야간혈압하강이 녹내장의 진행에 미치는 영향

• 영문명: Correlation Between Nocturnal Dip and Progression of Glaucoma
• 발행기관: 대한안과학회
• 저자명: 서홍융 류원열 노세현,Hong Ryung Seo, MD, Won Yeol Ryu, MD, Sae Heun Rho, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number11, 1471~1478쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.11.15

영문 초록

Purpose: To investigate the effect of nocturnal dip influence on the progression of glaucomatous visual field defect. Methods: We performed 24hr ABPM and V/F tests on patients diagnosed with NTG (140 patients, 280 eyes) and POAG (84 patients, 168 eyes). Nocturnal dips below 10% were classified as non-dippers, and those above 10% were noted as dippers. The correlations among nocturnal dip, progression of glaucomatous visual field defect, and hypertension treatment were examined. Results: In NTG, dippers in both systolic and diastolic blood pressure furthered glaucomatous visual field defects, with a relative risk of approximately three times that of non-dippers. Hypertension treatment was not influenced by the progression of glaucomatous visual field defect but was influenced by dips in the systolic and diastolic pressures in NTG and in diastolic pressure in POAG. Nocturnal dips were more frequent in the group with progression of the visual field compared to those in the group with non-progression of the visual field in NTG. Conclusions: Dipper caused a progression of glaucomatous visual field defects in NTG and was influenced by hypertension treatment in NTG and POAG. Performing 24hr ABPM should be helpful for glaucoma patients with progression of a glaucomatous visual field defect even when the IOP is less than the target pressure. In addition, hypertension treatment should be considered an important factor in the treatment of glaucoma. J Korean Ophthalmol Soc 2010;51(11):1471-1478

키워드

Dipper, Hypertension treatment, Nocturnal dip, Progression of visual field defect, 24-hour blood pressure monitoring