학술논문
Mechanisms of apoptotic induction and cell cycle inhibition by novel compounds obtained using analogue synthesis and structure-based durg design in cancer cells
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- Kim Min-Kyoung Chae Jin A Kang Jeong Hwa Oh Ha Lim Cho Youl-Hee Kim Hak Yeop Koo Bon Am Lee Chul-Hoon
- 간행물 정보
- 『춘계총회 및 학술대회』(2005년) vol.1, 258~258쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2005.04.30
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해당간행물 수록 논문
- Hypoxia Induces ES Cell Di^erentiation by Negative Regulation of LIF-Stat3 Pathway
- Mechanisms of apoptotic induction and cell cycle inhibition by novel compounds obtained using analogue synthesis and structure-based durg design in cancer cells
- Sensitive Determination of Fluvastatin in Rat Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry
- Positively charged colloidal nanogold particle-based gene delivery
- PI3K and pERK mediates the survival of TCDD-treated SK-N-SH human neuronal cells
- Effect of Dextromethorphan on the immunopathological parameters and serum immunoglobulin in mice.
- Estabilishment of the specifications on herbal medicines - Physiochemical quality evaluation of the herbal medicines
- Synthesis and antiviral evaluation of novel acyclic nucleotide analogues
- Current Issues of Pharmaceutical Equivalence
- Protective Roles of Gadd45a in response to alkylating agents
- Synthesis of substituted pyrrolopyridothiazocine derivatives
- Sesquiterpene Glycosides from the BuOH fraction of Saussurea pulchella Fisch
- Salicornia Herbacea protects against oxidative stress induced by ovariectomy
- Anticancer Effect of Isoimperatorin from Angelica koreana
- Study on the toxicity of heavy metals and the protective effects of food components in cells with hormone receptors
- Improvement of lipid profiles and anti-diabetes effects of Cinnamon and Rhodiola rosea in db/db mice
- p-Secretase (BACEl) inhibitors from Sanguisorbae Radix
- Phenylethanoid Glycosides From Callicarpa dichotomy Protect Cultured Rat Cortical Cells From Glutamate-Induced Neurotoxicity
- Anxiolytic-like effects of Polygala tenuifolia Willdenow using the elevated plus maze and hole-board apparatus in mice
- Potent inhibition of the induction of nitric oxide synthase by chrysoeriol
- Diagnostic detection of 14 mycoplasma species by two-stage nested PCR
- Preclinical Evaluation of the Radioprotective Effect of Caffeine in Whole-body g-Irradiated Testes
- Regulatory Aspects of Cell Therapy Products
- Anti-hypertensive effect and related mechanisms of Korean mistletoe extract
- A Facile Synthesis for Asymmetric Dimers of N-Alkylated 2,3-Dihydro-2-phenylquinolones
- High Throughput Systems for Peptide Synthesis & Protein Identification
- Effect of Leucocyanidine and herbal extracts on the levels of lipid profiles in ethanol-fed rats
- SB-Injection, an anticancer agent prepared from the roots of
- Clinical Evaluation of Biologies
- Binding model of Tripeptide based of FTase Inhibitors
- JNK Down Regulate The Expression of Antimicrobial Peptide Genes
- Acute toxicity of chlorostyrenes to Caenorhabditis elegans
- Determination of ranitidine in human plasma by high-turbulent liquid chromatography with ultraviolet detection
- Effect of pneumococcal stress gene adh on gene expression and cytokine release in the host
- Sensitive determination of pinaverium in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry
- Upregulatory Effect of NMU and NEU on Cellular NF-kappaB Activity in Human Keratinocytes and Murine Macrophages via Protein Kinase C Inhibition
- Regulation of Phospholipase D and Secretion in Mast Cells by Protein Kinase A and Other Protein Kinases
- General Pharmacology of DA-9102, the Therapeutics of Atopic Dermatitis Derived from Herbal Medicine
- Pharmacokinetic-pharmacodynamic modeling for the glucose lowering effects of glimepiride in healthy humans
- Metallothionein-111 induces heme oxygenase-1 in human neuroblastoma SH-SY5Y cells
- Synthesis, Topoisomerase I and II Inhibition and Antitumor cytotoxicity of terpyridine derivatives
- Synthesis of Terpyridine Derivatives Containing Thiophene at 2, 6- Position and Evaluated their Antitumor Activities
- Protection of LLC-PKl cells against hydrogen peroxide-induced cell death by modulation of ceramide level
- C-Reactive Protein Induces Apoptosis in Human Monocytic Leukemia Cells
- Antidandruff effect of Resina Pini
- The quantitative analysis of asymmetric dimethylarginine, endogenous nitric oxide synthase inhibitor in biological samples
- Prediction of Mutagenicity of Structually Diverse Compounds Using Rprop Neural Net Method
- CV Safety & Future Generation COX-2 inhibitors
- Novel T\imor-Suppressing Signal Pathways: A Window for Target-Specific Anti-Cancer Drug Development
- Validation of Cell Substrate
- Effects of Di(n-butyl)phthalate on Gene Expression of the Male and Female Reproductive Organs
- Induction of 4-nitroquinoline 1-oxide phase II drug-metabolizing enzyme by isoflavonoids isolated from Pueraria Radix
- Medication Counseling to Patient on DUR Focusing NSAIDs,CVS Drugs, Anti-hyperlipidemias and Diuretics
- Qualitative analysis of phase I metabolites of tryptanthrin in vitro by liquid chromatography/electrospray ionization-tandem mass spectrometry
- Metabolism of Ebastine in Healthy Subjects with CYP2J2 Heterozygous Mutation
- Regulatory Prospective on Quality Evaluation of Pharmaceuticals
- Analysis of drugs in Human Postmortem Bone
- Establishment of Cisplatin-Resistant Gastric Carcinoma Cell Line and Examination of Apoptotic Gene Expression Change
- Synthesis of Benzene/Tetrahydroquinoline linked-TZD Analogs as Novel Activators of PPARy
- Asymmetric Synthesis of (+)-FlutriafoI
- ErbB2 expression in p53-inactivated mammary epitheilial cells
- Downregulation of phagocytosis in the presentation of exogenous particulate antigen association with Class I Major Histocompatibility by WP and CP in murine dendritic cell
- Structural Chemoproteomics for Drug Discovery at the Post-Genomic Era
- Proteomic Approach for Discovering The Drug Targets and Biomarkers of Diseases
- Study on Action Mode of Sphingosine-1- Phosphate in Rat Hepatocytes
- Inhibitory Effect of Obovatol, a Biphenoic Component of Magnoia Obovata, on Rat Aortic Vascular Smooth Muscle Cell Growth
- TGF-p-Induced Upregulation of MMP-2 and MMP-9 Depends on p38 MAPK Pathway in Breast Epithelial Cells
- Differential expression of protease-activated receptors in patients with irritable bowel syndrome
- Effect of Fucoidan from Sea Cucumber Stichopus Japonicus in Ovariectomized Rats
- Targeting Signaling Pathways of Ischemic Brain Injury
- Anti-obesity effects of EASA(Extract of Aster Spathulifolius Aerial Part) in high fat diet induced obese rats
- DNA damage in plasmid DNA treated with boron compounds, H2O2 and cysteine after gamma irradiation
- DW1350, a Newly Synthetic Anti-osteoporotic A gent: 5. Effect of DW-1350 in Rib Fracture Rat Model, a Histomorphometrical Aspect.
- Stress-induced Reinstatement of Cocaine Seeking: Non-human
- Pharmacokinetic Modeling of the Drug Metabolism using Primary Cultures and Cryopreserved Hepatocytes
- The Effects of Morin on the Pharmacokinetics of Diltiazem and Its Major Metabolite, desacetyldiltiazem in Rats
- 3D-QSAR Comparative Molecular Field Analysis on Morphorine Substituted Quinazoline Derivatives as RTK Inhibitors
- Principles for Theoretical and Methodological Issues in Behavioral Analysis
- Importance of Metabolism to Risk Evaluation of Environmental Chemicals
- Cognitive Aging, Stress and Pharmacological Intervention
- Protective effects of 3-caffeoyl-4-dihydrocaffeoyl quinic acid isolated from Salicornia herbacea on the acetaldehyde-induced activation of hepatic stellate cells
- Evaluation of immunomodulating activities of various calf thymus samples on human Jurkat T cells
- Preparation And Evaluation Of Chitosan-w/o/w Multiple Emulsion For Oral Delivery OfLMWH
- Subacute Oral Toxicity of natural Phellinus linteus in Sprague-Dawley Rats
- Antinociceptive Antiinflammatory Effect of Siegeskaurolic Acid A Isolated from Siegesbeckia pubescens
- Determination of losartan in human plasma using high-performance liquid chromatography with fluorescence detection
- Effect of Silibinin on Rat Vascular Smooth Muscle Cell Proliferation and Intracellular Signal Transduction Pathway
- Evaluation and Improvement of Bioavailability of YH5531, a New Hepatitis C Virus NS3 Protease Inhibitor in Rats by Prodrug Approach
- Relationship between genetic polymorphism of cytochrome P450 2C19 and gastic cancer
- Synthesis and Biological Activity of Geranyloxy Compounds
- Amomi Semen decreases immediated-type allergic reactions and cytokine production
- Effects of CYP2C9 polymorphisms on pharmacokinetics of losartan in healthy Korean subjects
- Bioequivalence of Surfolase™ Capsule to Acephyll™ Capsule (Acebrophylline100 mg)
- Chlorocinnamaldehyde inhibits NF-kB-dependent TNF-alpha expression in LPSstimulated macrophages
- Study on the metabolic properties of metoprolol by CYP2D6 genotype in Korean
- B road -spectrum antioxidant peptides derived from His residue-containing sequences present in human paraoxonasel
- Analysis of Amphetamines in Rat urines by automatic solid phase extraction
- Dual role of tumor necrosis factor a in the dependence and neurotoxicity induced by dextromethorphan
- Roles of Rac-MKK3/6-p38 pathway in H-ras-specific induction of invasion and migration of breast epithelial cells
- Wogon
- Cytotoxic Activity of Flavonoids from Cephalotaxus koreana Nakai
- Enhanced Predictive Tool for ADME properties : PreADME program
- Erythropoietin promotes cell proliferation: role of transcription factors.
- Stress related activities of Ginsenosides in SD Rats and ICR Mice
- Effects of DA-9102 on Atopic Dermatitis in NC/Nga mice
- Effects of natural product extracts on alcohol-induced fatty liver in rats and its action mechanism
- Betaine modulates NF-kB signaling pathway through enhancement of thiols
- Immunological effects of DNA vaccine against Hepatitis B Virus
- Design, Synthesis and Docking Study of 3'deoxyadenosine Derivatives as Human Adenosine Receptor Agonists
- Antiatopic Dermatitis action of Effective Compounds from DA-9102
- Pharmacognostical Studies on the Chinese Crude Drug 'Man Sam'
- Antioxidative Effect of Ulva lactuca Extract in Ovariectomized Rat
- Anti-Oxidative Phenolic Compounds from the Fruits of Actinidia arguta
- Quantitative Analysis of Pantoprazole in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry.
- Chitosan-mediated antisense oligonucleotides of LL-5 for the treatment of allergic rhinitis
- Determination of nicotine in human plasma by hydrophilic interaction liquid chromatography-tandem mass spectrometry
- Alteration of Electroosmosis Using PAMAM dendrimers
- Randomized, open-label, two-period crossover comparison of the pharmacokinetics and safety profiles of two amlodipine formulations in healthy adult male Korean subjects
- Determination of cilazapril in human plasma by liquid chromatographyelectrospray ionization tandem mass spectrometry
- The deadenilation of adenine-based nucleosides by the incubation of 2-bromopropane or other structurally related halogenated alkanes at the physiological condition
- The Mood Stabilizer Valproic Acid Protects the Brain from Hypoxic-ischemic Injury
- Inhibition of Inflammatory cytokines production by Scopoletin through blockade of NF-kB activation in human mast cell line HMC-1 cells
- Effects of dextromethorphan on the cytokine production and proliferation of mouse splenocytes in vitro
- Ascorbic Acid Ameliorates Hepatic Dysfunction Induced by Cold Ischemia/Reperfusion
- Dopamine Release in PC12 Cells Is Mediated by Ca고우-Dependent Production of Ceramide via Sphingomyelin Pathway
- CAPACITATIVE CALCIUM ENTRY IS INVOLVED IN REGULATION OF MUSCARINIC STIMULATION OF NF-kB MEDIATED sAPPa RELEASE
- Immunomodulatory effect of lectins from Korean mistletoe on macrophage functions
- Molecular identiflcation of medicinal mushrooms based on 25S rDNA sequences
- LC-NMR and LC-MS analysis of the protoberberine metabolites in Corydalis cell cultures
- Role of Monocarboxylic Acid Transporters in the Cellular Uptake of NSAIDs
- Bioequivalence of KJimain™ to Somalgen™(Talniflumate 370mg)
- Effect of Foeniulum Vulgare Essential Oil and Its Constituents on the Histamine Release from Mast Cells and Antioxidant Activity in vitro
- Effect of melanian snailon on non-alcoholic fatty liver disease in ob/ob mice
- Antioxidant activity of isoflayones from Amorpha fruticosa barks
- Phytochemical Constituents of Rosa multiflora
- Immunosuppressive effects of rutaecarpine in female BALB/c mice
- Cloning of Xenopus laevis TRPV2 by gene prediction
- Effect of aluminum on TNF-a secretion from murine RAW264.7 cells for endotoxin detection in hepatitis B vaccines
- Enhanced tamoxifen bioavailability after coadministration of tamoxifen with quercetin in rats
- Polyethylenimine-based antisense oligonucleotides of IL-4 suppress the production of IL-4 in a murine model of airway inflammation
- The effects of food on the bioavailability of fenoFibrate administered orally via sustained-release capsules in humans
- Astrocytes derived factors induce neurogenesis of neural stem cells
- Simultaneous determination of 6-gingerol, ginsenoside R gl, R b l, baicalin,berberine in the oriental medicines, i-jung-tang and ban-ha-sa-sim-tang, by HPLC analysis
- Pharmacokinetics of Amlodipine Enantiomers in Rats
- Reduced renal excretion of zalcitabine via the inhibition of organic anion transporters in the kidney
- Anti-Oxidative, Nitric Oxide and ProstaglandinEa Production Inhibitory Activities of Phenolic Compounds from the Seeds of Primus tomentosa Thunberg
- Novel g-Lactam base Histone Deacetylase (HDAC) Inhibitors
- Monitoring of Oriental Medicine (II)
- S promoted insulin resistance C57BL/6J mice
- In Vitro Inhibitory Activities of Essential Oils from Thymus magnus against Some Antibiotics Resistant Pathogens
- Metabolomics and Systems Biotechnology
- Astaxanthin and water extract from Vaccinium uiiginosum L. Decreased Wrinkle Formation
- Role of ceramide in NP-1 induced apoptosis
- Structural analysis of isoflavones and chalcones as IL-5 inhibitors
- Synthesis of New 3-AIIylthio-6-Aminopyridazine Derivatives
- Computational Screening of a Chemical Database to Find Novel Histone Deacetylase Inhibitor Leads
- Novel 9-membered Lactones from the Marine Sponge Topsentia sp.
- Licensure of Biotechnological Products in KFDA
- Therapeutic potential of d-lactam base HDAC inhibitors for Huntington's disease
- Establishment of HUVEC/C6 cell co-culture model of the blood-brain barrier drug transport
- Regulatory Aspects of Gene Therapy Products
- Antiplatelet Activity of Carnosol, a Phenolic Diterpene Component of Rosmarinus Offlcinials
- Gene Expression Patterns as Potential Molecular Biomarker for Formaldehyde Exposure
- Development of a high throughput screening amenable assay for melanin concentrating hormone receptor antagonists
- Bioequivalence evaluation of acebrophylline 100 mg capsule in healthy male Korean voluteers
- Simultaneous Determination of Five Anthracycline Antibiotics by High Performance Liquid Chromatography Coupled with Radial-Flow Electrochemical Cell
- Anti-oxidant Activity of Morinda citrifolia Extracts Is Enhanced by Treatment with HCl and Trypsin
- Systematic toxicological analysis procedure for drugs from unknown samples by HPLC(II)
- Signaling Events through CD40 in B Cell Activation and Maturation
- Activation of Neuroglia in the CNS Diseases
- Anti-inflammatory effects of natural products in alcoholic liver disease
- Molecular biomarkers of octachlorostyrene exposure in medaka, Oryzias latipes
- Inhibitory effect of melittin, a major component of bee venom, on FBS-induced proliferation of rat aortic vascular smooth muscle cells through inhibition of Akt and NF-kB activation
- Molecular and Cellular Basis for the Anti-tumor Activity of the HDAC inhibitor in Vitro and in Vivo
- The signaling mechanism on the sphingosylphosphorylcholine-induced contraction in cat esophageal smooth muscle cells
- Antiarrhythmic effects of KR-32570, a new potassium hydrogen exchanger inhibitor, on ischemia/reperfusion-induced arrhythmias
- Effect of ginsenosides Rg3(R), Rg3(S), Rgs/Rkj on learning and memory in the Ap(25-35) induced amnesia mice
- Study on the gene expression in the injured liver
- Anxiolytic-like effect of CBPharm-001 and its possible molecular mechanisms
- Neuroprotective Effect of Ginsenosides in Nitric Oxide-induced Apoptosis in Neurons
- Pharmacological actions of KKHA-761: a potent D3 receptor antagonist with high 5-HTia receptor affinity
- Comparison between high fat and high fat/ high carbohydrate diets
- Effect of NMDA receptor on analgesic effect of bovine milk-derived lactoferrin (BLF)
- Effect of Rhus verniciflua Strokes extracts on the human cytochrome P450 expression and catalytic activity
- Butein suppresses inducible nitric oxide synthase by means of an enhancement of avp3 integrin receptor in mouse macrophages
- Structure-activity relationship of dimethylsphingosine on intracellular pH and Ca in U937 monocytes
- Assay of Lipoprotein Lipase Activity in Rat Tissues
- Regulation of CYPIBI Promotor Activity In MCF-7 Human Breast Cancer Cells
- Ginseng total saponin inhibits morphine-induced up-regulation of cAMP pathway
- Comparison of analysis methods for detection of replication competent virus and functional titers of HIV-1 based Lentiviral vector
- Scopoietin induces activation of caspase-3 through the activation of c-jun Nterminal kinase in human leukemia cell line, HL-60 cells
- Differential Role of Mitogen-activated Protein Kinase Pathways in Oxidative Stress-induced Cell Death
- The responsiveness of platelet aggregation to catecholamines and other agonists
- Differential effects of promoters on duration of gene expression in hematopoietic and stromal progenitor cells
- Inhibitory effect of CBPharm-001 on inflammatory response in UVB-irradiated human flbroblast cells and lipopolysaccharide-induced Raw264.7 cells.
- Inhibitory effects of paeonol on the development of reverse tolerance to and psychological dependence on morphine in mice
- Decrease in DNA binding activities of NF-kB, AP-1 and SP-1 transcription factors in neuronal ceils expressing presenilin 2
- Cell therapy of diabetes mellitus: Effect of Heme Oxygenase-1 in PEGylated islets for improved immunoprotection and survival in vivo
- Clofibrate Reduces Age-induced Activation of Redox-Sensitive Transcription Factors, NF-kB and AP-1
- Inhibition of the cyclooxygenase-2 expression by ilekudinol B
- Phenylpropanoid glycosides from Achillea sibirica van discoidea
- The polymorphism of the MDRl gene in Korean population
- Effect of Angiotensin Converting Enzyme (ACE) Gene I/D Polymorphism on the Pharmacokinetic Parameters of Enaiapril Maleate
- TRANSIENT RECEPTOR POTENTIAL CANONICAL CHANNEL 1 (TRPCl) IS INVOLVED IN MUCARINIC RECEPTOR-MEDIATED sAPPa RELEASE
- PKC 8 dependent reactive oxygen species generation by lysophosphatidylcholine in Jurkat T
- The Effect of Dietary Flavonoids on the Benzo(k)fluoranthene-induced C Y PlA l Gene Expression
- Effects of Ovariectomy on Acetylcholinesterase Activity in Rats Treated with Pesticide Terbufos
- EFFECTS OF GREEN TEA EXTRACT (CUMS6335) ON CATECHOLAMINE RELEASE, VASCULAR CONTRACTILE RESPONSE IN THE SPONTANEOUS HYPERTENSIVE RATS
- Assessment of Estrogenic and Androgenic Activities of Cypermethrin by Uterotrophic and Hershberger Assays
- Inhibition of Antioxidant Gene Expression by Glucocorticoid Hormone : The Role of SMRT Mediated C/EBPp and Nrf2 Repression
- Inhibitory effect of CBPharm-001 on memory impairment and secretase activity in vivo
- Effects of Grape Seed Oil on Histamine Release from RBL 2H3 Cells and Free Radicals Generation in RAW 264.7 Cells
- The Expression of Gonadotropin-Releasing Hormone (GnRH) in the Hypothalamus of Experimental Autoimmune Encephalomyelitis-induced Mice
- Activation of p38 MAPK is involved in ET-l-stimulated COX-2 expression in Cultured Feline Esophagus Smooth Muscle Cells.
- In vitro immunosuppressive activities of recombinant CTLA4Ig from transgenic rice cells
- Hesperetin, a bioflavonoid, inhibits rat aortic vascular smooth muscle cells proliferation by arresting cell cycle
- Pharmacokinetics in ob/ob mouse and physicochemical parameters for DY-101357,a potent PPARs agonist
- Induction of heme oxygenase ameliorates hepatocellular damage induced by hepatic ischemia-reperfusion in rats
- Regulations of human XREM-CYP3A4 proximal promoter activities in HepG2 cells.
- Insulin-secretion activity of Euonymus alatus extracts in RIN-m5F cell line.
- Role of the Membrane NADPH Oxidase-Mediated Generation of Reactive Oxygen Species in the Apigenin-Induced Activation of K,Cl -Cotransport in Human Neuroblastoma Cells
- The Cytochrome P450 Catalyzed Drug Metabolism in Drug Development: Pharmacogenetics and Drug Interactions
- Epothilone B and D arrest cell growth via inhibition of NF-kB signaling pathway in SW620 human colon cancer cell
- Molecular modulation of ferulate on age-related changes in NF-kB and its gene expression
- Apicidin upregulates gelsolin to inhibit tumor cell motility
- Effects of 1 -Bromopropane on Hepatotoxicity in Male ICR Mice
- Toxicity of phenols to Caenorhabditis elegans
- Stereoselective Metabolism of Carbonyl Reduction of Eperisone In Vitro Metabolism
- Miniaturization of poly(ADP-ribose) polymerase assay for high throughput screening
- p-Secretase (BACEl)-inhibiting stilbenoids from Smilax Rhizoma
- Hemiterpenes of Ilex macropoda Miq.
- An Efficient Stereoselective Synthesis of (2S,3S)-3-Hydroxypipecolic Acid Using Chlorosulfonyl Isocyanate
- Two new flavonol glycosides from Luzula Capitata(Mig.)
- Effect of COX-2 inhibitor in anaphylactic and inflammatory murine model
- Anti-inflammatory and analgesic effect of methanol extract of Angelica dahurica and its fractions.
- INFLUENCE OF d-AMPHETAMINE ON CATECHOLAMINE SECRETION EVOKED BY NICOTINE, CYTISINE AND EPIBATIDINE
- Insulin-secretion activity of ginsenosides in RIN-m5F cell line.
- The Role of 5-HT3 Receptors in the Development and Expression of Behavioral Sensitization to Methamphetamine
- CAPACITATIVE CALCIUM ENTRY IS INVOLVED IN REGULATION OF MUSCARINIC STIMULATION OF NF-kB MEDIATED sAPPa RELEASE
- Topical application of low molecular weight heparin with surface-charged ultraflexible liposomes
- Induction of apoptosis in human oral epidermoid carcinoma cells by sophoraflavanone G from Sophora flavescens
- Characterization of rheological properties and phase behavior of micoroemulsion systems for transdermal delivery of aceclofenac
- Synthesis of licochalcone E
- Isolation of SSDl as a suppressor for a mutant of the kinetochore component SpclOS.
- Identification of phosphorylation site of mouse ARDl, a novel protein kinase C delta interacting protein
- The Mechanism of Anticancer Activity of ID-6105 on Ovarian Cancer Cell
- Tumoricidal activity of Sulfated Exopolysaccharide From The Marine Microalga Gyrodinium Impudicum (Strain KG03) In Macrophages.
- Point to Consider in Bioequivalence Evaluation
- Human Bronchial Epithelial Cell Monolayer By Air-Liquid Interface (Ali) Culture For Evaluation Of In Vitro Airway Drug Delivery
- Autotaxin-dependent uPA up-regulation requires PI3K/Akt/NF-kappaB pathways in human melanoma cells
- Effect of DW1350 on Chronic Inflammation: Formalin-Injection Hind Paw Chronic Inflammation Mice Model
- Analysis of Novel 6-Lactam base HDAC Inhibitors using QSAR
- Effects of diluted aloe, AHCC and PAHG on Gastric ulcer and Helicobacter pylori
- Quantification of Globotriaosylceramide in Biological Sample by Electrospray Ionization Tandem Mass Spectrometry
- Activation of MMP-2 and Induction of MTl-MMP by l^pe I Collagen in Human Breast Epithelial Cells
- Pharmacokinetics of Lithospermic Acid B Isolated from Salvia Miltiorrniza in Rats
- Identification of optimal molecular size of modifled Aloe polysaccharides with maximum immunomodulatory activity
- Determination of Fexofenadine in Human Plasma by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry
- Selectivity between Bacterial DNA Gyrase and Human Topoisomerade II of DW224a, A New Quinolone antibacterial
- Transcription factor mimic compound produced through the study of structureactivity relationship (SAR)
- Immunomodulatory effect of an extract from the aerial part of Saururus chinensis
- Supercritical carbon dioxide extraction of Abies koreana W, essential oil
- Current Aspects of Boiequivalence Studies in Korea and the Standard Protocols of Bioequivalence Test based on the BE reports
- Anti-inflammatory activity of Ailnathus altissima
- Cytotoxic constituents from Evodia officinalis
- Pharmacognostical Study on the Studies on the Chinese Crude Drug " Man Sam "
- Anti-inflammatory and anti-asthmatic activity of Saururus chinensis
- Determination of gemfibrozil in human plasma using HPLC with fluorescence detection
- Therapeutic Potential of Histone Deacetylase Inhibitor 6-Lactam Base Hydroxamic Acid for Huntington's Disease
- Lycopus lucidus inhibits mast cell-depentent allergic reactions and inflammatory cytokines secretion
- Characterization of belotecan and topotecan absorption acrossCaco-2 cell monolayers
- The Development of Recursive Partitioning Model of Quinone Derivatives with Antifungal Activity
- Antitumor activity of two DNA vaccines to inhibit tumor metastasis and growth
- Physical properties and antimicrobial activities of leaf essential oil of Artemisia Lavandulaefolia DC
- Platycodin D lowers cholesterol in vivo and has anti-atherogenic properties in vitro
- Changes in Hepatic Drug Metabolizing Enzymes and Lipid peroxidation by Methanol Extract and Major Compound of Orostachys japonicus
- Anti-oxidant and Anti-inflammatory activity of Dioscorea quinqueloba component
- Improvement of the extraction efficiency of D-amygdalin when extract Armeniacae semen with Schizandrin Fructus powder.
- Immuno-pharmacological properties of panaxadiol and panaxatriol and their potential effects in neuroprotection in vitro
- Broad-spectrum antioxidant peptides derived from His residue-containing sequences present in human paraoxonasel,
- Characterization of Human Tissue Plasminogen Activator Produced in Urea Cycle Enzyme Expressing CHO Cell Line
- Metabolic Profiling Analyses of Polyamines in Human Urine as Ethoxy carbonylated Pentafluoropropionyl Derivatives by Gas Chromatography-Mass Spectrometry in Selected Ion Monitoring Mode
- Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells
- Induction of apoptosis in human leukemia U937 cells by 2-(4-bromophenyI)-3methy 1-1 H-indole (IND-8) involves activation of caspases and mitochodria-related proteins.
- A novel GGTase 1 inhibitor for development of new antifungal agent
- Anticancer constituents with a new and six known compounds isolated from the roots of Rubia cordifolia L.
- Evaluation of immunomodulating activities of various Echinacea samples
- Evidence of the Electronic Factor for the Highly Enantioselective Catalytic Efficiency of Cinchona-Derived Phase-Transfer Catalysts
- Novel benzoxathiol LYR-71 compound inhibits JAK-STAT pathway, leading to suppression of IFN-gamma-induced iNOS expression in macrophages
- Development of an intravenous itraconazole formulation using controlled release lipid nanoparticles
- Patent Map of Pharmaceutical composition for the treatment of Cardiovascular disease
- Characterization of Tributyl-Methyl Ammonium Transport across Rat Small Intestine : Role of Passive Absorption and Carrier-Mediated Secretion
- Pharmacokinetic Study of Glipizide in Healthy Male Subjects
- Neuroprotective action of petaslignolide A , an antioxidant from Petasites japonicus extract, against kainic acid neurotoxicity in mice brain
- Asymmetric synthesis of thioureido ceramides as anticancer agents
- The Standard Protocols of Bioequivalence Studies in Korea
- Ginsenoside Rh2 inhibits proliferation of human promyelocytic HL-60 leukemia cells via Go/Gi phase arrest and induction of di^erentiation
- Practical Synthesis of FTY720
- AKAP12 induces the blood-retinal barrier formation
- A New Lupane-Triterpene Glycoside from Leaves of Acanthopanax koreanum(III)
- Direct determination of estriol conjugates in amniotic fluid by colum-switching liquid chromatography with eiectrospray tandem mass spectrometry
- Analysis of silybin of compound cardus marianus extract soft capsules
- A new HPLC method to determine L-Cystine in pharmaceutical preparations
- Inhibition of Tamoxifen-induced Apoptosis by Phthalates in MCF-7 Human Breast Cancer Cells
- Selection of stereoisomers with biological activity by flexible docking
- Metabolic Profiling Analysis of Amino Acids in Human Hair by Gas Chromatography as Ethoxycarbonylated tert.-Butyldimethylsilyl Derivatives
- A New Butyrolactone Sesquilignan from the Seeds of Arctium lappa
- Phosphodiesterase inhibitors stimulate osteoclast formation by inducing TRANCE expression via PKA, ERK, and p38 MAPK pathways in osteoblasts
- Oral absorption of LMWH-DOCA in DMSO formulation in mice and monkeys
- A new stiibene from the roots of Polygonum multiflorum
- Rapid and Sensitive Determination of Perindopril in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry
- Size-controlled preparation of PLGA microspheres used for chemoembolization in cancer patients
- Bioequivalence of Klimain™ to Somalgen™(TaIniflumate 370mg)
- Relationship of Osteoporosis and oxidative stress; levels of urinary 8-isoPGFja decrease in Osteoporosis
- "The deguanilation of guanine-based nucleosides by the incubation of 2-bromopropane or other structurally related halogenated alkanes at the physiological condition"
- Biarylcarboxybenzamide derivatives as Potent Vanilloid Receptor Antagonistic Ligands
- Some compounds from the fruit of Hovenia acerba
- Activation of MAP Kinase Kinase (MKK)-6 Induces MMP-2 Upregulation Leading to Invasive Phenotype of Breast Epithelial Cells
- Syntheses and SAR of Substituted 1,1^-Diaminoketones as Candida albicans GGTase Type-I Inhibitors
- Ginsenoside R pl, a ginsenoside of major metaboiite, as a new Immunomodulatory regulator.
- Quantitative Aniaysis of Itraconazole in Human Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry.
- Determination of 3-chloro-l,2-propanediol in water by GC/MS
- Quaility monitering of Oriental Medicine
- Antinociceptive Antiinflammatory Effect of Monotropein Isolated from Morinda oifkinulis
- Resistance to Cethromycin Conferring Constitutive Resistance to Macrolides in Staphylococci
- The dextromethorphan analogue dimemorfan attenuates kainite-induced seizers via a l receptor activation: comparison with the effect of dextromethorphan
- Enantiomer Separation of Amino Acid Esters as Benzophenone Imine Derivatives Using Polysaccharide Derived Chiral Stationary Phases
- Vasorelaxant activity of the root extract of Rheum undulatum on the contractility of rat aorta
- Skin Permeation and Analgesic & Anti-inflammatory Effects of Ketorolac tromethamine Preparations Containing Menthol.
- Antimicrobial and Antioxidant Activities of Nepalese Medicinal Plants
- Anti-diabetic effect of Cariolus versicolor in mice
- Lactic acid bacteria as oral antigen protein carriers
- Evaluation of bioequivalence of propiverine tablet in healthy volunteers
- Structure and Biological Activity of Phenolic Compounds
- The cleavage of Cdc6, replication factor by caspase 3 promotes and induces apoptosis
- Optimization of informative spectral regions for the quantification of blood components using searching combination moving window partial least squares method with near infrared spectroscopy
- Achiral and Chiral Analysis of Multiple p-Blockers by Achiral Gas Chromatography
- Highly Sensitive Determination of Lacidipine in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry.
- Monoacyl lipoteichoic acid from pneumococci stimulates human cells but not mouse cells.
- ADME Prediction in Drug Discovery: Predictability Evaluation of Various ADME Prediction Softwares
- Antiproliferative Activity of a Novel S-lactam Base Histone Deacetylase Inhibitor via Selective Gene Expression
- Determination of isotretinoin in human plasma by high-performance liquid chromatography with ultraviolet detection
- Column-switching high-performance liquid chromatographic analysis of fluvastatin sodium in rat plasma by direct injection
- Isoflavonoid from Viola hondoensis, regulates the expression of matrix metalloproteinase-1 in young aged human skin flbroblasts
- Development of mobile phase with fluorescence in sugar analysis by HPLC
- Genetic polymorhisms of the MDRl genes and pharmacokinetics of losartan in healthy Korean subjects
- Molecular characterization of a lectin from Maackia fauriei
- Comparison of Two Different Extended Release Formulations of Venlafaxine in Healthy Male Volunteers
- Co-incorporation of antioxidants enhances the stability of all-trans retinol loaded in solid lipid nanoparticles
- Development of a capillary electrophoretic method for enantioseparation of tiropramide.
- Study of chitosan oligosaccharide on human kidney cell by MTT assay and LDH assay
- Topical gene delivery to the skin using cationic solid lipid nanoparticles
- Pharmacokinetic changes of enoxacin in uranyl nitrate-induced acute renal failure (U-ARF) rats
- Anti-Oxidative, Nitric Oxide and ProstaglandinEi Production Inhibitory Activities of Phenolic Compounds from the Seeds of Primus tomentosa Thunberg
- Metabolic inhibition of an antiestrogen by pharmaceutical excipients in human liver microsomes
- Apoptosis-accelerating activity of CYPIBI inhibitor 2,4,3'5'-tetraniethoxystilbene in HL-60 cells
- Point to consider on the efficacy and safety evaluation in dendritic cell immunotherapy
- Evaluation of the stability of TNF-related Apoptosis Inducing Ligand.
- Gas Chromatographic Profiling Analysis of Amines and Phenols for Clinical Applications
- A New Cytotoxic Compound of the Methylpyridine Class from a Marine-derived Streptomyces sp.
- Genetic polymorphisms and haplotypes of MDRl gene (exon 12, 21 and 26) in Korean population
- IdentiHcation of -1 Ribosomal Frameshifting Site of Borrelia burgdorferi B31 by Mutation Analysis.
- Metabolism of Ginsenoside Re by Human Intestinal Microflora and Their Estrogenic Effects
- The Pharmacokinetic Study of Fenoterol hydrobromide in Korean Healthy Volunteers by LC-ESI/MS/MS
- Inhibitory mechanism of novel benzoxathiol LYR-64 compound on IL-6 production in LPS-stimulated macrophages
- Supercritical carbon dioxide extraction of Abies koreana W. essential oil
- Subacute Oral Toxicity of Phenol derivative(MS) from Cordyceps militaris
- Enhancement of dissolution rate and bioavailability of amlodipine using spray-dried microspheres
- Highly Enantioselective Synthesis of (R)-a-Alkylserines via Phase-transfer Catalytic Alkylation of o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester using Cinchona derived catalysts
- Benzoxathiol LYR-64 compound down-regulates iNOS expression by preventing JAK2 activation in IFN-gamma-stimulated macrophages
- Effect of pharmaceutical excipients on chemical stability of proton pump inhibitor
- Formal synthesis of Lepadiformine.
- Transdermal delivery of low molecular weight heparin with ultraflexible liposomes
- Quantitative analysis of gabapentin in human plasma by gas chromatographymass spectrometry
- Cytotoxic activity of thioureido ceramide derivatives
- A dibenzyl-g-butyrolactone lignan from the stem-bark of Styrax japonica
- Isolation and Biological Activity of Sesquiterpene Lactone
- Study on Staminal Activities of the extracts of Watermellon and octacosanol
- Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide and cyclooxigenase-2 by chiisanoside via suppression of nuclear factor-KB activation in RAW 264.7 macrophage cells
- Modulation of macrophage functions by fractions containing proteinpolysaccharide complex from Lentinus edodes
- Purpureaside A, a glycoside isolated from Digitalis purpurea inhibits the induction of nitric oxide synthase through the blocking of AP-1 activation
- Anti-stress effects of the ginsenosides Rg3 and R bl on the changes in brain polyamine levels after immobilization stress
- Immunostimulating activity of Cariolus versicolor to activate macrophages in mice
- Determination of ranitidine in human plasma by high-turbulent liquid chromatography with ultraviolet detection
- Anti-Oxidative Effects of Quercetin-Glycosides Isolated from the Flower Buds of Tussilago farfara L.
- Effect of ochnaflavone, naturally occurring biflavonoid, on inflammatory response
- Dissociation in Characteristics of Tetraethylammonium Distribution to the Kidney Cortex and Kidney Medulla in Acute Renal Failure: Involvement engodenous effects to Organic Cation Transporter 2
- Pharmacokinetic interaction between verapamil and naringin in Rabbits
- Separation and Stability of Positional Isomers of PEGylated Somatostatin Analogue
- Educatonal effects of the drug abuse prevention program based ont the National Survey on the drug abuse in Korea
- Identification of Ym2 gene in mouse bone marrow-derived mast cells by IL-4 and expression of Ym2 protein by HEK 293 cells
- A lectin from coastal crab Macrophthalmus Japonicus
- Anti-Fatigue Effect of Lactic acid bacteria (Lactobacillus acidophilus,Bifidobacterium bifldum, Streptococcus thermophilus) in ICR Mice
- Sialic acid derivative-binding protein from Cordyceps militaris
- A pharmacological advantage of Ursodeoxycholic Acid in cytoprotection in primary rat microglia.
- A potent anti-complement activity of acylated sterol glucoside from Orostachys japonicus
- Antioxidative Effect of Epimedium koreanum in Ovariectomy.
- Broad-spectrum antioxidant peptides derived from His residue-containing sequences present in human paraoxonasel.
- Production of TNF-a and IL-2 by PBMC in vitro incubation with flavonoids
- Levels of urinary 3-hydroxy fatty acids increase in hyperthyroidism using gas chromatography-mass spectrometry
- Antioxidant activity of several subfractions from the extract of CBN-1 and KG
- Hypoxia-induced IL-6 production is associated with activation of MAP kinase,HIF-1, and NF-kB on HEI-OCl cells
- Anxiolytic-like effects of Phyllostachys nigra in mice
- Syntheses and Cytotoxicity Test of Quinobenzoxazine Analogues
- Intracellular Accumulation of ID-6105 in Ovarian Cancer Cell Line
- Preparation and Characterization of Lysozyme Nanoparticles using solution enhanced dispersion by supercritical fluid (SEDS) Process
- Antioxidant Activity of Smilacis Chinae Radix
- Regulatory Mechanisms and Their Therapeutic Implications of IL-12/IL-4 Production in T Helper Cell Differentiation
- Protective Effect of (S)-Bakuchiol from Psoralea corylifolia on Rat Liver Injury In Vitro and In Vivo
- Anti-Diabetic Effects of DY-101357, A Potent PPARs Agonist
- Anti-inflammatory Effects of Morinda citrifolia Extracts in Skin-incised Mice
- PHOTOSTABILITY STUDY OF AMLODIPINE PRODUCTS
- Inhibition of TGFpi-mediated PAI-1 induction by oltipraz through selective interruption of nuclear transport of Smad 3/Smad 4
- Anti-cancer effect of STB-HO (mineral complex containing rare earth elements) in nude mice transplanted human lung cancer cells
- Detection and identification of Mycobacteria by PCR-RFLP
- The Pharm acisfs Role in SigniHcant Hazardous Interactions of Duplicative Therapy Focusing Antipsychotics and Antibiotics for Drug Utilization Review
- The Anxiolytic-like Effects of Cinnamomum Cassia Related with 5 -H T ia and GABAa receptor in the Elevated Plus Maze
- Anti-diabetic Drug Development from Natural Resources
- Growth hormone booster attenuates memory impairment and oxidative stress in the genetic model of aging gene klotho mutant mice
- Hepatobiliary Transport of IH-901, a Potential Anticancer Agent, in Freshly Isolated and Sandwich-Cultured Rat Hepatocytes
- Rheological, mucoadhesive and release properties of thermosensitive gels for the treatment of hemorrhoids
- Apoptotic potential of ergolide, a sesquiterpene lactone from Inula britannica var chinensis
- Effect of 4-lBBL on the DC induced T cell activation : in vitro dose-dependency.
- IN2001 is a Novel Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vitro and in Vivo.
- Regulation of Tissue-Specific Gene Expression by Dynamic Change in Histone code
- Studies on the Constituents of Ostericum koreanum
- Determination of cinnamic acid and cinnamaldehyde in crude drugs by HPLCPDA
- Studies on development of a HPLC method to measure content recombinant interferon alpha-2
- No relationship between genetic polymorphisms in CYP2D6 and MDRl and cilostazol pharmacokinetics
- Pharmacokinetics of Amikacin in Korean Premature Infants
- DA-8159, A New Erectile Dysfunctional Drug
- Recent Technologies in Drug Delivery System
- Involvement of mutant presenilin 2 in the abnormality of lipid metabolism in developing Alzheimer^s disease
- In vitro peroxynitrite scavengers and two new biflavone glucosides from Ginkgo biloba leaves
- Solid-Phase synthetic method for racemic and Non-natural a-Amino Acids via Phase-Transfer Catalytic alkylation
- Inhibition of the induction of nitric oxide synthase by amentoflavone in macrophages
- Enhanced Oral Bioavailability of Genistein Formulated into Solid Lipid Microspheres
- Determination of carbamazepine by high-performance liquid chromatography in human plasma.
- Isolation of Saponins with the Inhibitory Effect on Nitric Oxide Formation from Pleurospermum kamtschaticum
- Effect of DW1350 on Acute Inflammation: Xylene-Induced Ear Acute Inflammation Mice Model
- Anti-Oxidative and Nitric Oxide Production Inhibitory Effect of Extract and Fractions from the Barks of Actinidia arguta
- A novel mechanosensitive channel identifled in sensory neurons
- Cardiopreotective effects of KR-32570, a novel N aM i수 exchanger inhibitor, in rats and dogs
- Determination of Ethambuto! in Human Plasma by a Validated HPLC Method and Its Application to Single-dose Pharmacokinetics
- KR-32560, a novel NHE-1 inhibitor exerts cardioprotective effects via reduction of oxidative stress in a rat model of ischemia/reperfusion-induced heart injury
- Effects of DA9102 on Dermatosis in magnesium-deficient hairless rats
- Effect of some herbal extracts'* mixture on postmenopausal urinary incontinence in ovariectomized rat.
- Effect of Ginsenoside Re and Its Metabolites Ginsenoside Rgl and Ginsenoside Rhl in Chronic Oxazolone-lnduced Mouse Dermatitis
- Enantioselective Synthetic Method for a-Alkylserine via Phase-Transfer Catalytic alkylation of 2-phenyl-2-oxazoline-4-carbonylcamphorsultani
- Deoxysulfamate Analogues of Methionyl and Isoleucyl Adenylates as Inhibitors of Methionyl-tRNA and Isoleucyl-tRNA Synthetases
- Identification of polyunsaturated fatty acid with anti-inflammation activity from the fruit of Actinidia polygama
- Determination of venlafaxine in human plasma by high-performance liquid chromatography with ultraviolet detection
- Oxidative cyclization of chalcones
- p-85 beta PIX differentially regulates cell motility via FAK and p38 MAP kinase phosphorylations
- 3D-QSAR study of 3 and 4-substituted cephems with HLE Inhibitory activity
- The effects of C. annuum L. leaf on cancer cell lines and the Mouse
- Regulation of Dendritic Spine Morphogenesis by PSD-95
- Introduction to The Concept and Practice Guideline of Drug Utilization Review
- The role of peroxiredoxin (Prx) I I in the kainic acid (KA)-induced neurotoxicity
- The finding of novel neutral Magnesium independent form Smase
- Current Evaluation of Biochips in KFDA
- Virtual Screening and Ligand Optimization for The Development of Novel Aminoacyl-tRNA Synthetase Inhibitors
- IdentiHcation and Functional Study of a Novel Form of 60kDa Mg dependent Neutral Sphingomyelinase
- Production of Recombinant hGM-CSF in Plant Cell Suspension Culture
- Acid induces COX-2 expression via ERK and p38 MAPK activation in cultured cat esophageal smooth muscle cells
- Psoralen derivatives block hKvl.5 Current
- Statistical Concepts in Bioequivalence Studies
- Positive improvements of climacteric symptoms by isoflavones extracted from Sophorae fructus, in ovariectomized Sprague-Dawley rats.
- The expectorant effect of Dioscorea quinqueloba component
- Cellular uptake and transfection efficiency of plasmid DNA using low molecular weight polyethylenimine
- Insulin Signaling in Regulation of Drug Metabolizing and Antioxidant Enzyme Expression
- Drug Interactions and Medication Teaching in Concurrent use of Herbal Medicines and Pharmaceutical Drugs
- Assurance of Food Safety: Food Xenochemicals
- Age-specific Contraindication of Therapeutics
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