프로프라놀롤 치료를 시행한 유아모세혈관종 1예

• 영문명: A Case of Periorbital Infantile Capillary Hemangioma Treated With Propranolol
• 발행기관: 대한안과학회
• 저자명: 이은경 정호경 김남주 이민정 권보상 곽상인,Eun Kyoung Lee, MD,, Ho-Kyung Choung, MD,, Nam Ju Kim, MD,, Min Joung Lee, MD,, Bo Sang Kwon, MD, Sang In Khwarg, MD,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number11, 1513~1519쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.11.15

영문 초록

Purpose: To report a case of periorbital infantile capillary hemangioma treated with propranolol. Case summary: A 6-month-old girl visited our clinic for a mass on the right upper eyelid, which had been present since birth. A dome-shaped, red-purple colored mass occupying almost the entire right upper eyelid was observed, and overlying branch-shaped telangiectases were also detected. The visual axis of the right eye was partially obscured, due to the ptotic eyelid, and her ability to fix and follow was poor in the right eye. The patient was diagnosed with infantile capillary hemagioma. Because amblyopia in her right eye was suspected, treatment with propranolol was initiated. After 2.5 months of propranolol treatment, the hemangioma decreased in size and volume dramatically, changed from red-purple to light red color, and softened. The ptosis of the right upper eyelid improved, as well as the ability of the right eye to fix and follow. No significant adverse effects (e.g. hypotension, bradycardia, hypoglycemia, bronchospasm, or elevated liver enzymes) were observed, except transient QTc prolongation during cotreatment with ibuprofen, due to an upper respiratory infection. Conclusions: Propranolol should be considered as a treatment option for periorbital infantile capillary hemangioma. Further clinical studies are required to establish the optimal guidelines and long-term outcome. J Korean Ophthalmol Soc 2010;51(11):1513-1519

키워드

Hemangioma of infancy, Infantile capillary hemangioma, Periorbital hemangioma, Propranolol