망막신경섬유층 분석에 수정체혼탁이 미치는 영향?녹내장안과 정상안에서의 비교연구

• 영문명: Influence of Lens Opacity on Nerve Fiber Layer Analysis in Glaucomatous and Normal Eyes
• 발행기관: 대한안과학회
• 저자명: 김인태 박찬기 문정일 백남호,In-Tae Kim, M.D., Chan-Ki Park, M.D., Jung-Il Moon, M.D., Nam-Ho Baek, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number10, 1657~1662쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.10.31

영문 초록

Purpose: To analyze the retinal nerve fiber layer in glaucoma eyes and in normal eyes, before and after cataract surgery using GDx (Laser Diagnostic Technologies, Inc., San Diego, CA, U.S.A), - a scanning laser polarimetry, and to evaluate the effect of lens opacity on retinal nerve fiber layer analysis. Methods: Ocular examination and GDx analysis were performed one month before and after cataract surgery on 16 eyes of 10 patients affected with glaucoma and 14 normal eyes of 9 patients at St. Mary’s Hospital. Regarding the eyes affected with glaucoma, only those who showed no evidence of glaucoma progression on a visual field examination before and after the cataract surgery were included, and every cataract surgery was performed perfectly. Comparisons of the GDx parameters before and after cataract surgery were performed using the Wincoxon signed rank test. Results: All GDx parameters before and after cataract surgery in normal eyes showed no significant differences. In the glaucoma patients, differences in symmetry (p=0.047), superior ratio (p=0.007), ellipse modulation (p=0.001), and GDx number (p=0.008) were statistically significant. Conclusions: GDx is an examination based on the birefringent nature of retinal nerve fiber layer so the values can change according to changes in the cornea and lens, which are birefringent. This study compared the GDx parameters before and after cataract surgery of glaucoma patients and normal eyes. Our results showed that lens opacity has a minor and subtle effect on GDx parameters, and indicated the most sensitive parameters that reflect the change of retinal nerve fiber layer. Further studies should be performed using a larger sample with statistical support

키워드

Cataract, GDx, Glaucoma, Nerve fiber layer analysis