옻나무 열수추출물에 의한 운동수행능력향상에 미치는 효과 및 기전 연구

• 영문명: Hotwater Extract of Rhus Verniciflua Stokes Improves Exercise Performance in Mice
• 발행기관: 대한약학회
• 저자명: 김민지 나천수 유영춘 홍철이
• 간행물 정보: 『약학회지』제58권 제3호 (2014년), 181~189쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.06.30

영문 초록

The aim of this was to evaluate the effects of Rhus Verniciflua Stoke (RVS) extract powder on the endurance capacity for the forced swimming mice. Thirty mice were divided into 3 groups including negative control, 250 (RVS-250) and 500 (RVS-500) mg/kg RVS extract powder groups for 4-times swimming exercises. The swimming times to exhaustion in RVS-250 and RVS-500 mice were prolonged 1.6- and 2.0-fold at 4 weeks compared with negative control mice, respec-tively. Blood biochemical parameters for AST, ALT, T-CHO and TG were not significantly different between RVS fed or neg-ative control mice. However, blood concentration of creatinine was significantly increased in RVS-250 mice, but not in RVS-500 mice. During the longer swimming exercise in RVS group, blood glucose and lactate levels were significantly decreased, but free fatty acid not changed. And also LDH levels were significantly decreased in RVS groups compared to negative con-trol mice. Hepatic lipid peroxidation was not affected by RVS, but SOD and catalase activity were significantly increased in RVS groups. Interestingly, the levels of testosterone and free testosterone were significantly increased in RVS groups before swimming exercise, but they were not significantly changed among groups after swimming exercise. The present results suggest that RVS extract powders may enhance swimming exercise performance by recovering the exercise-fatigue via reduction of blood LDH activity and by burning blood glucose as an energy source. These results imply that RVS-produced testosterone may act as an energy buster to enhance physical activity.

목차

재료 및 방법

실험결과

고찰 및 결론

감사의 글

References

키워드

Rhus Verniciflua Stokes,Swimming exercise,Testosterone,LDH,Lactate