfiredoxin Translocates to Mitochondria and Regulates Reduction of Sulfinic Peroxiredoxin III under Oxidative Stress
- Composition of Proteins Located at Plasma Membrane and Exosome from Kidney Tissue
- Collection of New Marine Microorganisms and Useful Natural Products from Marine-derived Microorganisms
- Anxiolytic-like Effects of Portulaca Oleracea Linne Using the Elevated Plus-maze Test in Mice.
- Development of Image-based Calcium Mobilization Assay in Single Cells Based on High Content Screening Technology
- Antioxidant Potential and Quantitative Analysis by Using LC/MS/MS with Rosmarinic Acid for Perilla Frutescens Extracts
- Bioactive Compounds Isolated from Stem Bark of a Vietnamese Medicinal Plant Gardnia oblongifolia(Clusiaceae)
- Influence of the Delivery Systems Using a Microneedle Array on the Permeation of a Hydrophilic Molecule, Calcein
- Isolation, Structure Elucidation, Antioxidant Evaluation with On-line HPLC-DPPH Method of Radical-Scavenging Hispidin Derivatives from Fruiting Body of Phellinus linteus
- Suppression of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Expression by l\issilagone from Farfarae Flos in BV-2 Microglial Cells
- Neuroprotective Effects of SP-8203 in Ischemic Brain Injury
- Hederacolchiside Al-induced Apoptosis in Immortalized Keratinocytes
- Polymeric Nanoparticles with Anticancer and Contrast Imaging for Liver Cancer
- Redox Signaling of G Protein-coupled Receptors
- Regulation of Innate Immunity for Host-Bacteria Symbiosis
- Citrus Grandis Osbeck Leaves Inhibit the Production of NO and IL- 6 by Down Regulationg JNK Activity in LPS-Stimulated RAW 264.7 Cells.
- Actin Cytoskeleton is Responsible for Src Kinase Activation
- cDNA Cloning and Expression of Spatzle Processing Enzyme(SPE) Involved in Lysine-iype Peptidoglycan Recognition Signaling Pathway in Tenebrio Molitor Larvae
- Relationship between Epigenetic Modifications and Activity/Safety of Embryonic Stem cells
- Comparative Analysis of Proteome Profiles of Helicobacter pylori 26695 Cultured under Aerobic and Microaerobic Conditions
- Evaluation of in vitro Stability of Natural and Modified Enkephalins
- Pharmacokinetic Characteristics of Intranasal Levodopa and Carbidopa Form ulation in Rats
- In vitro Absorption and Metabolism Characteristics of 2'-Benzoyloxycinnamaldehyde, an Antitum or Drug Candidate
- Determination of MirodenaHi, and Its Metabolites, SK3541 and SK3544, in Rat Plasma, Urine, and Various Tissue Homogenates by High-performance Liquid Chromatography
- Purification and Physiological Function of a Lectin from Macrophthalmus japonicus
- Preparation and Evaluation of Novel Cationic Solid Lipid Nanoparticles for the Delivery of p53 gene into Lung Cancer Cells
- Effect of Rifampicin on the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone in Rats
- Validation of Analytical Procedures
- Drug Product Quality Assessment and Global Regulatory Harmonization
- Development of Novel A3 Adenosine Receptor Antagonists
- Modulation of P-Glycoprotein-mediated Transport by Naturally Occurring Compounds
- Role of Transporters on Pathophysiological Aspect of the Blood-Placenta Barrier
- Gastroprotective Effect of QGC on Indomethacin-lnduced Gastritis in Rats
- Anti-inflammatory Activity of (Z )-Ligustilide and Senkyunolide A via Inhibition of NF -kB Pathway
- Manassantin A Inhibits Maturation and Immune Functions of Bone Marrow-Derived Dendritic Cells
- Transient Global Ischemia Induces Morphological Changes in the Hippocampal CAl Region and Memory Impairments in Mice
- Regulation of Soluble Amyloid Precursor Protein Alpha and Cell Viability by Amyloid Beta in SH-SY5Y Cells
- Correlations between Quantitative EEG Cordance Evoked by Music Listening and Personality Traits
- Prevention of P-cell Destruction and Inhibitory Roles of Laccase in the Process of p-cell Damage by Its Radical Scavenging Property
- GCC1290, a New Oral Drug Candidate for the Treatment of Parkinson's disease
- Cytotoxic and Anticomplementary Components from Herbal Medicines
- Orphan Nuclear Receptor Nur77 Is Acetylated by p300
- Ursodeoxycholic Acid Decreases Expression of Inflammatory Factors and Co-stimulatory Molecules via Inhibition of NF-kB and STAT I Pathway in RAW264.7 Macrophages
- Characterization of Viable but Nonculturable Condition of Escherichia coli Induced with Copper
- Induction of Differentiation of Human Promyelocytic Leukemia HL-60 Cells by Nargenicin
- Anti-Colon Cancer Effects of Fucoidan Isolated from Fucus vesiculosus
- The Role of LXR in the HBx-induced Hepatic Lipogenesis
- Design and Synthesis of Guanidine Derivatives toward Development of iNOS Inhibitors
- Growth Inhibition and Induction of Autophagy by Yuanhuadine in Human Lung Cancer Cells
- 1624 G>C single Nucleotide Polymorphism in 3'-untranslated Region Influences the Expression of SUV39H2 Histone Methyltransferase
- Enhancement of the Anti-Proliferative Effects on Human Colon Cancer Cell Lines by Bifidobacterium adolescentis SPM0212 Extract
- Synthesis and Anti-inflammatory activity of [I-3',II-7]biflavone Analogs
- Purification of Snail-importin β Protein Complex
- Rapid and Sensitive Determination of Acyclovir in Hum an Plasma by HPLC/UV
- Synthesis and Biological Evaluation of Pregnane Derivatives as 5α-Reductase Inhibitor
- Determination of an Agent for the Inflammatory Liver Disease, Liquiritigenin, in Rat Plasma, Urine, and Various Tissue Homogenates by High-performance Liquid Chromatography
- Cytotoxic Components of Picrasma Quassioides
- Analysis on Perception of Price Managers in Pharmaceutical Companies on Positive List System in Korea
- Anti-Stress Effect of Lactic Acid Bacteria in ICR Mice
- Antiproliferative Effect of Fermented Ginseng, BST-204, on HT-29 Human Colon Cancer Cell
- Comparative Changes in the Metabolomics of Sulfur-Containing Substances in Liver of Rats TVeated with L-Buthionine-(S,R)-Sulfoximine (BSO) and Phorone (PHO)
- Blockade of Atopic Dermatitis-Like Skin Lesions by DA -9102, a Natural Medicine Isolated from Actinidia arguta, in the Mg-deficiency Induced Dermatitis Model of Hairless Rats
- Combinatory Mechanisms of TetraA s？？ in Combination with Cytotoxic Anti-cancer Agents against Human Cancer Cells
- Bioactive Constituents from Marine Organisms Inhabiting in Vietnamese Sea
- Regulation of Ceramide-induced p27kip1 Expression by PP2A Activation in PC-3 Prostate Cancer Cells.
- ERK 1/2 Signaling Pathway is Involved in Verproside-Mediated Anti-inflammation in a Mouse Model of Allergic Asthma
- Methylmercury Content of Animal-origin Natural Medicine Determined by Gas Chromatography Electron Capture Detection
- Effect of Xanthohumol on Chronic Oxazolone Induced Dermatitis in Mouse
- The Effect of Natural Products on Collagen Biosynthesis
- The Naturally Occurring Flavolignan, Deoxypodophyllotoxin, Inhibits Lipopolysaccharide-induced iNOS Expression Require Inhibition of NF-kB Activation in RAW264.7 Macrophage Cells
- Pharmaceutical Promotion, Prior Authorization and the Use of Erectile Dysfunction Medications in the Medicaid Population
- Differential Proteomic Analysis of Kidney Toxicity Induced by Cisplatin
- Free-radical Scavenging Activity of Gentiana scabra var. buergeri
- Antiinflammatory Activity of Angelica Dahurica and Rapid Identification of Active Constituent by LC-NMR/MS
- Quality Diagnosis of National Statistics in Healthcare
- Metallothionein-III Protects against 6 -Hydroxydopamine-induced Oxidative Stress by Increasing Expression of Heme Oxygenase-1 in a PI3K and ERK/Nrf2-Dependent Manner
- Nanocrystalline-Silver Impregnated Activated Carbon Matrix with High Activity Antibacterial
- The Association of Internet Addiction with Excessive Daytime Sleepiness in Korean Adolescents
- Determination of Norfloxacin in Human Plasma by High Performance Liquid Chromatography with Fluorescence Detectio
- Electrochemiluninesce-based DNA Detection Using Microelectrode Array
- Construction of Knowledge Based Drug-disease Contraindication Database for Drugs Approved in Korea
- Factors Related to Weight and Album in Affecting Neuropenia in Korea Solid Cancer Patients
- Total Synthesis of (-)-Macrosphelide K
- Evidence of P-glycoprotein (P-gp) Expression In Human Nasal Epithelial (HNE) Cell Monolayers Cultured by Air-liquid Interface (ALI) Method
- Electronically Modified Polymer-Supported Cinchona Phase-lVansfer Catalysts for Asymmetric Synthesis of α-Alkyl-a-Amino Acid Derivatives
- 3-Hydroxymorphinan, the Parent Molecule of GCC1290, Provides Neuroprotection against Glutamateinduced Toxicity
- Protein lyrosine Phosphatase IB Inhibitory Activity of Antimycins Isolated from Actinomycete AN070088
- New Approach to Chiral Oxazolidin-2-one from Oxirane with Use of Chlorosulfonyl Isocyanate and Its A pplication to the Synthesis o f a -(-)-conhydrine
- Inhibitory Effect of THphlorethol-A on MMP-1 Induced by the Oxidative Stress in Human Keratinocytes via ERK and AP-1
- Constituents from the Vines of Lonicera Japonica
- Pyrroloiminoquinones Isolated from a Deep-Water Alaskan Sponge of the Genus Latrunculia
- Total Synthesis of Fhivirucinine Bl
- Characterization of Recombinant a-GIucosidase of Bifidobacterium H-1
- Protective Effect of Nelumbo Nucifera on a Radiation-induced Oxidative Damage in a RAW 264.7 Macrophages Cell and a Quantitative Analysis with Isoquercitrin
- Simultaneous Determination of Flavonoids from Extracts of Nelumbo nucifera Leaves by High-performance Liquid Chromatography
- Genomic Analysis of Statin Treated Rat Skeletal Muscle Cells
- Preparation and Characterization of PLGA Microspheres Containing PEGylated Exendin-4
- Identification of Diarylheptanoid Derivatives from Alnus Hirsuta
- The Standard Protocols for Bioequivalence Test
- Synthesis of Quinazoline Derivatives as Protein Kinase Inhibitors
- Protective Role of Sulfiredoxin in Apoptosis under Oxidative Stress
- Simultaneous Determination of Paeoniflorin,trans-cinnamic acid, Schisandrin and Glycyrrhizin in So-Cheong-Ryong-Tang by HPLC-DAD and HPLC-ESI-MS
- Patent Linkage System in Korea
- Effects of a Novel Propofol Microemulsion on Microbial Growth
- Absorption, Metabolism, Distribution, and Excretion of [14C]BR-A-657 Following Oral or Intravenous Administration to Rats
- 3D QSAR Studies of CK2 Inhibitors Using CoMFA and CoMSIA
- Re-Activation of Insulin Signaling by Adiponectin in Insulin-resistant Cells
- Improvement of Memory Impairment by Ltheanine through its Anti-oxidant and Neuroprotective Effect
- Involvement of the Nrf2 -antioxidant System in Chemoresistance of Cancer Cells
- Protective Effect of Fermented Ginseng (FG) and Cortex cinamomi Extract on Streptozotocin-induced Damage in Rat Pancreas β-cell
- Quantitative Targeted Proteomics as a New Strategy for the Blood-Brain Barrier Research
- Transcriptomic Analysis in the High and Low-Dose Epigallocatechin-3-gallate and Propyl Gallate-treated HepG2 Cells
- Effect of Hinokitiol, a Tropolone Derivative, on TNF-α Production in LPS-activated Macrophages
- Cloning of the Novel Glycoprotein DNA from Erimacrus Isenbeckii
- Involvement of Matrix Metalloproteinase-9 (MMP-9) in ATP-induced Microglial Migration
- Preparation and Characterization of Solid Dispersion of Coenzyme QIO
- Novel Hyaluronan Nanoparticles for Tumor Targeting
- Antioxidant Activities of Different Extracts from Aralia elata Seeds
- Current Status and Future Prospect of Chuncheon Biocluster
- Corynoxeine Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation through the Inhibition of ERKl/2 Activation
- Effects of Tanshinone IIA on the Hepatotoxicity and Gene Expression Involved in Alcoholic Liver Disease
- Separation of Ceramide 1 -Phosphate by Hexane-Ethanol Extraction and Quantification by High Performance Liquid Chromatography
- The Expression of Kainate Receptors and Microtubule-Associated Protein 2 in the Hippocampus of Maternal Separation Rat Pups
- Calorie Restriction Modulates Visceral Lipid Accumulation and Inflammation in Ob/ob Mice
- A Chemoselective Deprotection of Bulky IVialkylsilyl Acetylene by Silver Fluoride
- Anti-proliferative Activities of Benzamide Derivatives
- study on the Risk Assessm ent of the Menstrual Pads and Tampons
- lontophoretic Delivery of Donepezil hydrochloride
- Cimiside E, a Potential Antitumor Natural Product, Induces Cell A poptosis via Fas Sign aling Pathway
- Pharmacokinetic Parameters of Oltipraz in Liver Cirrhotic Rats with Diabetic Mellitus
- Role and Relevance of Membrane Transporters in Pharmacokinetics, Pharmacological Activity, Toxicity and Diseases
- Screening for SNPs and Haplotypes of CYP1A2 Gene in a Healthy Korean Population
- An Analytical Method to Quantify Phytoceramides by High Performance Liquid Chromatography after SCDase Release of Sphingoid Base
- New Isolate of Streptomyces olivochromogenes Producing Extracellular Proteases.
- Isolation, Identification and Quantification of Anti-Oxidative Compounds from Diospyros kaki calyces
- Glycyrol, an Acyl-coenzyme A: Cholesterol Acyltransferase Inhibitor from Licorice Roots
- HlF-l Inhibitors from Morus Species
- Protection of Kainate Neurotoxicity by Ginsenosides: Attenuations in the Convulsive Behaviour, Mitochondrial Dysfunction and Oxidative Stress
- Progress for Standardization of Traditional Medicine, Angelica tenuissima by Isolation and Various Analysis Techniques
- Doxorubicin Nano-micelles Targeted for Epidermal Growth Factor Receptor Overexpressing Tumor Cells
- The Meianogenesis Inhibitory Effect on B16F10 by Periostracum cicadae
- Inhibitory Effects of Stress Factors by Oligonol Supplementation in the Male Subjects
- Clean, Safe, Secure and Efficient Cleanroom Engineering in Pharmaceutical Production
- The Pharmacokinetics of Gabapentin, Levosulpiride, and Risperidone According to the Genetic Polymorphisms of M DRl Gene
- In silico Study of Aurora Kinase Inhibitors Using 3D QSAR and Molecular
- Effect of Administration Routes on the Mucosal and Systemic Immune Responses against Subunit Vaccine in Mice
- Acquired Butyrate Resistance in Human HCT116 Colon Cancer Cells Induces Resistane to Other Anti-cancer Drugs
- Optimization of the Generation Methods for Cytokine-lnduced Killer Cells from Mouse Spleen Cells
- ATR, a S-Phase Checkpoint Kinase Upregulates Chromatin Binding of Cdc6 in Synchronized HeLa Cells
- Meteorin Regulates Neuro-Glial Fate Decision through Induction of BMPs
- The Modulatory Effects of Paeonia Suffruticosa Andrews on the LPS-induced Activation of BV2 Microglial Cells
- The Effect of Siegesbeckia Glabrescens Makino in Nitric Oxide Production on Human Umbilical Vein Endothelial Cells
- Crystal Structure of C12H14O3N2S3
- Quantitative Analysis of Rabeprazole in Human Plasma by LC-MS/MS Using Rapid and Simple Sample Preparation
- Lectin from the Mushroom Cordyceps militaris
- Chungsim-Yeunja-Tang Inhibits the LPS -induced IL-32 Production via Inhibition of NF-kB and Caspase-1 Activation in Peripheral Blood Mononuclear Cells
- The Development of the Doctor of Pharmacy Program in the United States
- Potential Anticancer Agents from Marine Invertebrates
- Discovery and Early Development of SKL11197,a Novel Neuropathic Pain Drug
- Role of the Nrf2 Pathway in Cell Survival
- Distribution of Polymethoxyflavonoid Contents in Jeju Native Citrus Plants and their Physiological Activities
- Analyzing on the Functional Material Studies in Jeju Citrus Industry
- Anti-ulcer Activity of Hydnocarpi Semen Extract on a Traum atic Wound in Streptozotocin Induced Diabetic Mice.
- Synergistic Decrease in Blood Pressure of Candesartan Combined with Lacidipine in Spontaneous Hypertensive Rats
- Anti-inflammatory Effects of Extracts from Jeju Dangyuja(Citrus grandis Osbeck)
- Protective Effects of Citrus Pectin against TCDD Toxicity
- A High-Yield Approach to the Selective Synthesis of D-arabino-, D-lyxo-, and D-xy/o-Phytosphingosiiies from Inexpensive D-ribo-Phytosphingosine
- Tyrosinase Inhibition Study of Bromophenoxyphenylether Analogues
- Analysis of Ginsenoside Composition of Ginseng Flos
- Simultaneous Analysis of Parabens in Cosmetics
- Development of Quantitation Analysis Method of Bamboo Leaf Using Alternative Standards
- Real Time Analysis o f Dihydro-A2E: An Intermediate in the A2E Biosynthesis
- Immune-enhancing effect of Drynariae Rhizoma(DR)
- Efficient Delivery of siRNA Using Hyaluronic acid and Polyethyleneimine Derivatives
- Carbphydrate Analysis on the Glycoproteins Using High-performance Anion-exchange Chromatography with a Pulsed Amperometric Detection
- Studies on the Preparation of Nanoemulsion of a Newly Synthesized Quinazoline for Developing as Skin Whitening Agent
- The Effect of Dibucaine-HCI on Rotational Mobility of n-(9-Anthroyloxy)stearic Acid in Neuronal and Model Membranes
- Measuring Utility Weights for Severe Stomach Cancer
- Oral Exposure to Mercuric Sulfide Alters T Lymphocyte Phenotypes in Mice
- Environmental Toxic Metabolites and Structure Relationship in CNS Neurotoxicity
- Effect of Cotreatment of Pidotimod and Red Ginseng Acidic Polysaccharides on Peritoneal Macrophage Function in Immunosuppressed Mice
- Efficient Method to Enrich Phosphopeptides and Map the Phosphorylation Sites in Phosphoproteins Using Proteomics Technology
- Protective Effect of Caffeic Acid Phenethyl Ester against Carbon Tetrachloride-induced Hepatotoxicity in Mice
- Curry Curcumin Inhibits Mast cell-mediated Allergic Response at the Level of Syk Kinase
- Analysis of KCNEl genes for the SNPs in Korean Genome
- Manassantin A Inhibits cAMP-dependent Melanin Production in Melanoma B16 Cells
- Silencing of Tumor Suppressor RUNX3 by Histone Modification in Hypoxic state Stimulates Angiogenesis in Gastric Cancer
- Induction of Apoptosis by Sulforaphane Analogues in Human Colon Cancer Cells
- Targeting the Ras Oncoprotein for Anti-cancer Drug Discovery and Treatment
- Pharmaceutical Patent Strategy from Litigation Cases
- Mass Spectrometry Based Metabolomic Approach for Biomarker Discovery
- Achiral and Chiral Separation of Chiral Acids, Amines and Amino Acids by Gas Chromatography and Capillary Electrophoresis
- Asymmetric Synthesis of Aminocyclitols as New Glycosidase Inhibitors
- Combined Treatment with Coenzyme QIO and Statin in Hyperlipidemic Rats.
- Analysis of Gliclazide and Nabumetone Related Compounds with HPLC
- Anxiolytic-like Effects of Sanjoinine A Isolated from Zizyphi spinosi Semen
- Anti-inflammatory Activities of Panax ginseng Head BuOH Fraction in Mice
- Eupatilin Protects Gastric Epithelial Cells from Oxidative Damage and Down-regulates Genes Responsible for the Cellular Oxidative Stress.
- Contents of Heavy Metals in Commercial Herbal Medicines in Seoul (2007)
- Synthesis of Benzo[b|oxepine Derivatives, Constrained Form of 3-ArylisoquinoUnes, as Potential Antitumor Agents
- Identification of Genes Differentially Expressed in the MCF-7 Cells Treated with Mitogenic Estrogens
- Isolation of Chemical Constituents from Polyporus
- Anti-inflammatory Effect and HPLC Analysis of Extract from Edible Cirsium setidens Nakai and Its Isolated Compound
- Comparison of the Effects of Bile Components and Total Bile Acids on Cell Viability
- Study on Sell-by-Date of Health Functional Foods;UniBEX™ and Univestin-K
- Parallel Applications of Integrated Circuit Bipolar Semiconductor Microchip as a Miniaturized Sample Platform and a Two-dimensional Photodetector for Optical Detection of Biomolecules
- Protective Effect of glycyrrhiza inflata against High Glucose-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells
- The Estrogenic and Antiestrogenic Action of Epimedii herba in Ovariectomized Rats
- Development and Validation of a LC-MS/MS Method for Determination of Goserelin in Rat Plasma
- P54nrb is a Key Regulator of Tijmor Cell Invasion
- Determination of lndirubin-5-nitro-3'-monoxime in Rat Plasma by Liquid Chrom atography/Electrostray Ionization Tandem Mass Spectrometry
- Target Specific Intracellular Delivery of siRNA/PEI-HA Polyplex
- Strategies for Preserving the Solubility and Activity of T\imor Necrosis Factor-related Apoptosis Ligand Following Freeze-Drying
- Three-layered Tablet with Poly(Ethylene Oxide) Core M atrix Capped by Carbopol: Solid State Characterization and Dissolution
- Pharmacokinetic Characteristics of lontophoretic Levodopa and Carbidopa Formulation in Rats
- Block Inomer Complexes as Prospective Nanocarriers Nanocarriers for Drug Delivery
- Preparation and Evaluation of Solid Lipid Nanoparticles Using a Newly Synthesized Quinazoline
- Cationic Liposome-mediated Delivery of Therapeutic Genes
- Dioleoyiphosphatidic Acid Induces Morphologic Change in an Endogenous LPA Receptor-dependent Manner in C6 Glioma Cells
- Genetic Toxicity Test of Tetrachloroethylene by Ames, Micronucleus, Comet Assays and Microarray Analysis.
- Screening of Small Molecule Inhibitors of XIAP/Caspase-3 Interaction Using Protein Chip (Cl-chipver1.0)
- The G12 Family Proteins Upregulate MMP-2 Leading to Human Breast Cell Invasion
- Identification of Differentially Expressed Genes in Mouse During Hypoxia Using Annealing Control Primer System
- Isolation and Biochemical Characterization of Bioactive Lysine-iype Peptidoglycan Fragments from Staphylococcus aureus Cell Wall Components
- Syk is Responsible Kinase for Regulating Early Phosphorylation of IkBα
- Molecular Cloning and Heterologous Expression of Novel Channel-like Protein, TMEM16D
- Development of in vitro Toxicity Methods, which Alternate in vivo Assay at an Early Stage of Drug Discovery
- Physiological Functions of Src-Family Kinase Isoforms,Lyn, Fyn, Fgr, and c-Src on Degranulation in Mast Cells
- Novel Quinazoline JSH-18 Inhibits Melanin Production in B16 Melanoma Cells
- Inhibitory Effect of Chalcone JSH-1144 on Interleukin-3-dependent Proliferation of Pro-B BaF/B03 Cells
- Eckol Protects V79-4 Cells Against G-Ray Radiation-Induced Apoptosis via the Scavenging of Reactive Oxygen Species and Inhibiting of the C-Jun NH₂-Terminal Kinase Pathway
- The Change of Ginsenoside Composition in Ginseng Extract by The Ascorbic Acid Process
- Isolation of Compounds from Cnidii Fructus
- Lipopolysaccharide Modulates Tissue Plasminogen Activity through the Regulation of Plasminogen Activator lnhibitor-1 in Rat Astrocyte
- In Vitro Anti-inflammatory Activity of 3-0-methyl-flavones Isolated from Siegesbeckia Glabrescens
- Non-viral Gene Therapy Carrier Employing Poly (ethylene imine)-poly(ethylene glycol) grafted Chitosan
- First Asymmetric Synthesis of Optically Active H₁Receptor Antagonist Clemastine
- Antioxidant Compounds from Ilex cornuta L.
- Synthesis and Antioxidant Activity of 3,4,5-TVihydroxy-N-(2-hydn)xyphen}iethyI)benzainides(TH-HPEBA)
- Vascular Smooth Muscle Dysfunction Induced by Ginsenoside Rg3, a Bioactive Component of Ginseng
- Development of Atopic Dermatitis-Like Skin Lesion with Dermatophagoides Farinae Extracts in Immune-imbalanced BALB/c Mice
- Discovery of Novel Nuclear Factor (NF)-kB Inhibitors Using Chroman Carboxamide Derivatives
- Approaches Needed for Toxicity Testing of Nanoparticles
- Development of CG100649, a Next Generation NSAID
- Studies on the Preventive Effects of Fruit of Broussonetia papyrifera(L.) Vent on Osteoporosis.
- Application of Toxicogenomic Technology for the Improvement of Risk Assessment
- Protective Effects of the Water Extracts of Hovenia Dulcis Thunb against Ethanol-induced Toxicity in Primary Cultured Rat Hepatocytes
- In hibition of Transforming Growth Factor-β1 induced Hepatic Fibrosis by Gα12 / Gα13 Deficiency
- First Synthesis and Unusual Conformation of 4"-Selenonucleosides
- Review on the Clinical Pharmacy Education in the U.S.A.
- Current Situation and Issues on the Pharmacist in Japan
- Statistical Analysis and Safe Use of Drug Following by Adverse Drug Reaction
- Analysis of Polypharmacy and Related Factors
- Sialylated Oligosaccharide Analysis on the Glycoproteins Using a High-performance Liquid Chromatography with a Fluorescence Detection
- Determination of Aceclofenac in Human Plasma by HPLC/UV
- Analysis of Prescriptions for the Elderly at Primary Health Care Using National Health Insurance Database
- Review : Characteristics of Various Pharmacokinetic/Pharmacodynamic Models
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