눈물샘에 발생한 일차성 피지샘암 1예

• 영문명: A Case of Primary Sebaceous Carcinoma of the Lacrimal Gland
• 발행기관: 대한안과학회
• 저자명: 윤진숙 이상협 박종운 김세훈 최정범 이상렬,Jin Sook Yoon, M.D., Sang Hyup Lee, M.D., Jong Woon Park, M.D., Se Hoon Kim, M.D., Jung Bum Choi, M.D., Sang Yeul Lee, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number2, 312~318쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.02.28

영문 초록

Purpose: To report a case of very limited primary sebaceous carcinoma of the lacrimal gland that soon recurred and rapidly progressed after excision and radiotherapy. Methods: A 67-year-old man presented to our clinic with a history of proptosis in his right eye for 1 month. On physical examination, 4mm exophthalmos and a palpable mass at the superotemporal area of the lacrimal gland without tenderness were noted in his right eye. The eyelid was entirely normal on examination. A CT scan was taken which showed a heterogenous mass in the lacrimal gland area. We performed surgical excision and biopsy of the mass through lateral orbitotomy. Results: Primary sebaceous carcinoma of the lacrimal gland was diagnosed pathologically. A 63-Gy electron beam was irradiated for 6 weeks. Five months after the operation, a large mass was again palpable at the superotemporal orbital area. MRI revealed recurrence of the sebaceous carcinoma and its metastasis to the brain. Systemic metastasis in multiple organs was noted on PET scan. Conclusions: As primary sebaceous carcinoma of the lacrimal gland has a very poor prognosis, aggressive treatment such as exenteration should be considered, and a CT scan should be taken early on to find any recurrence or metastasis.

키워드

Lacrimal gland, Primary sebaceous carcinoma, Prognosis