결절맥락막혈관병증에서 광역학치료 후 분지혈관망의 변화

• 영문명: Changes of Network Vessels after Photodynamic Therapy in Polypoidal Choroidal Vasculopathy
• 발행기관: 대한안과학회
• 저자명: 이필영 이원기,Phil Young Lee, M.D., Won Ki Lee, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number11, 1751~1758쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.11.30

영문 초록

Purpose: To evaluate whether the branching vascular network component of polypoidal choroidal vasculopathy (PCV) could be occluded after photodynamic therapy (PDT). Methods: A retrospective clinical study based upon indocyanine green angiogram was performed in 26 eyes of 26 patients having PCV and treated with PDT. Results: Of the 19 eyes which received a single session of PDT, none showed complete occlusion of the vascular network and 16 (84%) showed, at least in part, a persisting vascular network. Of the 7 eyes which had two session of PDT, 1 (14%) showed complete occlusion of the vascular network, and 3 (43%) showed, at least in part, a persisting vascular network. Changes in the vascular network could not be evaluated with exactness in 6 eyes. Of the 18 eyes achieving clinical improvement after single PDT, 3 had recurrence of hemorrhagic or exudative changes from new polypoidal lesions which originated from the persisting vascular network. Conclusions: It is difficult to expect complete occlusion of branching vascular network after PDT, which means future recurrence may not be prevented even though occlusion of polyps accompanied with clinical improvement can be achieved with PDT.

키워드

Branching vascular network, Polypoidal choroidal vasculopathy, Photodynamic therapy