감 추출물이 아토피 피부염 관련 사이토카인 분비에 미치는 효과

• 영문명: Effect of Diospyros kaki extracts on atopic dermatitis-related cytokines
• 발행기관: 한국축산식품학회
• 저자명: 홍창의 유수연
• 간행물 정보: 『Food and Life』제2023권 제3호, 77~84쪽, 전체 8쪽
• 주제분류: 농수해양 > 식품과학
• 파일형태: PDF
• 발행일자: 2023.11.30

국문 초록

Diospyros kaki, also known as persimmon, has been used in traditional medicine for its potential health benefits. In this study, we employed 1,3-butylene glycol extract (DBG) and ethanol extract (DET) to investigate their anti-atopic dermati-tis (AD) activity. The results showed that DBG and DET were effective in reducing AD-related cytokines such as IL-8, TNF-α, and immunoglobulin E. Additionally, DBG and DET both upregulated the Th1 cytokine, IL-2. Furthermore, both extracts exhibited significant superoxide dismutase-like activities. These findings collectively suggest that D. kaki ex-tracts may be beneficial in improving AD due to their immunomodulatory and antioxidant properties.

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키워드

atopic dermatitis Diospyros kaki cytokine