황반부종 치료를 위한 유리체강내 트리암시놀론 주입의 효용성

• 영문명: The Effectiveness of Intravitreal Triamcinolone Injection for the Treatment of Macular Edema
• 발행기관: 대한안과학회
• 저자명: 김덕수 박혜련 윤영희,Deok-Soo Kim, M.D., Hye-Ryun Park, M.D., Young-Hee Yoon, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number10, 1650~1656쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.10.31

영문 초록

Purpose: To investigate the effect of an intravitreal injection of triamcinolone acetonide (TA) for the treatment of macular edema due to several causes. Methods: One hundred eyes of 98 patients (DM, 58 eyes; branch retinal vein occlusion, 42 eyes) who received an intravitreal injection of 4mg (0.1cc) TA were included in this study. We performed preoperative and 1-, 3- and 6-month postoperative examinations that included stereoscopic biomicroscopy, fluorescein angiography (71 eyes) and optical coherence tomography (85 eyes). Pre- and postoperative visual acuity and IOP were measured. Results: After 1 month, visual improvement by 1 line or more was achieved in 62 eyes (62.0%). Sixty-five eyes (65.0%) and 49 eyes (57.6%) showed improved visual acuity after 3 and 6 months, respectively. Macular thickness decreased by 46.5% after 1 month, by 49.4% after 3 months, and by 50.8% after 6 months. There were no significant differences in visual improvement or thickness reduction between diabetic macular edema and edema secondary to branch retinal vein occlusion. There was no correlation between improvement of visual acuity and macular edema thickness decrease. Complications included a transient rise in intraocular pressure in 9 eyes and a secondary cataract in one eye. Conclusions: Intravitreal injection of triamcinolone acetonide 4 mg (0.1 cc) is an effective, simple and safe treatment for diabetic macular edema and macular edema secondary to branch retinal vein occlusion.

키워드

Intravitreal injection, Macular edema, Triamcinolone acetonide