학술논문
Adiponectin as a new paradigm for approaching Alzheimer's disease
이용수 12
- 영문명
- 발행기관
- 대한해부학회
- 저자명
- Juhyun Song Jong Eun Lee
- 간행물 정보
- 『Anatomy and Cell Biology』Vol.46(4), 229~234쪽, 전체 5쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2013.12.31
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국문 초록
영문 초록
Adiponectin is an adipocytokine released by the adipose tissue and has multiple roles in the immune system and in the metabolic syndromes such as cardiovascular disease, Type 2 diabetes, obesity and also in the neurodegenerative disorders including Alzheimer's disease. Adiponectin regulates the sensitivity of insulin, fatty acid catabolism, glucose homeostasis and anti-inflammatory system through various mechanisms. Previous studies demonstrated that adiponectin modulates memory and cognitive impairment and contributes to the deregulated glucose metabolism and mitochondrial dysfunction observed in Alzheimer's disease. Here, we aim to summarize recent studies that suggest the potential correlation between adiponectin and Alzheimer's disease.
목차
Abstract
Introduction
The Effect of Adiponectin on Brain Insulin System
The Role of Adiponectin on Neuroinflammation
The Potential of Adiponectin to Target Alzheimer's Disease
Future Perspective
References
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- Adiponectin as a new paradigm for approaching Alzheimer's disease
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