갑상샘안병증에서 건성안에 영향을 미치는 인자

• 영문명: Risk Factors for Dry Eye in Thyroid-Associated Ophthalmopathy
• 발행기관: 대한안과학회
• 저자명: 김재련 임혜빈 정성근,Jae Ryun Kim, MD, Hye Bin Yim, MD, PhD, Sung Kun Chung, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number7, 771~776쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.07.15

영문 초록

Purpose: To investigate the risk factors for dry eye in thyroid-associated ophthalmopathy patients. Methods: The present retrospective study was conducted on 78 eyes in 39 patients diagnosed with thyroid-associated ophthalmopathy. The risk factors for dry eye in thyroid-associated ophthalmopathy patients were examined by analyzing data including tear break-up time, Schirmer’s test, age, gender, thyroid function status, palpebral fissure width, lagophthalmos, eyelid retraction, and exophthalmos through multiple logistic regression analysis. Results: The risk factors for dry eye disease were palpebral fissure width (OR = 3.422, p = 0.022) and lagophthalmos (OR = 13.068, p = 0.049). Age, gender, thyroid hormone status, eyelid retraction and exophthalmos did not show significant association with dry eye in multiple logistic regression analysis. The only risk factor for tear film break-up time less than 10 seconds was palpebral fissure width (OR = 2.787, p = 0.045), and none of the risk factors for Schirmer’s test less than 10 mm at 5 minutes were statistically significant. Conclusions: Risk factors for dry eye in thyroid ophthalmopathy patients were palpebral fissure width and lagophthalmos. J Korean Ophthalmol Soc 2011;52(7):771-776

키워드

Dry eye syndrome, Risk factors, Thyroid-associated ophthalmopathy