공초점주사현미경에 의한 푹스각막이상증의 각막조직소견

• 영문명: Confocal Microscopic Findings of Corneal Tissue in Fuchs’ Corneal Endothelial Dystrophy
• 발행기관: 대한안과학회
• 저자명: 박영민 최범석 이종수,Young Min Park, MD, Beom Seok Choi, MD, Jong Soo Lee, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number9, 1435~1439쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.09.15

영문 초록

Purpose: To analyze the morphology and density of corneal tissue in patients with early stage Fuchs’ corneal endothelial dystrophy (FCED) by in vivo confocal microscopy (IVCM). Case summary: Each layer of the cornea in 2 patients with early-stage FCED was examined with IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., albignasego, Italy). Cross-sectioned corneal images of the corneal epithelium, Bowman’s layer, stromal layer, Descemet’s membrane, and endothelium were evaluated. Corneal epithelium, Bowman’s layer, and anterior stroma of both patients showed no abnormalities. Case 1 was diagnosed as Stage 1 FCED, demonstrating typical changes including pleomorphism, polymegathism, and the presence of guttae in the corneal endothelial layer. Case 2 was diagnosed as Stage 2 FCED, showing several hyper-reflective whitish dots in the posterior stroma, hypo-reflective vertical strands in the stroma adjacent to Descemet’s membrane, and pleomorphism, polymegathism, and guttae in the corneal endothelial layer. Conclusions: IVCM is a non-invasive and effective tool to diagnose early-stage FCED.

키워드

Confocal microscopy, Fuchs’ corneal endothelial dystrophy