수포각막병증환자에서 심층각막내피이식의 치료성적

• 영문명: Results of Deep Lamellar Endothelial Keratoplasty (DLEK)
• 발행기관: 대한안과학회
• 저자명: 정송이 이동훈 정태영 정의상,Song Ee Chung, M.D., Dong Hoon Lee, M.D., Tae Young Chung, M.D., Eui Sang Chung, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number11, 1743~1750쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.11.30

영문 초록

Purpose: To evaluate the clinical results of deep lamellar endothelial keratoplasty (DLEK) surgery in patients with bullous keratopathy. Methods: Seven eyes of 7 patients diagnosed with bullous keratopathy were evaluated for pre- and postoperative visual acuity, refractive error, astigmatism, and corneal topographic results. Specular microscopy and corneal pachymetry was performed in order to evaluate the corneal endothelial cell status. Postoperative complications such as graft rejection, infection, glaucoma, and graft dislocation were also evaluated. Results: Preoperative visual acuity improved from 0.006 (CF ~ 0.02) to 0.4 (0.1 ~ 0.5) at an average of 1.2±0.18 years of follow-up. Manifest refraction, topographic astigmatism, corneal endothelial cell density, and central corneal thickness at the final visit were 1.21±0.73D, 2.1±0.70D, 1304±682 cells/mm2, and 504±128 ?m respectively. Two eyes (28.6%) developed graft rejection, one of which recovered after intensive steroid treatment. However, one patient (14.3%) underwent penetrating keratoplasty due to graft failure at 6 months postoperatively. Seven of 7 eyes were noted to have graft dislocation, all of which were repositioned and attached after air injection or suture. Conclusions: DLEK surgery is an effective alternative to conventional penetrating keratoplasty for bullous keratopathy patients because of fast visual recovery and low incidence of postoperative astigmatism.

키워드

Deep lamellar endothelial keratoplasty (DLEK), Astigmatism, Visual acuity