허혈성 3, 4, 6번 단독 뇌신경마비환자의 위험인자 및 예후

• 영문명: Risk Factors and Prognosis of Isolated Ischemic 3rd, 4th, 6th Cranial Nerve Palsy
• 발행기관: 대한안과학회
• 저자명: 천지웅 김대현,Ji Woong Chun, MD, Dae Hyun Kim, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number5, 740~745쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.05.15

영문 초록

Purpose: To investigate the clinical features and risk factors of ischemic third, fourth, sixth cranial nerve palsy. Methods: Retrospectively, we reviewed the medical records of 46 eyes of 46 patients who were diagnosed with ischemic third, fourth, sixth nerve palsy alone such as age of onset, risk factors, recovery rate and recovery time. Results: The mean age of onset was 64.9 years. Of the 46 patients, 15 patients (32.6%) in third cranial nerve palsy group, 15 patients (32.6%) in fourth cranial nerve palsy group, 16 patients (34.8%) in sixth cranial nerve palsy group. The risk factor of hypertension in 30 patients (65.2%) was the most common than other risk factors such as diabetes, hyperlipidemia, elevated blood hematocrit, ischemic heart disease, left ventricular hypertrophy, smoking. The mean number of risk factors was 2.3 ± 0.5 in third cranial nerve palsy group, 1.6 ± 1.1 in sixth cranial nerve palsy group, 1.4 ± 1.1 in fourth cranial nerve palsy group. Of the 46 patients, 42 patients (91.3%) were recovered. There was no significant difference in recovery rate by cranial nerve palsy. Recovery time of intracranial abnormalities group (10.5 ± 2.9 weeks) in brain imaging study was late as compared with that of no intracranial abnormalities group (7.5 ± 5.1 weeks). Conclusions: The overall recovery rate of isolated ischemic third, fourth, sixth cranial nerve was high. But if there are intracranial abnormalities in imaging study, it took a long time to recover. Also ischemic third cranial nerve palsy had multiple risk factors characteristically. J Korean Ophthalmol Soc 2014;55(5):740-745

키워드

Cranial nerve palsy, Ischemic, Recovery