만성신부전 환자에서 혈액투석 후의 안압 및 맥락막두께의 변화

• 영문명: Changes in Intraocular Pressure and Choroidal Thickness after Hemodialysis in Chronic Renal Failure Patients
• 발행기관: 대한안과학회
• 저자명: 전준우 이승우,Jun Woo Chun, MD, Seung Woo Lee, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number5, 752~756쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.05.15

영문 초록

Purpose: To evaluate the change of choroidal thickness and intraocular pressure (IOP) as a result of hemodialysis with chronic renal failure patients. In addition, the correlation between the change of choroidal thickness and IOP were evaluated. Methods: A total of 48 eyes of 48 chronic renal failure patients undergoing hemodialysis were included in the present study. IOP, blood pressure (systolic and diastolic), serum osmolality, central corneal thickness (CCT), and choroidal thickness were measured before and after hemodialysis. Choroidal thickness was measured using spectral domain ocular coherence tomography (SD-OCT). Results: After hemodialysis, IOP significantly decreased from 14.9 ± 2.3 mm Hg to 14.3 ± 2.1 mm Hg (p ＜ 0.001) and choroidal thickness significantly decreased from 352.2 ± 31.6 μm to 306.6 ± 29.0 μm (p ＜ 0.001). The other factors that significantly decreased after hemodialysis included serum osmolality (p ＜ 0.001) and blood pressure (p ＜ 0.001) except CCT (p = 0.285). There was a positive correlation between changes in IOP and choroidal thickness after hemodialysis (r = 0.319, p = 0.027). Conclusions: Decreased choroidal volume and thickness due to fluid loss may be involved in the mechanism of decreased IOP during hemodialysis. J Korean Ophthalmol Soc

키워드

Choroidal thickness, Hemodialysis, Intraocular pressure, Spectral domain ocular coherence tomography