코눈물관 부분폐쇄 치료시 마이토마이신 관류 여부에 따른 실리콘관 삽입술의 효과

• 영문명: Efficacy of Silicone Nasolacrimal Intubation with Mitomycin C Treatmentfor Treatment of Incomplete Nasolacrimal Duct Obstruction
• 발행기관: 대한안과학회
• 저자명: 김덕수 이용재,Deok Soo Kim, M.D., Yong Jae Lee, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number2, 181~185쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.02.28

영문 초록

Purpose: To investigate the efficacy and safety of adjunctive Mitomycin C (MMC) during silicone intubation (SI) for treatment of acquired incomplete nasolacrimal duct obstruction (NLDO). Methods: Nineteen eyes with incomplete NLDO underwent SI only (group I). 20 different eyes were administered adjunctive 0.4 mg/ml MMC for 4 minutes (group II). Diagnosis of incomplete NLDO was based upon subjective complaints of tearing, dye disappearance testing, clinical evidence of epiphora, and nasolacrimal duct irrigation. Follow-up examination was conducted at 1, 3, and 6 months. Results: Follow-up ranged from 3 to 15 months (mean, 6.1 months). Twelve (63.1%) eyes in group I and 14 (70.0%) eyes in group II had a successful outcome and remained symptom-free. Four (21.1%) eyes in group I and three (15.0%) eyes in group II showed improvement but still experienced periodic epiphora. The difference was not statistically significant (p=0.873). Conclusions: SI as a treatment for incomplete NLDO provides complete relief or substantial improvement in a significant percentage of patients but MMC application during SI did not benefit outcome.

키워드

Mitomycin C, Nasolacrimal duct obstruction, Silicone intubation