학술논문
Roles of non-coding RNAs in intercellular crosstalk in cardiovascular diseases
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- 영문명
- Roles of non-coding RNAs in intercellular crosstalk in cardiovascular diseases
- 발행기관
- 대한생리학회-대한약리학회
- 저자명
- 임영환 김영국
- 간행물 정보
- 『The Korean Journal of Physiology & Pharmacology』제27권 제4호, 289~298쪽, 전체 10쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2023.07.31
4,000원
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국문 초록
영문 초록
Complex diseases including cardiovascular disease are caused by a combination of the alternation of many genes and the influence of environments.
Recently, non-coding RNAs (ncRNAs) have been shown to be involved in diverse diseases, and the functions of various ncRNAs have been reported. Many researchers have elucidated the mechanisms of action of these ncRNAs at the cellular level prior to in vivo and clinical studies of the diseases. Due to the characteristics of complex diseases involving intercellular crosstalk, it is important to study communication between multiple cells. However, there is a lack of literature summarizing and discussing studies of ncRNAs involved in intercellular crosstalk in cardiovascular diseases.
Therefore, this review summarizes recent discoveries in the functional mechanisms of intercellular crosstalk involving ncRNAs, including microRNAs, long non-coding RNAs, and circular RNAs. In addition, the pathophysiological role of ncRNAs in this communication is extensively discussed in various cardiovascular diseases.
목차
INTRODUCTION
REGULATION OF INTERCELLULAR CROSSTALK OF ncRNAs
CONCLUSION
FUNDING
ACKNOWLEDGEMENTS
CONFLICTS OF INTEREST
REFERENCES
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