혈관성 치매의 병인 및 발병기전

• 영문명: Vascular Dementia, Pathophysiology and Classification
• 발행기관: 대한노인정신의학회
• 저자명: 김범생(Beum Saeng Kim)
• 간행물 정보: 『노인정신의학』노인정신의학 제3권 제2호, 95~100쪽, 전체 6쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1999.12.30

영문 초록

Vascular dementia (VaD) is a dementia syndrome resulting from brain dysfunction produced by cerebrovascular disease. It is one of the most common causes of in the elderly, along with Alzhedimer's disease. Identification of VaD is particularly importent since its course may be modifiable through controlling risk factors. Hypxic-ischemic injury is responsible for most of VaD, and leukoencephalopathy and lacunes；some have traditional cortical infarctions. Clinical course of VaD is variale and not all the cases exhibit a classic stepwise progression. The clinical manifestations of VaD is include focal neurologic signs, extrapyramidal dysfunction, and incontinence. Neurobehaviaral abnormalities most often resemble those of subcortical dementia, but some patients manifest cortical dysfunction syndromes (aphasia, agnosia, apraxia). Personality changes and depression are common. A variety of pathological alterations associated with VaD include arterial territory infarctions, laminar necrosis, granular atrophy, sclerosis, lacunes, and subcortical leukoencephalopathy. Diagnosis of VaD depends on meeting following three criteria；1) dementia, 2) clinical and neuroimaging evidence of cerbrovascular disease, and 3) a compelling temporal relationship between the cognitive changes and the vascular insults. Treatment of VaD includes prevention of further vascular injury, control of neuropsychiatric disturbances, and application of appropriate rehabilitative strategies.

목차

혈관성치매의 원인적 유형 분류

혈관성치매의 임상적 접근

혈관성 치매와 알쯔하이머형 치매

키워드

VaD vascular dementia MID multi infarc demetia