유리체절제술과 동시에 시행한 베바시주맙 주사 후 발생한 유리체 그물망

• 영문명: Vitreous Web after Pars Plana Vitrectomy and Bevacizumab Injection
• 발행기관: 대한안과학회
• 저자명: 김모세 채주병,Moses Kim, MD, Ju Byung Chae, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number5, 780~784쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.05.15

영문 초록

Purpose: To report a case of vitreous inflammation (vitreous web) after intravitreal bevacizumab injection accompanying pars plana vitrectomy (PPV) for the treatment of proliferative diabetic retinopathy with vitreous hemorrhage. Case summary: A 41-year-old female who underwent panretinal photocoagulation for diabetes mellitus (DM) retinopathy presented with decreased visual acuity in her right eye which was caused by vitreous hemorrhage. The patient underwent PPV with intravitreal bevacizumab injection. One day after surgery, the vitreous hemorrhage cleared and there was no inflammation in the anterior segment; however, multiple inflammatory white strands (vitreous web) were found in the vitreous cavity. She was diagnosed with non-infectious endophthalmitis and treated with topical steroid and additional oral steroids, resulting in clearance of the vitreous web on postoperative day 4. One month later, vitreous hemorrhage occurred in the other eye. PPV without bevacizumab injection cleared the vitreous hemorrhage with no evidence of vitreous web. Conclusions: Vitreous web-like inflammation can occur after intravitreal bevacizumab injection accompanying PPV for the treatment of DM vitreous hemorrhage. After eliminating infectious endophthalmitis based on lack of pain, conjunctival injection, anterior chamber hypopyon, and inflammatory cells, the web can be cleared without invasive intravitreal antibiotics injections. J Korean Ophthalmol Soc 2014;55(5):780-784

키워드

Intraocular inflammation, Vitreous hemorrhage