병변내 시도포비어 주입술에 효과를 보인 재발성 눈물낭 기원 편평상피유두종 1예

• 영문명: A Case of Intralesional Cidofovir Injection for Recurrent Lacrimal Sac Squamous Papilloma
• 발행기관: 대한안과학회
• 저자명: 이연호 손준혁,Yeon Ho Lee, MD, Jun Hyuk Son, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number8, 1218~1223쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.08.15

영문 초록

Purpose: To report a case of treating a patient with intralesional cidofovir injection who had frequently recurring lacrimal sac squamous papilloma after several excision surgeries. Case summary: A 59-year-old man who had mass excision surgery at a different clinic nine months previously, visited our clinic to treat a recurring erythematous protruding mass near his left medial canthus that developed two months prior. Orbit CT showed a 15 x 25 mm-sized large mass located on the lacrimal sac adherent to medial orbital wall. An excision biopsy was performed and the histopathologic examination showed typical findings of squamous papilloma. Because the tumor recurred six months after the second surgery, we decided to perform adjuvant therapy using the antiviral agent cidofovir. The patient was treated with a 5 mg/mL intralesional cidofovir injection every three weeks. A transient recurrence presented on the upper lid at the third intralesional cidofovir injection site two months after the surgery, but the recurrent lesion improved after repeated injections. During the 12 months of follow-up, there were no complications and no evidence of recurrence. Conclusions: Intralesional cidofovir injections can be a safe and effective treatment for the management of recurrent squamous papilloma of the orbit, especially after total excision. J Korean Ophthalmol Soc 2014;55(8):1218-1223

키워드

Antiviral agent, Cidofovir, Intralesional injection, Squamous papilloma