후천성 3, 4, 6번 뇌신경마비의 임상 양상과 자연 경과

• 영문명: Clinical Features and Natural History of the Acquired Third, Fourth, and Sixth Cranial Nerve Palsy
• 발행기관: 대한안과학회
• 저자명: 박운철 김성준 유영석,Un-Chul Park, M.D.,, Seong-Joon Kim, M.D.,, Young-Suk Yu, M.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number9, 1555~1562쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.09.30

영문 초록

Purpose: To analyze the clinical features and natural history of acquired third, fourth, and sixth cranial nerve palsy. Methods: We reviewed the medical records of 89 patients who were diagnosed with acquired third, fourth, and sixth nerve palsy from January 2003 to March 2005. The natural course of the disease and the factors affecting recovery were analyzed for the 66 patients who had their first ocular examination within 3 months from onset and were followed up for at least 6 months. Results: The average age of onset was 50.1 years. The sixth cranial nerve was affected most frequently (n=43, 48.3%). Vascular disease (n=27, 30.3%) was most common etiology of cranial nerve palsy, followed by an undetermined cause (n=19, 21.3%). Of the 66 patients who had their first ocular examination within 3 months from onset and were followed up for at least 6 months, 40 (60.6%) patients showed a decrease in the angle of deviation by more than 10 prism diopters, and of these, 32 (48.5%) patients made a complete recovery from pareses. The recovery rates for patients with vascular disease or undetermined etiology (p=0.001), milder initial eyeball deviation and ocular motor restriction (p<0.001) were higher. Conclusions: In the natural course of the disease, the recovery rate of acquired third, fourth, and sixth nerve palsy was 60.6%. The most favorable prognosis occurred with vascular disease, undetermined etiology, and less severe paralysis on onset.

키워드

Cranial Nerve Palsy, Recovery, Vascular disease