항우울제 중단 증후군

• 영문명: Antidepressant Discontinuation Syndrome
• 발행기관: 대한신경정신의학회
• 저자명: 김세현 김용식 강웅구
• 간행물 정보: 『신경정신의학』제63권 제2호, 104~115쪽, 전체 12쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2024.05.31

국문 초록

Since selective serotonin reuptake inhibitors were introduced in clinical practice in the 1990s, an-tidepressant prescriptions have steadily increased. In addition to the prescriptions by psychia-trists, antidepressant prescriptions by non-specialists have also increased. An advanced under-standing of the pharmacological and clinical characteristics of antidepressants is essential to improving the treatment response of depressive disorders and the quality of life of patients. Anti-depressant withdrawal or discontinuation syndrome can frequently occur if antidepressant main-tenance is discontinued without a pre-planned clinical strategy. Nevertheless, it is often unrecog-nized or mistaken for other clinical situations. This causes patient distress and ultimately reduces long-term treatment compliance. Inappropriate therapeutic decisions can be made if clinicians do not recognize antidepressant discontinuation syndrome. Antidepressant withdrawal is com-mon and preventable. This issue must be recognized because it can be adjusted through appro-priate clinical management. This article systematically reviews the clinical features, biological mechanisms, coping strategies, and antidepressant discontinuation strategies related to antide-pressant discontinuation syndrome.

목차

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금단의 특성 및 경과

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키워드

Antidepressant Withdrawal Selective serotonin reuptake inhibitor Serotonin norepinephrine reuptake inhibitor