당뇨망막병증에서 범망막광응고술 후 발생하는 시력 감소에 대한 트리암시놀론 후테논낭하주입술의 예방효과

• 영문명: The Effect of Posterior Subtenon Triamcinolone Injection in Panretinal Photocoagulation Induced Visual Dysfunction of Diabetic Retinopathy
• 발행기관: 대한안과학회
• 저자명: 황형빈 박영훈,Hyung-Bin Hwang, MD, Young-Hoon Park, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume50,number6, 864~869쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.06.15

영문 초록

Purpose: To evaluate the efficacy of a prophylactic posterior sub-Tenon’s capsule injection of Triamcinolone acetonide (TA) against macular edema and visual dysfunction by panretinal photocoagulation (PRP) in patients with severe nonproliferative and proliferative diabetic retinopathy. Methods: Thirty-eight eyes of 19 patients who have diabetic retinopathy without macular edema and whose retinopathy was bilateral and symmetrical were evaluated. Triamcinolone was injected into the posterior sub-Tenon’s capsule in one eye of the patients and nothing was injected in the other eye as a control. Two weeks later, PRP was performed every other week for 4 sessions on both eyes in all patients. The clinical course of visual acuity and macular edema was monitored for up to approximately 6 months after the initial PRP. Results: There was no statistically significant difference of visual acuity before PRP in the 2 groups (p＞0.05), and there was no macular edema in any patient. For a follow-up period of 6 months, visual dysfunction was more severe in the TA-injected eye than the control. However, the difference was not statistically significant (p＞0.05) throughout the follow-up period except at the 20-week time point. On the other hand, macular edema occurred in 2 eyes (10.5%) of the TA-injected group, and in 4 eyes (21.1%) of the control group. IOP elevation as a complication caused by TA-injection occurred in 2 eyes (10.5%). However, IOP was controlled successfully by anti-glaucomatic eye drops. Conclusions: Posterior sub-Tenon’s capsule injection of Triamcinolone is a safe and effective treatment modality for preventing PRP-induced visual dysfunction and macular edema.

키워드

Panretinal photocoagulation, Posterior sub-Tenon’s capsule injection of Triamcinolone acetonide