한국인 특발성 시신경주위염의 임상양상

• 영문명: Clinical Manifestations of Idiopathic Optic Perineuritis in Korea
• 발행기관: 대한안과학회
• 저자명: 강혜민 김혜영,Hae Min Kang, MD, Hye Young Kim, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number7, 1016~1022쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.07.15

영문 초록

Purpose: To describe the clinical manifestations and magnetic resonance imaging (MRI) characteristics of idiopathic optic perineuritis patients in Korea. Methods: A retrospective chart review of 5 patients (6 eyes) with idiopathic optic perineuritis and 7 patients (7 eyes) with optic neuritis was performed. Results: The mean age of the 5 patients with idiopathic optic perineuritis was 59 years, and the mean age of the 7 patients with optic neuritis was 31.1 years. A relative afferent papillary defect (RAPD) was present in 4 eyes with idiopathic optic perineuritis, and in all 7 eyes with optic neuritis. All six eyes with idiopathic optic perineuritis showed relatively severe optic disc swelling, and 6 eyes with optic neuritis showed mild optic disc swelling. MRI demonstrated optic nerve sheath enhancement in all patients with idiopathic optic perineuritis and optic nerve enhancement in six patients with optic neuritis. Conclusions: On MRI, compared with optic neuritis, idiopathic optic perineuritis had a higher onset age, relatively severe optic disc swelling, and optic nerve sheath enhancement. Because idiopathic optic perineuritis is known to have different treatment strategies and prognosis compared with optic neuritis, differential diagnosis is crucial. The clinical manifestations and MRI characteristics of idiopathic optic perineuritis in the present study will help in the diagnosis of Korean patients. J Korean Ophthalmol Soc 2012;53(7):1016-1022

키워드

Idiopathic optic perineuritis, Optic neuritis