정상안압녹내장의 빠른 시야손상진행 위험요인

• 영문명: Risk Factors for Rapid Visual Field Progression in Normal-Tension Glaucoma
• 발행기관: 대한안과학회
• 저자명: 유인정 이정민 기창원,In Jeong Lyu, MD, Jung Min Lee, MD, Changwon Kee, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number7, 996~1001쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.07.15

영문 초록

Purpose: To evaluate risk factors of rapid visual field progression in normal-tension glaucoma. Methods: The authors of the present study reviewed the medical records of patients with normal-tension glaucoma who were treated between 2001 and 2011. The rapid progression group was composed of patients who showed a visual field index progression rate of ≤ -2.0%/yr, and the slow progression group was composed of patients who showed a visual field index progression rate of > -1.0%/yr using a Humphrey visual field analyzer (HFA). Age, sex, diabetes, hypertension, migraine history, family history of glaucoma, refractive error, central corneal thickness, disc hemorrhage, beta-zone parapapillary atrophy, baseline mean deviation, pattern standard deviation, initial IOP, mean follow-up IOP, peak IOP, IOP fluctuation, and number of eye drops between the 2 groups were compared. Results: Among the 52 patients with normal-tension glaucoma, 26 were classified into the rapid progression group and 26 were classified into the slow progression group. The mean visual field index progression rate was -3.92%/yr and -0.42%/yr, respectively. In the univariable model, migraine history, disc hemorrhage, beta-zone parapapillary atrophy, and number of eye drops were associated with rapid visual field progression. According to multivariate analysis, disc hemorrhage and number of eye drops were statistically significant risk factors. Conclusions: Disc hemorrhage and number of eye drops were associated with rapid visual field progression in normal tension glaucoma patients. J Korean Ophthalmol Soc 2012;53(7):996-1001

키워드

Normal-tension glaucoma, Progression, Visual field, Visual field index