중심각막두께와 녹내장성 손상의 상관관계에 대한 연구

• 영문명: Correlation Between Central Corneal Thickness and Glaucomatous Damage
• 발행기관: 대한안과학회
• 저자명: 김윤전 나정화 이영록 성경림,Yoon Jeon Kim, MD, Jung Hwa Na, MD, Youngrok Lee, MD, Kyung Rim Sung, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number7, 1002~1010쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.07.15

영문 초록

Purpose: To evaluate the correlations between central corneal thickness (CCT) and optic disc and retinal nerve fiber layer (RNFL) parameters determined by spectral domain optical coherence tomography (SD OCT) and visual field (VF) global indices. Methods: The present study included 151 eyes diagnosed with open-angle glaucoma (OAG) and 135 glaucoma suspect (GS) eyes. The CCT, RNFL thickness, optic disc parameters, and VF global indices were measured. The relationships between CCT and RNFL thickness, optic disc parameters, and VF global indices were assessed by linear regression analysis. Results: Intraocular pressure (IOP, p < 0.001) and VF mean deviation (p = 0.005) in all participants, age (p = 0.017) and IOP (p = 0.003) in the GS group, and IOP (p = 0.002) and inferior RNFL thickness (p = 0.017) in the OAG group were significantly associated with CCT. Among the optic disc parameters, rim area, average cup/disc ratio, and vertical cup/disc ratio were significantly associated with CCT in all participants in the univariate but not multivariate analysis. Conclusions: Optic disc parameters obtained by SD OCT were not correlated with CCT in the OAG or GS group, while RNFL thickness and VF mean deviation showed associations. J Korean Ophthalmol Soc 2012;53(7):1002-1010

키워드

Central corneal thickness, Optic disc parameters, Retinal nerve fiber layer thickness, Spectral domain optical coherence tomography, Visual field indices