만성 중심장액맥락망막병증에서 절반 에너지를 적용한 광역학치료의 효과

• 영문명: Photodynamic Therapy With Verteporfin using Half Fluence for Chronic Central Serous Chorioretinopathy
• 발행기관: 대한안과학회
• 저자명: 장문희 김성우 오재령 허걸,Mun Hee Chang, MD, Seong Woo Kim, MD, PhD, Jae Ryung Oh, MD, PhD, Kuhl Huh, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number9, 1326~1333쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.09.15

영문 초록

Purpose: To evaluate the clinical results of half-fluence photodynamic therapy (PDT) using verteporfin in patients with chronic central serous chorioretinopathy (CSC). Methods: The author reviewed the charts of 20 patients (22 eyes) who underwent PDT for chronic central serous chorioretinopathy. All 22 eyes were treated using an irradiance of 300 mW over 83 second (25 J/cm2). Postoperative evaluation included improvements in visual acuity, complications, changes in central macular thickness with the optical coherence tomogram (OCT), and recurrence. Results: The best-corrected visual acuity improved significantly from 0.50±0.32 to 0.12±0.19 logMAR at 3 months (p<0.01), and the mean central macular thickness decreased from 377.7±86.3 μm to 166.2±29.3 μm at 3 months (p<0.01). Exudative serous macular detachments were resolved completely in all eyes within 3 months. There was no recurrence after PDT during the follow-up period. Conclusions: PDT using half fluence appeared to be a beneficial treatment option for patients with chronic CSC. Further studies are needed to verify treatment safety as well as the time and rate of recurrences.

키워드

Chronic central serous chorioretinopathy, Half fluence photodynamic therapy