알츠하이머병의 심각도에 따른 신경정신행동 증상의 차이

• 영문명: Behavioral and Psychological Symptoms according to Severity in Patients with Alzheimer's Disease
• 발행기관: 대한노인정신의학회
• 저자명: 장기원(Ki Won Jang) 김지혜(Ji-Hae Kim) 안인숙(Inn-Sook Ahn) 김도관(Doh Kwan Kim)
• 간행물 정보: 『노인정신의학』노인정신의학 제13권 제2호, 77~82쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2009.12.30

영문 초록

Objectives : Our study investigated the behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD) patients with three groups (mild, moderate, severe) and prevalence of BPSD with the severity of AD. Method : In a study group of 338 patients with AD (mild : 184, moderate : 99, severe : 55), information on gender, age, education was collected. The severity of dementia was measured by the Korean version of mini-mental status examination (K-MMSE) and Clinical dementia rating (CDR). The Korean version of Neruopsychiatric Inventory (K-NPI) was administered to all patients. Results : Depression/dysphoria, apathy/indifference, irritability/lability, anxiety were frequent in the mild AD group. Apathy/indifference, Depression/dysphoria, agitation/aggression, delusion were frequent in the moderate AD group. Apathy/indifference, agitation/aggression, aberrant motor behavior, nighttime behavior, anxiety were frequent in the severe AD group. Conclusion : These observations suggest that delusion was a more dominant symptom in moderate AD group and the prevalence of depression declined in severe AD group.

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신경정신행동 검사 알츠하이머병 Neuropsychiatric inventory Alzheimer's disease CDR