비강 림프종과 동반된 안구내 자연살해/T세포 림프종 추정 1예

• 영문명: Presumed Intraocular Natural Killer/T-cell Lymphoma Combined with Nasal Lymphoma
• 발행기관: 대한안과학회
• 저자명: 정훈석 박상희 이재훈 이대영 남동흔,Hoon Seok Jeong, MD, Sang Hui Park, MD, Jae Hoon Lee, MD, PhD, Dae Yeong Lee, MD, Dong Heun Nam, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number7, 871~875쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.07.15

영문 초록

Purpose: To report a case of presumed intraocular natural killer/T-cell lymphoma (NKTL). Case summary: A 61-year-old male presented with visual disturbance of the left eye for duration of 3 years. He had been treated with systemic chemotherapy and radiotherapy for nasal NKTL 1 year prior. Inflammatory reaction in the anterior chamber and vitreous opacity were observed in the left eye. The patient was diagnosed with uveitis in the left eye at a local clinic 3 years prior to visiting us. Because the patient did not respond to anti-inflammatory therapy, we performed diagnostic and therapeutic vitrectomy. Intraoperatively, vitreous opacity was thin sheet like in appearance. The vitreous specimen contained few lymphoid cells and was positive for Epstein Barr virus-encoded RNA (EBER). Systemic workups showed no metastasis to other organs. The patient was treated with systemic methotrexate chemotherapy and intravitreal methotrexate injected 3 times (once per week). During the 12-month follow-up period after the last intravitreal injection, the recurrence of lymphoma and related uveitis was not observed. J Korean Ophthalmol Soc 2011;52(7):871-875

키워드

Diagnostic vitrectomy, Intraocular natural killer/T-cell lymphoma