산전 검진의 최신 지견

• 영문명: The recent trend of prenatal screening
• 발행기관: 대한의학유전학회
• 저자명: 황도영(Doyeong Hwang)
• 간행물 정보: 『대한의학유전학회지』제5권 제1호, 7~14쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.06.30

영문 초록

Twenty years have passed since a prenatal screening for Down syndrome and neural tube defect was applied to obstetric field. The Quad test (AFP, hCG, uE3, Inhibin-A) of the second trimester and the combination test (PAPP-A, hCG, NT) of the first trimester became popular now. The recent trend of prenatal screening is to combine these two screening tests together in order to increase a detection rate of Down syndrome. Three types of screening methods are introduced as follows; integrated test, sequential test and contingent test. In addition to combination of each test, an incorporation of characteristic ultrasound findings of Down syndrome is suggested for its risk calculation. The absence of fetal nasal bone would be a very useful marker especially in the first trimester screening test. According to a change of way calculating risk of Down syndrome, obstetrician's role will be more increased not by passive participation, but by active participation using ultrasound in risk calculation.

목차

Introduction

Prenatal Screening by First or Second Trimester Markers

Prenatal Screening Combining First and Second Trimester Markers

Comparison of Combining Prenatal Screening Tests

USG Findings as Soft Marker in Second Trimester

Prospects and Problems

참고문헌

키워드

Prenatal screening