한국인에서 발생한 사르코이드 포도막염의 임상 양상

• 영문명: Clinical Features in Korean Patients with Sarcoid Uveitis
• 발행기관: 대한안과학회
• 저자명: 김태완 정흠 유형곤 ,Tae Wan Kim, M.D,,,, Hum Chung, M.D., Ph.D., Hyeong Gon Yu, M.D., Ph.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume49,number9, 1483~1490쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.09.15

영문 초록

Purpose: To investigate the clinical features of Korean patients with sarcoid uveitis. Methods: The medical records of patients with endogenous uveitis who were recruited from the uveitis clinic at Seoul National University Hospital were reviewed. Sex, age at presentation, ocular symptoms and signs, treatment, complications, and the rate of recurrence were analyzed. Results: Of 440 patients with endogenous uveitis, 31 (7.1%) with sarcoidosis were included. The mean age at onset was 54.5 years. Sarcoidosis patients with uveitis tended to be older than those without uveitis (44.1 years). Uveitis was the primary manifestation of sarcoidosis in 16 of 31 patients (51.6%). Anterior uveitis was the most common in terms of the anatomic location of inflammation (54.8%), and posterior involvement (38.7%) was not rare. Systemic corticosteroid therapy was administered to 28 patients (90.3%). Five patients (16.1%) received corticosteroids combined with immunosuppressive agents. Conclusions: Sarcoid uveitis is not a rare etiology of endogenous uveitis. Topical or systemic corticosteroids could control inflammation in most cases, but immunosuppressive agents are needed in a small percentage of patients. Steroids combined with immunosuppressive agents can prevent severe visual losses in such patients. J Korean Ophthalmol Soc 2008;49(9):1483-1490

키워드

Immunosuppressive agents, Korean, Sarcoid uveitis, Steroid