Methampicillin Lysinate의 합성 및 항균작용

• 영문명: Synthesis and Antimicrobial Activty of Methampicillin Lysinate
• 발행기관: 대한약학회
• 저자명: 김종갑(Johng Kap Kim) 이숙경(Sook Kyung Lee)
• 간행물 정보: 『약학회지』제21권 제4호 (1977년), 211~213쪽, 전체 3쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1977.12.31

영문 초록

Since ampicillin, one of the important semi-synthetic derivatives of penicillins, is restricted in use because of its unfavorable physico-chemical and pharmacological properties, the author synthesized a new derivative, methampicillin lysinate and its physical and characteristics were determined. The antibacterial activity of this compound against ten species of Gram positive and negative bacteria in vitro showed that it was more active to Gram negative bacteria than the positive and that was three times more potent than ampicillin trihydrate.