안와 내에 발생한 악성말초신경초종양 1예

• 영문명: A Case of Malignant Peripheral Nerve Sheath Tumor of the Orbit
• 발행기관: 대한안과학회
• 저자명: 이명옥 전찬 서연림 우경인 김윤덕,Myoung-Ok Lee, MD, Chan Jeon, MD Yeon-Lim Suh, MD, PhD Kyung-In Woo, MD, PhD, Yoon-Duck Kim, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number9, 1409~1413쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.09.15

영문 초록

Purpose: To present a case of malignant peripheral nerve sheath tumor (MPNST) in the orbit. Case summary: A 66-year-old man was evaluated for swelling of the left upper eyelid without pain that developed 2 months earlier. ACT scan and MRI of the orbit showed a large superior orbital mass with adjacent bony erosion, which had a central necrotic area. Incisional biopsy of the orbital mass was performed through a sub-brow incision. Histopathologic examination revealed a hypercellular tumor composed of spindle-shaped pleomorphic cells arranged in a fascicular pattern with necrotic foci. High-power magnification showed mitotic figures and nuclear pleomorphism. Subsequently, a malignant peripheral nerve sheath tumor was diagnosed. Conclusions: The possibility of malignant peripheral nerve sheath tumor should be considered in the differential diagnosis of an orbital mass which grows rapidly and shows bone invasion. Salvage surgery should be performed promptly to increase the likelihood of long-term survival.

키워드

Malignant peripheral nerve sheath tumor, Orbit