눈물샘 상피종양의 임상적 분석

• 영문명: Clinical Analysis of Epithelial Tumors of the Lacrimal Gland
• 발행기관: 대한안과학회
• 저자명: 원재연 정수경 백지선 양석우,Jae Yon Won, MD, Su Kyung Jung, MD, Ji Sun Paik, MD, Suk Woo Yang, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number6, 795~800쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.06.15

영문 초록

Purpose: To analyze the clinical and radiologic findings and to evaluate the treatment and prognosis of epithelial tumor patients.
Methods: We retrospectively reviewed clinical and radiologic findings of 36 patients who had been histopathologically diagnosed with epithelial tumors of the lacrimal gland after biopsy and surgery at Seoul St. Mary's Hospital from May 2005 to October 2012.
Results: Among the patients with epithelial tumors of the lacrimal gland based on histopathological findings, there were 21 cases of pleomorphic adenoma, seven cases of dacryops, four cases of adenoid cystic carcinoma, two cases of adenocarcinoma, one case of benign oncocytoma, and one case of mucoepidermoid carcinoma. The characteristic clinical finding of epithelial tumors of the lacrimal gland was proptosis (52.7%). In contrast with benign epithelial tumors of the lacrimal gland, the characteristic clinical findings of malignant epithelial tumors of the lacrimal gland were limitation of motion (57.1%), diplopia (57.1%), ocular pain (42.9%), and decreased visual acuity (42.9%). The mean duration of the symptoms of malignant epithelial tumors (5.0 ± 4.2 months) was shorter than that of benign epithelial tumors (11.2 ± 11.1 months) (t-test, p = 0.034). In radiologic CT and MRI findings, there was minimal bony destruction in two cases of pleomorphic adenoma and calcification in one case of pleomorphic adenoma. Malignant epithelial tumors of the lacrimal gland, in contrast to benign tumors, showed characteristic bony destruction (57.1%), poorly marginated tumor outline (42.9%) and calcification (14.3%). The 57.1% of patients in this study with malignant tumors were treated with chemotherapy and radiotherapy after surgical treatment, and there was one case (14.3%) of recurrence after treatment.
Conclusions: Careful analysis of clinical and radiologic findings can lead to early diagnosis of malignant tumors.
J Korean Ophthalmol Soc 2014;55(6):795-800

키워드

Clinical findings, Epithelial tumors of the lacrimal gland, Radiologic findings