혈관줄무늬망막병증에서 발생한 맥락막신생혈관의 광역학치료 6예

• 영문명: Photodynamic Therapy for Choroidal Neovascularization in Angioid Streaks
• 발행기관: 대한안과학회
• 저자명: 정자영 조성원 이재흥,Ja Young Jung, M.D., Sung Won Cho, M.D., Ph.D., Jae Heung Lee, M.D., Ph.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number11, 1593~1598쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.11.30

영문 초록

Purpose: To evaluate the efficacy of photodynamic therapy (PDT) with verteporfin in the management of choroidal neovascularization (CNV) associated with angioid streaks. Case summary: Six eyes of four patients with CNV due to angioid streaks were treated with photodynamic therapy with verteporfin. Visual acuity testing, ophthalmologic examinations, photographs, and fluorescein angiograms were used to evaluate the results of PDT. Two of six eyes had subfoveal lesions, while four eyes had juxtafoveal lesions on initial examination. Conversion from a CNV to a fibrous scar lesion following PDT was observed in four eyes. Enlargement of the CNV was documented in two eyes at the final follow-up. Of a total of 6 eyes, the final best-corrected visual acuity decreased in 4 eyes and stabilized in 2 eyes. Conclusions: Photodynamic therapy can achieve short-term cessation or decrease of fluorescein leakage from chroidal neovascularization associated with angioid streaks. However, it does not alter the course of this disease, and multiple sessions are needed. Visual prognosis is poor.

키워드

Angioid streaks, Photodynamic therapy