Radiomics; A Potential Next “Omics” in Psychiatric Disorders; An Introduction

• 영문명: Radiomics; A Potential Next “Omics” in Psychiatric Disorders; An Introduction
• 발행기관: 대한신경정신의학회
• 저자명: Mohammadreza Alizadeh Manoj Tanwar Amir H Sarrami Ramin Shahidi Aparna Singhal Houman Sotoudeh
• 간행물 정보: 『Psychiatry Investigation』제20권 제7호, 583~592쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2023.07.31

영문 초록

Psychiatric disorders remain one of the most debilitating conditions; however, most patients are never diagnosed and do not seek treatment. Despite its massive burden on modern society and the health system, many hurdles prevent proper diagnosis and management of these disorders. The diagnosis is primarily based on clinical symptoms, and efforts to find appropriate biomarkers have not been practical. Through the past years, researchers have put a tremendous effort into finding biomarkers in “omics” fields: genomics, transcriptomics, proteomics, metabolomics, and epigenomics. This article reviews the evolving field of radiomics and its role in diagnosing psychiatric disorders as the sixth potential “omics.” The first section of this paper elaborates on the definition of radiomics and its potential to provide a detailed structural study of the brain. Following that, we have provided the latest promising results of this novel approach in a broad range of psychiatric disorders. Radiomics fits well within the concept of psychoradiology. Besides volumetric analysis, radiomics takes advantage of many other features. This technique may open a new field in psychiatry for diagnosing and classifying psychiatric disorders and treatment response prediction in the era of precision and personalized medicine. The initial results are encouraging, but radiomics in psychiatry is still in its infancy. Despite the extensive burden of psychiatric disorders, there are very few published studies in this field, with small patient populations. The lack of prospective multi-centric studies and heterogeneity of studies in design are the significant barriers against the clinical adaptation of radiomics in psychoradiology.

목차

INTRODUCTION

INTRODUCTION TO RADIOMICS

CURRENT RADIOMICS APPLICATIONS IN PSYCHIATRY

DISCUSSION

CONCLUSION

REFERENCES

키워드

Mental disorders Depressive disorder Schizophrenia Bipolar disorder Attention deficit disorder with hyperactivity Neuroimaging