후부판모양맥락망막염에서의 유리체강내 베바시주멥 선행 치료 후 임상경과

• 영문명: Clinical Course Following Intravitreal Bevacizumab Injection in Posterior Placoid Chorioretinitis
• 발행기관: 대한안과학회
• 저자명: 한세훈 임지원,Se Hoon Han, MD, Ji Won Lim, MD, PhD,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number5, 829~833쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.05.15

영문 초록

Purpose: To report the clinical course with optical coherence tomography findings following intravitreal bevacizumab injection in patients with posterior placoid chorioretinitis due to latent syphilis. Case summary: A 43-year-old woman presented with visual dimness in the right eye 3 days in duration. Fundus examination showed yellow, placoid lesions in the right eye and there was no cell reaction in the anterior chamber and vitreous. An intravitreal bevacizumab injection was given and systemic work-up performed. After 1 week, the macular lesion disappeared. However, photoreceptor disarrangement was present on spectral-domain optical coherence tomography image. On serologic test, the Venereal Disease Research Laboratory test, and fluorescent treponemal antigen absorption test were positive. She was referred to a division of infectious diseases and confirmed as latent syphilis. The patient received intramuscular penicillin 3 times weekly. Visual acuity and outer retinal abnormality further improved and there was no recurrence during the 6-month follow-up. Conclusions: Intravitreal bevacizumab injection added to antibiotic treatment may be considered for treating patients with posterior placoid chorioretinitis. Further studies are necessary to evaluate precise disease mechanisms and treatment.

키워드

Chorioretinitis, Posterior placoid chorioretinitis, Spectral-domain optical coherence tomography, Syphilis